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P J Michael Deans
P J Michael Deans
Verified email at yale.edu
Title
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Cited by
Year
Synergistic effects of common schizophrenia risk variants
N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ...
Nature genetics 51 (10), 1475-1485, 2019
2032019
Neuronal impact of patient-specific aberrant NRXN1α splicing
E Flaherty, S Zhu, N Barretto, E Cheng, PJM Deans, MB Fernando, ...
Nature genetics 51 (12), 1679-1690, 2019
1042019
Psychosis risk candidate ZNF804A localizes to synapses and regulates neurite formation and dendritic spine structure
PJM Deans, P Raval, KJ Sellers, NJF Gatford, S Halai, RRR Duarte, ...
Biological psychiatry 82 (1), 49-61, 2017
932017
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection
K Dobrindt, DA Hoagland, C Seah, B Kassim, CP O'Shea, A Murphy, ...
Stem Cell Reports 16 (3), 505-518, 2021
512021
Modeling gene× environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression
C Seah, MS Breen, T Rusielewicz, HN Bader, C Xu, CJ Hunter, ...
Nature neuroscience 25 (11), 1434-1445, 2022
262022
Characterisation of neurons derived from a cortical human neural stem cell line CTX0E16
GW Anderson, PJM Deans, RDT Taylor, P Raval, D Chen, H Lowder, ...
Stem cell research & therapy 6, 1-20, 2015
232015
Applying stem cells and CRISPR engineering to uncover the etiology of schizophrenia
PJM Deans, KJ Brennand
Current opinion in neurobiology 69, 193-201, 2021
172021
Analysis framework and experimental design for evaluating synergy-driving gene expression
N Schrode, C Seah, PJM Deans, G Hoffman, KJ Brennand
Nature protocols 16 (2), 812-840, 2021
92021
Convergent impact of schizophrenia risk genes
KG Townsley, A Li, PJM Deans, JF Fullard, A Yu, S Cartwright, W Zhang, ...
bioRxiv, 2022.03. 29.486286, 2022
72022
Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells
A Bhat, H Irizar, ACM Couch, P Raval, RRR Duarte, LD Polit, B Hanger, ...
Brain, Behavior, and Immunity 105, 82-97, 2022
62022
Neuroligin-3 and neuroligin-4X form nanoscopic clusters and regulate growth cone organization and size
NJF Gatford, PJM Deans, RRR Duarte, G Chennell, KJ Sellers, P Raval, ...
Human Molecular Genetics 31 (5), 674-691, 2022
62022
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
A Li, S Cartwright, A Yu, SM Ho, N Schrode, PJM Deans, MR Matos, ...
STAR protocols 2 (2), 100580, 2021
52021
Non-additive effects of schizophrenia risk genes reflect convergent downstream function
PJM Deans, C Seah, J Johnson, JG Gonzalez, K Townsley, E Cao, ...
medRxiv, 2023
42023
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection (preprint)
K Dobrindt, DA Hoagland, C Seah, B Kassim, M Iskhakova, M Fernando, ...
22020
Nanoscopic Clustering of Neuroligin-3 and Neuroligin-4X Regulates Growth Cone Organization and Size
NJF Gatford, PJ Michael Deans, RRR Duarte, G Chennell, P Raval, ...
bioRxiv, 546499, 2019
22019
O10. 7. Investigating the mechanisms underlying the beneficial effects of estrogens in schizophrenia
PJ Michael Deans, C Shum, L Perfect, M Conforti, R Duarte, ...
Schizophrenia Bulletin 44 (suppl_1), S105-S105, 2018
22018
MASSIVELY PARALLEL CHARACTERIZATION OF CONTEXT SPECIFIC REGULATORY RISK ELEMENTS ACROSS PSYCHIATRIC DISORDERS IN HUMAN-INDUCED PLURIPOTENT STEM CELL-DERIVED GLUTAMATERGIC NEURONS
K Townsley, A Sen, J Lee, PJM Deans, M Jia, M Fernandez-Garcia, ...
European Neuropsychopharmacology 75, S7-S8, 2023
2023
Better together: Non-additive interactions between schizophrenia risk genes
PJM Deans, KJ Brennand
Cell Genomics 3 (9), 2023
2023
Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes
SK Powell, W Liao, C O’Shea, S Kammourh, S Ghorbani, R Rigat, R Elahi, ...
bioRxiv, 2023
2023
Common genetic variation impacts molecular stress response in the brain
C Seah, R Singer, PJM Deans, H Bader, T Rusielewicz, EM Hicks, ...
bioRxiv, 2023.12. 27.573459, 2023
2023
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