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Lourdes Santana
Lourdes Santana
Profesora de Química Farmacéutica, Universidad de Santiago de Compostela
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Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity
F Borges, F Roleira, N Milhazes, L Santana, E Uriarte
Current medicinal chemistry 12 (8), 887-916, 2005
12082005
Medicinal chemistry and bioinformatics-current trends in drugs discovery with networks topological indices
H Gonzalez-Diaz, S Vilar, L Santana, E Uriarte
Current topics in medicinal chemistry 7 (10), 1015-1029, 2007
3732007
Proteomics, networks and connectivity indices
H González‐Díaz, Y González‐Díaz, L Santana, FM Ubeira, E Uriarte
Proteomics 8 (4), 750-778, 2008
3082008
Coumarins—an important class of phytochemicals
MJ Matos, L Santana, E Uriarte, OA Abreu, E Molina, EG Yordi
Phytochemicals-isolation, characterisation and role in human health 25, 533-538, 2015
2512015
Drug—drug interaction through molecular structure similarity analysis
S Vilar, R Harpaz, E Uriarte, L Santana, R Rabadan, C Friedman
Journal of the American Medical Informatics Association 19 (6), 1066-1074, 2012
2312012
Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity
L Santana, E Uriarte, F Roleira, N Milhazes, F Borges
Current medicinal chemistry 11 (24), 3239-3261, 2004
2272004
Similarity-based modeling in large-scale prediction of drug-drug interactions
S Vilar, E Uriarte, L Santana, T Lorberbaum, G Hripcsak, C Friedman, ...
Nature protocols 9 (9), 2147-2163, 2014
2242014
A novel approach for the virtual screening and rational design of anticancer compounds
E Estrada, E Uriarte, A Montero, M Teijeira, L Santana, E De Clercq
Journal of medicinal chemistry 43 (10), 1975-1985, 2000
2232000
Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin–resveratrol hybrids
S Vilar, E Quezada, L Santana, E Uriarte, M Yánez, N Fraiz, C Alcaide, ...
Bioorganic & Medicinal Chemistry Letters 16 (2), 257-261, 2006
2032006
A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins
L Santana, E Uriarte, H González-Díaz, G Zagotto, R Soto-Otero, ...
Journal of medicinal chemistry 49 (3), 1149-1156, 2006
1902006
Potential pharmacological uses of chalcones: a patent review (from June 2011–2014)
MJ Matos, S Vazquez-Rodriguez, E Uriarte, L Santana
Expert opinion on therapeutic patents 25 (3), 351-366, 2015
1682015
Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors
MJ Matos, C Teran, Y Perez-Castillo, E Uriarte, L Santana, D Vina
Journal of medicinal chemistry 54 (20), 7127-7137, 2011
1682011
A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors
MJ Matos, D Viña, E Quezada, C Picciau, G Delogu, F Orallo, L Santana, ...
Bioorganic & medicinal chemistry letters 19 (12), 3268-3270, 2009
1562009
Quantitative structure− activity relationship and complex network approach to monoamine oxidase A and B inhibitors
L Santana, H Gonzalez-Diaz, E Quezada, E Uriarte, M Yanez, D Vina, ...
Journal of medicinal chemistry 51 (21), 6740-6751, 2008
1452008
Simple coumarins: privileged scaffolds in medicinal chemistry
MFM Borges, FMF Roleira, N Milhazes, EU Villare, LS Penin
Frontiers in medicinal chemistry 4, 23-85, 2010
1392010
Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors
MJ Matos, D Viña, C Picciau, F Orallo, L Santana, E Uriarte
Bioorganic & medicinal chemistry letters 19 (17), 5053-5055, 2009
1312009
Detection of drug-drug interactions by modeling interaction profile fingerprints
S Vilar, E Uriarte, L Santana, NP Tatonetti, C Friedman
PloS one 8 (3), e58321, 2013
1282013
3-Substituted coumarins as dual inhibitors of AChE and MAO for the treatment of Alzheimer's disease
D Vina, MJ Matos, M Yáñez, L Santana, E Uriarte
MedChemComm 3 (2), 213-218, 2012
1232012
Synthesis and vasorelaxant activity of new coumarin and furocoumarin derivatives
M Campos-Toimil, F Orallo, L Santana, E Uriarte
Bioorganic & medicinal chemistry letters 12 (5), 783-786, 2002
1172002
Tyrosinase inhibitor activity of coumarin-resveratrol hybrids
A Fais, M Corda, B Era, MB Fadda, MJ Matos, E Quezada, L Santana, ...
Molecules 14 (7), 2514-2520, 2009
1112009
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