| The distinct genetic pattern of ALS in Turkey and novel mutations A Özoğuz, Ö Uyan, G Birdal, C Iskender, E Kartal, S Lahut, Ö Ömür, ... Neurobiology of aging 36 (4), 1764. e9-1764. e18, 2015 | 105 | 2015 |
| Ataxin-2 (Atxn2)-knock-out mice show branched chain amino acids and fatty acids pathway alterations D Meierhofer, M Halbach, NE Şen, S Gispert, G Auburger Molecular & cellular proteomics 15 (5), 1728-1739, 2016 | 89 | 2016 |
| Efficient prevention of neurodegenerative diseases by depletion of starvation response factor Ataxin-2 G Auburger, NE Sen, D Meierhofer, AN Başak, AD Gitler Trends in neurosciences 40 (8), 507-516, 2017 | 64 | 2017 |
| Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels NE Sen, J Drost, S Gispert, S Torres-Odio, E Damrath, M Klinkenberg, ... Neurobiology of disease 96, 115-126, 2016 | 37 | 2016 |
| Elevated global DNA methylation is not exclusive to amyotrophic lateral sclerosis and is also observed in spinocerebellar ataxia types 1 and 2 H Hamzeiy, D Savaş, C Tunca, NE Şen, A Gündoğdu Eken, I Şahbaz, ... Neurodegenerative Diseases 18 (1), 38-48, 2018 | 36 | 2018 |
| Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation NE Sen, J Canet-Pons, MV Halbach, A Arsovic, U Pilatus, WH Chae, ... Neurobiology of disease 132, 104559, 2019 | 34 | 2019 |
| Quantitative global proteomics of yeast PBP1 deletion mutants and their stress responses identifies glucose metabolism, mitochondrial, and stress granule changes G Seidel, D Meierhofer, NE Şen, A Guenther, S Krobitsch, G Auburger Journal of proteome research 16 (2), 504-515, 2017 | 31 | 2017 |
| Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression J Canet-Pons, NE Sen, A Arsović, LE Almaguer-Mederos, MV Halbach, ... Neurobiology of Disease 152, 105289, 2021 | 28 | 2021 |
| Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated MV Halbach, T Stehning, E Damrath, M Jendrach, NE Şen, AN Başak, ... PLoS One 10 (3), e0121089, 2015 | 25 | 2015 |
| In human and mouse spino-cerebellar tissue, ataxin-2 expansion affects ceramide-sphingomyelin metabolism NE Sen, A Arsovic, D Meierhofer, S Brodesser, C Oberschmidt, ... International journal of molecular sciences 20 (23), 5854, 2019 | 22 | 2019 |
| Mid-Gestation lethality of Atxn2l-Ablated Mice J Key, PN Harter, NE Sen, E Gradhand, G Auburger, S Gispert International journal of molecular sciences 21 (14), 5124, 2020 | 17 | 2020 |
| SerThr-PhosphoProteome of brain from aged PINK1-KO+ A53T-SNCA mice reveals pT1928-MAP1B and pS3781-ANK2 deficits, as hub between autophagy and synapse changes G Auburger, S Gispert, S Torres-Odio, M Jendrach, N Brehm, ... International journal of molecular sciences 20 (13), 3284, 2019 | 17 | 2019 |
| Systematic surveys of iron homeostasis mechanisms reveal ferritin superfamily and nucleotide surveillance regulation to be modified by PINK1 absence J Key, NE Sen, A Arsović, S Krämer, R Hülse, NN Khan, D Meierhofer, ... Cells 9 (10), 2229, 2020 | 14 | 2020 |
| Mouse ataxin-2 expansion downregulates CamKII and other calcium signaling factors, impairing granule—Purkinje neuron synaptic strength A Arsović, MV Halbach, J Canet-Pons, D Esen-Sehir, C Döring, ... International journal of molecular sciences 21 (18), 6673, 2020 | 14 | 2020 |
| The complex genetic landscape of hereditary ataxias in Turkey and implications in clinical practice A Vural, G Şimşir, Ş Tekgül, C Koçoğlu, F Akcimen, E Kartal, NE Şen, ... Movement Disorders 36 (7), 1676-1688, 2021 | 12 | 2021 |
| Revisiting the complex architecture of ALS in Turkey: Expanding genotypes, shared phenotypes, molecular networks, and a public variant database C Tunca, T Şeker, F Akcimen, C Coşkun, E Bayraktar, R Palvadeau, S Zor, ... Human mutation 41 (8), e7-e45, 2020 | 12 | 2020 |
| Poly (A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates S Boeynaems, Y Dorone, Y Zhuang, V Shabardina, G Huang, A Marian, ... Molecular cell 83 (12), 2020-2034. e6, 2023 | 10 | 2023 |
| PINK1 and Ataxin-2 as modifiers of growth NE Sen, S Gispert, G Auburger Oncotarget 8 (20), 32382, 2017 | 7 | 2017 |
| In spino-cerebellar tissue, Ataxin-2 expansion affects ceramide-sphingomyelin metabolism NE Sen, A Arsovic, D Meierhofer, S Brodesser, C Oberschmidt, ... Preprints, 2019 | 1 | 2019 |
| Iron depletion reduces Abce1 transcripts while inducing the mitophagy factors Pink1 and Parkin J Key, NE Sen, A Arsovic, S Krämer, R Hülse, S Gispert-Sanchez, ... Preprints, 2019 | 1 | 2019 |
