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Daniel J Cua
Daniel J Cua
VP, Immunology Janssen Research & Development
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
II Ivanov, BS McKenzie, L Zhou, CE Tadokoro, A Lepelley, JJ Lafaille, ...
Cell 126 (6), 1121-1133, 2006
64862006
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
CL Langrish, Y Chen, WM Blumenschein, J Mattson, B Basham, ...
The Journal of experimental medicine 201 (2), 233-240, 2005
53992005
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
DJ Cua, J Sherlock, YI Chen, CA Murphy, B Joyce, B Seymour, L Lucian, ...
Nature 421 (6924), 744-748, 2003
37922003
Development, cytokine profile and function of human interleukin 17–producing helper T cells
NJ Wilson, K Boniface, JR Chan, BS McKenzie, WM Blumenschein, ...
Nature immunology 8 (9), 950-957, 2007
26012007
Divergent pro-and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
CA Murphy, CL Langrish, Y Chen, W Blumenschein, T McClanahan, ...
The Journal of experimental medicine 198 (12), 1951-1957, 2003
22372003
IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6
D Yen, J Cheung, H Scheerens, F Poulet, T McClanahan, B McKenzie, ...
The Journal of clinical investigation 116 (5), 1310-1316, 2006
19952006
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology
MJ McGeachy, KS Bak-Jensen, YI Chen, CM Tato, W Blumenschein, ...
Nature immunology 8 (12), 1390-1397, 2007
19352007
Innate IL-17-producing cells: the sentinels of the immune system
DJ Cua, CM Tato
Nature Reviews Immunology 10 (7), 479-489, 2010
18712010
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
K Sato, A Suematsu, K Okamoto, A Yamaguchi, Y Morishita, Y Kadono, ...
The Journal of experimental medicine 203 (12), 2673-2682, 2006
18152006
Generation of pathogenic TH17 cells in the absence of TGF-β signalling
K Ghoreschi, A Laurence, XP Yang, CM Tato, MJ McGeachy, JE Konkel, ...
Nature 467 (7318), 967-971, 2010
17042010
The IL-23–IL-17 immune axis: from mechanisms to therapeutic testing
SL Gaffen, R Jain, AV Garg, DJ Cua
Nature reviews immunology 14 (9), 585-600, 2014
15312014
In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2 …
FJ Barrat, DJ Cua, A Boonstra, DF Richards, C Crain, HF Savelkoul, ...
The Journal of experimental medicine 195 (5), 603-616, 2002
15112002
Fate mapping of IL-17-producing T cells in inflammatory responses
K Hirota, JH Duarte, M Veldhoen, E Hornsby, Y Li, DJ Cua, H Ahlfors, ...
Nature immunology 12 (3), 255-263, 2011
13172011
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
MJ McGeachy, Y Chen, CM Tato, A Laurence, B Joyce-Shaikh, ...
Nature immunology 10 (3), 314-324, 2009
12742009
IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4CD8 entheseal resident T cells
JP Sherlock, B Joyce-Shaikh, SP Turner, CC Chao, M Sathe, J Grein, ...
Nature medicine 18 (7), 1069-1076, 2012
11562012
Interleukin-23 drives innate and T cell–mediated intestinal inflammation
S Hue, P Ahern, S Buonocore, MC Kullberg, DJ Cua, BS McKenzie, ...
The Journal of experimental medicine 203 (11), 2473-2483, 2006
10822006
Understanding the IL-23–IL-17 immune pathway
BS McKenzie, RA Kastelein, DJ Cua
Trends in immunology 27 (1), 17-23, 2006
10622006
Interleukin-17-producing γδ T cells selectively expand in response to pathogen products and environmental signals
B Martin, K Hirota, DJ Cua, B Stockinger, M Veldhoen
Immunity 31 (2), 321-330, 2009
10192009
IL‐12 and IL‐23: master regulators of innate and adaptive immunity
CL Langrish, BS McKenzie, NJ Wilson, R de Waal Malefyt, RA Kastelein, ...
Immunological reviews 202 (1), 96-105, 2004
9672004
Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury
T Shichita, Y Sugiyama, H Ooboshi, H Sugimori, R Nakagawa, I Takada, ...
Nature medicine 15 (8), 946-950, 2009
9482009
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