Edda G Schulz
Edda G Schulz
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Spatial partitioning of the regulatory landscape of the X-inactivation centre
EP Nora, BR Lajoie, EG Schulz, L Giorgetti, I Okamoto, N Servant, T Piolot, ...
Nature 485 (7398), 381-385, 2012
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-γ and interleukin-12
EG Schulz, L Mariani, A Radbruch, T Höfer
Immunity 30 (5), 673-683, 2009
Jarid2 is implicated in the initial Xist-induced targeting of PRC2 to the inactive X chromosome
ST da Rocha, V Boeva, M Escamilla-Del-Arenal, K Ancelin, C Granier, ...
Molecular cell 53 (2), 301-316, 2014
Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes
Y Zhan, L Mariani, I Barozzi, EG Schulz, N Blüthgen, M Stadler, G Tiana, ...
Genome research 27 (3), 479-490, 2017
The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network
EG Schulz, J Meisig, T Nakamura, I Okamoto, A Sieber, C Picard, ...
Cell stem cell 14 (2), 203-216, 2014
Short‐term memory in gene induction reveals the regulatory principle behind stochastic IL‐4 expression
L Mariani, EG Schulz, MH Lexberg, C Helmstetter, A Radbruch, ...
Molecular systems biology 6 (1), 359, 2010
Role and control of X chromosome dosage in mammalian development
EG Schulz, E Heard
Current opinion in genetics & development 23 (2), 109-115, 2013
Direct comparison of a stable isolated Hsp70 substrate-binding domain in the empty and substrate-bound states
JF Swain, EG Schulz, LM Gierasch
Journal of Biological Chemistry 281 (3), 1605-1611, 2006
Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features
LBA e Sousa, I Jonkers, L Syx, I Dunkel, J Chaumeil, C Picard, B Foret, ...
Genome research 29 (7), 1087-1099, 2019
A symmetric toggle switch explains the onset of random X inactivation in different mammals
V Mutzel, I Okamoto, I Dunkel, M Saitou, L Giorgetti, E Heard, EG Schulz
Nature structural & molecular biology 26 (5), 350-360, 2019
Identification of X-chromosomal genes that drive sex differences in embryonic stem cells through a hierarchical CRISPR screening approach
O Genolet, AA Monaco, I Dunkel, M Boettcher, EG Schulz
Genome Biology 22, 1-41, 2021
Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus
RAF Gjaltema, T Schwämmle, P Kautz, M Robson, R Schöpflin, LR Lustig, ...
Molecular Cell 82 (1), 190-208. e17, 2022
Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution
G Pacini, I Dunkel, N Mages, V Mutzel, B Timmermann, A Marsico, ...
Nature Communications 12 (1), 3638, 2021
Dosage sensing, threshold responses, and epigenetic memory: a systems biology perspective on random X‐chromosome inactivation
V Mutzel, EG Schulz
Bioessays 42 (4), 1900163, 2020
CRISPR/dCas9 switch systems for temporal transcriptional control
RAF Gjaltema, EG Schulz
Epigenome Editing: Methods and Protocols, 167-185, 2018
X-chromosome dosage as a modulator of pluripotency, signalling and differentiation?
EG Schulz
Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017
CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression
G Noviello, RAF Gjaltema, EG Schulz
Nature Communications 14 (1), 3225, 2023
Dissecting molecular phenotypes through FACS-based pooled CRISPR screens
O Genolet, L Ravid Lustig, EG Schulz
Embryonic Stem Cell Protocols, 1-24, 2022
Regulatory principles and mechanisms governing the onset of random X-chromosome inactivation
T Schwämmle, EG Schulz
Current Opinion in Genetics & Development 81, 102063, 2023
Epigenetic dynamics during capacitation of naïve human pluripotent stem cells
J Agostinho de Sousa, CW Wong, I Dunkel, T Owens, P Voigt, A Hodgson, ...
Science Advances 9 (39), eadg1936, 2023
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