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Adriana Ordóñez (0000-0003-4239-459X)
Adriana Ordóñez (0000-0003-4239-459X)
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
K Yusa, ST Rashid, H Strick-Marchand, I Varela, PQ Liu, DE Paschon, ...
Nature 478 (7369), 391-394, 2011
8152011
Antithrombin Cambridge II (A384S): an underestimated genetic risk factor for venous thrombosis
J Corral, D Hernandez-Espinosa, JM Soria, R Gonzalez-Conejero, ...
Blood 109 (10), 4258-4263, 2007
1392007
Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1‐antitrypsin deficiency
A Ordóñez, EL Snapp, L Tan, E Miranda, SJ Marciniak, DA Lomas
Hepatology 57 (5), 2049-2060, 2013
1232013
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells
HP Harding, A Ordonez, F Allen, L Parts, AJ Inglis, RL Williams, D Ron
Elife 8, e50149, 2019
1182019
Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells
AA Wilson, L Ying, M Liesa, CP Segeritz, JA Mills, SS Shen, J Jean, ...
Stem cell reports 4 (5), 873-885, 2015
992015
Circulating polymers in α1-antitrypsin deficiency
L Tan, JA Dickens, DL DeMeo, E Miranda, J Perez, ST Rashid, J Day, ...
European Respiratory Journal 43 (5), 1501-1504, 2014
752014
A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity
A Ordóñez, J Pérez, L Tan, JA Dickens, N Motamedi-Shad, JA Irving, ...
The FASEB Journal 29 (6), 2667, 2015
572015
Functional consequences of the prothrombotic SERPINC1 rs2227589 polymorphism on antithrombin levels
AI Antón, R Teruel, J Corral, A Minano, I Martínez-Martínez, A Ordóñez, ...
haematologica 94 (4), 589, 2009
572009
Unravelling the twists and turns of the serpinopathies
BD Roussel, JA Irving, UI Ekeowa, D Belorgey, I Haq, A Ordóñez, ...
The FEBS journal 278 (20), 3859-3867, 2011
542011
hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency
CP Segeritz, ST Rashid, MC de Brito, MP Serra, A Ordonez, CM Morell, ...
Journal of hepatology 69 (4), 851-860, 2018
502018
AB0 blood group and risk of venous or arterial thrombosis in carriers of factor V Leiden or prothrombin G20210A polymorphisms
A Miñano, A Ordóñez, F España, JR González-Porras, R Lecumberri, ...
haematologica 93 (5), 729-734, 2008
502008
p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress
SE Thomas, E Malzer, A Ordoñez, LE Dalton, E Liniker, DC Crowther, ...
Journal of Biological Chemistry 288 (11), 7606-7617, 2013
482013
Polymers of Z α1-antitrypsin are secreted in cell models of disease
A Fra, F Cosmi, A Ordoñez, R Berardelli, J Perez, NA Guadagno, L Corda, ...
European Respiratory Journal 47 (3), 1005-1009, 2016
462016
Effect of citrullination on the function and conformation of antithrombin
A Ordonez, I Martínez‐Martínez, FJ Corrales, C Miqueo, A Miñano, ...
The FEBS Journal 276 (22), 6763-6772, 2009
462009
Antithrombin Cambridge II (A384S) supports a role for antithrombin deficiency in arterial thrombosis
V Roldán, A Ordoñez, F Marín, E Zorio, JM Soria, A Miñano, F España, ...
Thrombosis and haemostasis 101 (03), 483-486, 2009
462009
Development of a small molecule that corrects misfolding and increases secretion of Z α1‐antitrypsin
DA Lomas, JA Irving, C Arico‐Muendel, S Belyanskaya, A Brewster, ...
EMBO Molecular Medicine 13 (3), e13167, 2021
422021
The serpinopathies: studying serpin polymerization in vivo
JA Irving, UI Ekeowa, D Belorgey, I Haq, B Gooptu, E Miranda, J Pérez, ...
Methods in enzymology 501, 421-466, 2011
392011
Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin
EFA van ‘t Wout, JA Dickens, A van Schadewijk, I Haq, HF Kwok, ...
Human molecular genetics 23 (4), 929-941, 2014
382014
Antithrombin Murcia (K241E) causing antithrombin deficiency: a possible role for altered glycosylation
I Martínez-Martínez, A Ordóñez, J Navarro-Fernández, Á Pérez-Lara, ...
haematologica 95 (8), 1358, 2010
382010
Poly (ADP-ribose) polymerase-1 inhibition increases expression of heat shock proteins and attenuates heat stroke-induced liver injury
RA Mota, D Hernández-Espinosa, L Galbis-Martinez, A Ordoñez, ...
Critical care medicine 36 (2), 526-534, 2008
312008
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