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Michael Stokes
Michael Stokes
Postdoctoral Fellow, University of Toronto
Adresse e-mail validée de utoronto.ca
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Transferrin receptor is a specific ferroptosis marker
H Feng, K Schorpp, J Jin, CE Yozwiak, BG Hoffstrom, AM Decker, ...
Cell reports 30 (10), 3411-3423. e7, 2020
4862020
Multivalent small-molecule pan-RAS inhibitors
ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ...
Cell 168 (5), 878-889. e29, 2017
2572017
MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling
D Venkatesh, NA O'Brien, F Zandkarimi, DR Tong, ME Stokes, DE Dunn, ...
Genes & development 34 (7-8), 526-543, 2020
1792020
Detection of parasitic plant suicide germination compounds using a high-throughput Arabidopsis HTL/KAI2 strigolactone perception system
S Toh, D Holbrook-Smith, ME Stokes, Y Tsuchiya, P McCourt
Chemistry & biology 21 (8), 988-998, 2014
1322014
Interplay between sucrose and folate modulates auxin signaling in Arabidopsis
ME Stokes, A Chattopadhyay, O Wilkins, E Nambara, MM Campbell
Plant Physiology 162 (3), 1552-1565, 2013
962013
Copper-binding small molecule induces oxidative stress and cell-cycle arrest in glioblastoma-patient-derived cells
K Shimada, E Reznik, ME Stokes, L Krishnamoorthy, PH Bos, Y Song, ...
Cell chemical biology 25 (5), 585-594. e7, 2018
732018
Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19
H Liu, S Iketani, A Zask, N Khanizeman, E Bednarova, F Forouhar, ...
Nature communications 13 (1), 1891, 2022
522022
Towards personalized agriculture: what chemical genomics can bring to plant biotechnology
ME Stokes, P McCourt
Frontiers in Plant Science 5, 96010, 2014
172014
PERK inhibition by HC-5404 sensitizes renal cell carcinoma tumor models to antiangiogenic tyrosine kinase inhibitors
ME Stokes, V Calvo, S Fujisawa, C Dudgeon, S Huang, N Ballal, L Shen, ...
Clinical Cancer Research 29 (23), 4870-4882, 2023
42023
Optimization of a novel mandelamide-derived pyrrolopyrimidine series of PERK inhibitors
ME Stokes, MD Surman, V Calvo, D Surguladze, AH Li, J Gasparek, ...
Pharmaceutics 14 (10), 2233, 2022
42022
A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response–Dependent Survival of Quiescent Cancer Cells
V Calvo, W Zheng, A Adam-Artigues, KA Staschke, X Huang, JF Cheung, ...
Clinical Cancer Research 29 (24), 5155-5172, 2023
32023
Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation
ME Stokes, JC Small, A Vasciaveo, K Shimada, T Hirschhorn, A Califano, ...
Scientific Reports 10 (1), 10748, 2020
32020
Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers
ME Stokes, A Vasciaveo, JC Small, A Zask, E Reznik, N Smith, Q Wang, ...
Cell Chemical Biology, 2023
22023
Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
AP Sobinoff, S Di Maro, RRJ Low, R Benedetti, S Tomassi, A D'Aniello, ...
Cell Chemical Biology 30 (12), 1652-1665. e6, 2023
12023
Erratum: Detection of parasitic plant suicide germination compounds using a high-throughput Arabidopsis HTL/KAI2 strigolactone perception system (Chemistry & Biology (2014) 21 …
S Toh, D Holbrook-Smith, ME Stokes, Y Tsuchiya, P McCourt
Chemistry and Biology 21 (9), 1253, 2014
12014
HC-7366, a potent GCN2 activator, complements belzutifan, a HIF-2⍺ antagonist, by providing combination benefit in belzutifan-sensitive models and monotherapy activity in …
ME Stokes, F Tameire, P Wojnarowicz, S Fujisawa, C Dudgeon, S Huang, ...
Cancer Research 84 (6_Supplement), 4615-4615, 2024
2024
Blood Product Support in Multiple Myeloma Patients Undergoing Autologous Bone Marrow Transplantation May Predict Improved Outcome.
IL Pavkov, M Shoukier, MAH Mian, M Stokes, Y Reategui, P Nain, ...
Transplantation and Cellular Therapy 30 (2), S393, 2024
2024
Improving Clinical Outcomes in APL: Weight Maintenance Strategies to Reduce Complications during Induction Therapy
S Desai, A Shah, M Stokes, D Bradshaw, M Mian, A Chauhan, ...
Blood 142, 5873, 2023
2023
Hidac Consolidation Cycles May Impede Stem Cell Transplant Planning for High-Risk Acute Myeloid Leukemia Patients
M Stokes, D Bradshaw, Y Reategui, I Pavkov, M Mian, LJ Bryan, ...
Blood 142, 5854, 2023
2023
Financial Trends of AML Patients over the Past Decade
M Dalgetty, M Shoukier, D Bradshaw, F Boghani, S Athota, A Shah, ...
Blood 142, 5876, 2023
2023
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