Lawrence Heisler
Lawrence Heisler
Ontario Institute of Cancer Research
Verified email at
Cited by
Cited by
Genotype to phenotype: a complex problem
RD Dowell, O Ryan, A Jansen, D Cheung, S Agarwala, T Danford, ...
Science 328 (5977), 469-469, 2010
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ...
Nature 538 (7625), 378-382, 2016
Genomic hallmarks of localized, non-indolent prostate cancer
M Fraser, VY Sabelnykova, TN Yamaguchi, LE Heisler, J Livingstone, ...
Nature 541 (7637), 359-364, 2017
Prediction of acute myeloid leukaemia risk in healthy individuals
S Abelson, G Collord, SWK Ng, O Weissbrod, NM Cohen, E Niemeyer, ...
Nature 559 (7714), 400-404, 2018
Quantitative phenotyping via deep barcode sequencing
AM Smith, LE Heisler, J Mellor, F Kaper, MJ Thompson, M Chee, FP Roth, ...
Genome research 19 (10), 1836-1842, 2009
Tracing the origins of relapse in acute myeloid leukaemia to stem cells
LI Shlush, A Mitchell, L Heisler, S Abelson, SWK Ng, A Trotman-Grant, ...
Nature 547 (7661), 104-108, 2017
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
TS Alioto, I Buchhalter, S Derdak, B Hutter, MD Eldridge, E Hovig, ...
Nature communications 6 (1), 1-13, 2015
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples
AM Smith, LE Heisler, RP St. Onge, E Farias-Hesson, IM Wallace, ...
Nucleic acids research 38 (13), e142-e142, 2010
Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor
LE Heisler, A Evangelou, AM Lew, J Trachtenberg, HP Elsholtz, TJ Brown
Molecular and cellular endocrinology 126 (1), 59-73, 1997
Mapping the cellular response to small molecules using chemogenomic fitness signatures
AY Lee, RPS Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ...
Science 344 (6180), 208-211, 2014
Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic …
MD Hyrcza, C Kovacs, M Loutfy, R Halpenny, L Heisler, S Yang, O Wilkins, ...
Journal of virology 81 (7), 3477-3486, 2007
Genomic DNA functions as a universal external standard in quantitative real-time PCR
JJ Yun, LE Heisler, IIL Hwang, O Wilkins, SK Lau, M Hyrcza, ...
Nucleic acids research 34 (12), e85-e85, 2006
Genomic DNA functions as a universal external standard in quantitative real-time PCR
JJ Yun, LE Heisler, IIL Hwang, O Wilkins, SK Lau, M Hyrcza, ...
Nucleic acids research 34 (12), e85-e85, 2006
Widespread and functional RNA circularization in localized prostate cancer
S Chen, V Huang, X Xu, J Livingstone, F Soares, J Jeon, Y Zeng, JT Hua, ...
Cell 176 (4), 831-843. e22, 2019
Molecular landmarks of tumor hypoxia across cancer types
V Bhandari, C Hoey, LY Liu, E Lalonde, J Ray, J Livingstone, R Lesurf, ...
Nature genetics 51 (2), 308-318, 2019
CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome
LE Heisler, D Torti, PC Boutros, J Watson, C Chan, N Winegarden, ...
Nucleic acids research 33 (9), 2952-2961, 2005
Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories
RA Taylor, M Fraser, J Livingstone, SMG Espiritu, H Thorne, V Huang, ...
Nature communications 8 (1), 1-10, 2017
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ...
Nature 572 (7767), 67-73, 2019
The evolutionary landscape of localized prostate cancers drives clinical aggression
SMG Espiritu, LY Liu, Y Rubanova, V Bhandari, EM Holgersen, LM Szyca, ...
Cell 173 (4), 1003-1013. e15, 2018
Multiple means to the same end: the genetic basis of acquired stress resistance in yeast
DB Berry, Q Guan, J Hose, S Haroon, M Gebbia, LE Heisler, C Nislow, ...
PLoS Genet 7 (11), e1002353, 2011
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