| Structural basis for cooperative function of Mettl3 and Mettl14 methyltransferases P Wang, KA Doxtader, Y Nam Molecular cell 63 (2), 306-317, 2016 | 958 | 2016 |
| Structure of a complex of the ATPase SecA and the protein-translocation channel J Zimmer, Y Nam, TA Rapoport Nature 455 (7215), 936-943, 2008 | 568 | 2008 |
| Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes Y Nam, P Sliz, L Song, JC Aster, SC Blacklow Cell 124 (5), 973-983, 2006 | 522 | 2006 |
| Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling AP Weng, Y Nam, MS Wolfe, WS Pear, JD Griffin, SC Blacklow, JC Aster Molecular and cellular biology, 2003 | 510 | 2003 |
| Structure of human O-GlcNAc transferase and its complex with a peptide substrate MB Lazarus, Y Nam, J Jiang, P Sliz, S Walker Nature 469 (7331), 564-567, 2011 | 485 | 2011 |
| Molecular basis for interaction of let-7 microRNAs with Lin28 Y Nam, C Chen, RI Gregory, JJ Chou, P Sliz Cell 147 (5), 1080-1091, 2011 | 459 | 2011 |
| Structural requirements for assembly of the CSLˇ intracellular Notch1ˇ Mastermind-like 1 transcriptional activation complex Y Nam, AP Weng, JC Aster, SC Blacklow Journal of Biological Chemistry 278 (23), 21232-21239, 2003 | 277 | 2003 |
| Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription Y Nam, P Sliz, WS Pear, JC Aster, SC Blacklow Proceedings of the National Academy of Sciences 104 (7), 2103-2108, 2007 | 189 | 2007 |
| Structural basis for regulation of METTL16, an S-adenosylmethionine homeostasis factor KA Doxtader, P Wang, AM Scarborough, D Seo, NK Conrad, Y Nam Molecular cell 71 (6), 1001-1011. e4, 2018 | 174 | 2018 |
| A role for the two-helix finger of the SecA ATPase in protein translocation KJ Erlandson, SBM Miller, Y Nam, AR Osborne, J Zimmer, TA Rapoport Nature 455 (7215), 984, 2008 | 174 | 2008 |
| Notch signaling as a therapeutic target Y Nam, JC Aster, SC Blacklow Current opinion in chemical biology 6 (4), 501-509, 2002 | 167 | 2002 |
| METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis R Su, L Dong, Y Li, M Gao, PC He, W Liu, J Wei, Z Zhao, L Gao, L Han, ... Nature cell biology 24 (2), 205-216, 2022 | 164 | 2022 |
| Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1 MY Chiang, ML Xu, G Histen, O Shestova, M Roy, Y Nam, SC Blacklow, ... Molecular and cellular biology 26 (16), 6261-6271, 2006 | 123 | 2006 |
| Data publication with the structural biology data grid supports live analysis PA Meyer, S Socias, J Key, E Ransey, EC Tjon, A Buschiazzo, M Lei, ... Nature communications 7 (1), 10882, 2016 | 106 | 2016 |
| Small-molecule inhibitors disrupt let-7 oligouridylation and release the selective blockade of let-7 processing by LIN28 L Wang, RG Rowe, A Jaimes, C Yu, Y Nam, DS Pearson, J Zhang, X Xie, ... Cell reports 23 (10), 3091-3101, 2018 | 101 | 2018 |
| Cryo-EM structures of human Drosha and DGCR8 in complex with primary microRNA AC Partin, K Zhang, BC Jeong, E Herrell, S Li, W Chiu, Y Nam Molecular cell 78 (3), 411-422. e4, 2020 | 85 | 2020 |
| LIN28 zinc knuckle domain is required and sufficient to induce let-7 oligouridylation L Wang, Y Nam, AK Lee, C Yu, K Roth, C Chen, EM Ransey, P Sliz Cell reports 18 (11), 2664-2675, 2017 | 76 | 2017 |
| Conformational locking upon cooperative assembly of notch transcription complexes SH Choi, TE Wales, Y Nam, DJ O'Donovan, P Sliz, JR Engen, ... Structure 20 (2), 340-349, 2012 | 72 | 2012 |
| Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs AC Partin, TD Ngo, E Herrell, BC Jeong, G Hon, Y Nam Nature communications 8 (1), 1737, 2017 | 62 | 2017 |
| RNA specificity and autoregulation of DDX17, a modulator of microRNA biogenesis TD Ngo, AC Partin, Y Nam Cell reports 29 (12), 4024-4035. e5, 2019 | 38 | 2019 |
Piotr Sliz, PhDHarvard Medical SchoolVerified email at hkl.hms.harvard.edu
