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Nikolaos A Patsopoulos, MD PhD
Nikolaos A Patsopoulos, MD PhD
Novartis Institutes for BioMedical Research
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Nature 476 (7359), 214-219, 2011
29432011
Genetic and epigenetic fine mapping of causal autoimmune disease variants
KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ...
Nature 518 (7539), 337-343, 2015
19092015
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
13472018
International Multiple Sclerosis Genetics Consortium (IMSGC); Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC). Analysis of …
AH Beecham, NA Patsopoulos, DK Xifara, MF Davis, A Kemppinen, ...
Nat Genet 45 (11), 1353-1360, 2013
1337*2013
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
12932015
Uncertainty in heterogeneity estimates in meta-analyses
JPA Ioannidis, NA Patsopoulos, E Evangelou
Bmj 335 (7626), 914-916, 2007
11262007
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
International Multiple Sclerosis Genetics Consortium*†, ANZgene, ...
Science 365 (6460), eaav7188, 2019
913*2019
A pragmatic view on pragmatic trials
NA Patsopoulos
Dialogues in clinical neuroscience 13 (2), 217-224, 2011
8692011
Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation
NA Patsopoulos, E Evangelou, JPA Ioannidis
International journal of epidemiology 37 (5), 1148-1157, 2008
8682008
Relative citation impact of various study designs in the health sciences
NA Patsopoulos, AA Analatos, JPA Ioannidis
Jama 293 (19), 2362-2366, 2005
5872005
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
5702018
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes
T Raj, K Rothamel, S Mostafavi, C Ye, MN Lee, JM Replogle, T Feng, ...
Science 344 (6183), 519-523, 2014
5302014
Reasons or excuses for avoiding meta-analysis in forest plots
JPA Ioannidis, NA Patsopoulos, HR Rothstein
Bmj 336 (7658), 1413-1415, 2008
4812008
Genome‐wide meta‐analysis identifies novel multiple sclerosis susceptibility loci
NA Patsopoulos, ...
Annals of neurology 70 (6), 897-912, 2011
399*2011
Class II HLA interactions modulate genetic risk for multiple sclerosis
Nature genetics 47 (10), 1107-1113, 2015
3812015
Heterogeneity in meta-analyses of genome-wide association investigations
JPA Ioannidis, NA Patsopoulos, E Evangelou
PloS one 2 (9), e841, 2007
3612007
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects
NA Patsopoulos, LF Barcellos, RQ Hintzen, C Schaefer, CM Van Duijn, ...
PLoS genetics 9 (11), e1003926, 2013
3602013
Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types
S Chun, A Casparino, NA Patsopoulos, DC Croteau-Chonka, BA Raby, ...
Nature genetics 49 (4), 600-605, 2017
2202017
Postmortem cortex samples identify distinct molecular subtypes of ALS: retrotransposon activation, oxidative stress, and activated glia
OH Tam, NV Rozhkov, R Shaw, D Kim, I Hubbard, S Fennessey, N Propp, ...
Cell reports 29 (5), 1164-1177. e5, 2019
2142019
Genetic susceptibility for Alzheimer disease neuritic plaque pathology
JM Shulman, K Chen, BT Keenan, LB Chibnik, A Fleisher, P Thiyyagura, ...
JAMA neurology 70 (9), 1150-1157, 2013
1862013
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Artikelen 1–20