| European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia JS Lucas, A Barbato, SA Collins, M Goutaki, L Behan, D Caudri, S Dell, ... European Respiratory Journal 49 (1), 2017 | 617 | 2017 |
| Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities VH Castleman, L Romio, R Chodhari, RA Hirst, SCP de Castro, KA Parker, ... The American Journal of Human Genetics 84 (2), 197-209, 2009 | 364 | 2009 |
| The role of pneumolysin in pneumococcal pneumonia and meningitis RA Hirst, A Kadioglu, C O'callaghan, PW Andrew Clinical & Experimental Immunology 138 (2), 195-201, 2004 | 321 | 2004 |
| Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia HM Mitchison, M Schmidts, NT Loges, J Freshour, A Dritsoula, RA Hirst, ... Nature genetics 44 (4), 381-389, 2012 | 307 | 2012 |
| MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia M Boon, J Wallmeier, L Ma, NT Loges, M Jaspers, H Olbrich, ... Nature communications 5 (1), 4418, 2014 | 244 | 2014 |
| Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma B Thomas, A Rutman, RA Hirst, P Haldar, AJ Wardlaw, J Bankart, ... Journal of Allergy and Clinical Immunology 126 (4), 722-729. e2, 2010 | 228 | 2010 |
| Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1 CAM Lopes, SL Prosser, L Romio, RA Hirst, C O'Callaghan, AS Woolf, ... Journal of cell science 124 (4), 600-612, 2011 | 185 | 2011 |
| Evidence of respiratory syncytial virus spread by aerosol. Time to revisit infection control strategies? H Kulkarni, CM Smith, DDH Lee, RA Hirst, AJ Easton, C O’Callaghan American journal of respiratory and critical care medicine 194 (3), 308-316, 2016 | 159 | 2016 |
| Respiratory syncytial virus increases the virulence of Streptococcus pneumoniae by binding to penicillin binding protein 1a. A new paradigm in respiratory infection CM Smith, S Sandrini, S Datta, P Freestone, S Shafeeq, P Radhakrishnan, ... American journal of respiratory and critical care medicine 190 (2), 196-207, 2014 | 145 | 2014 |
| Streptococcus pneumoniae Deficient in Pneumolysin or Autolysin Has Reduced Virulence in Meningitis RA Hirst, B Gosai, A Rutman, CJ Guerin, P Nicotera, PW Andrew, ... The Journal of infectious diseases 197 (5), 744-751, 2008 | 142 | 2008 |
| Relative Roles of Pneumolysin and Hydrogen Peroxide from Streptococcus pneumoniae in Inhibition of Ependymal Ciliary Beat Frequency RA Hirst, KS Sikand, A Rutman, TJ Mitchell, PW Andrew, C O'Callaghan Infection and immunity 68 (3), 1557-1562, 2000 | 140 | 2000 |
| Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid RA Hirst, CL Jackson, JL Coles, G Williams, A Rutman, PM Goggin, ... PloS one 9 (2), e89675, 2014 | 131 | 2014 |
| Hypoxia upregulates neutrophil degranulation and potential for tissue injury K Hoenderdos, KM Lodge, RA Hirst, C Chen, SGC Palazzo, ... Thorax 71 (11), 1030-1038, 2016 | 120 | 2016 |
| Ciliated air-liquid cultures as an aid to diagnostic testing of primary ciliary dyskinesia RA Hirst, A Rutman, G Williams, C O'Callaghan Chest 138 (6), 1441-1447, 2010 | 118 | 2010 |
| Pharmacology and potential therapeutic uses of cannabis. RA Hirst, DG Lambert, WG Notcutt British journal of anaesthesia 81 (1), 77-84, 1998 | 112 | 1998 |
| International consensus guideline for reporting transmission electron microscopy results in the diagnosis of primary ciliary dyskinesia (BEAT PCD TEM Criteria) A Shoemark, M Boon, C Brochhausen, Z Bukowy-Bieryllo, MM De Santi, ... European Respiratory Journal 55 (4), 2020 | 110 | 2020 |
| Ciliary dyskinesia is an early feature of respiratory syncytial virus infection CM Smith, H Kulkarni, P Radhakrishnan, A Rutman, MJ Bankart, ... European Respiratory Journal 43 (2), 485-496, 2014 | 106 | 2014 |
| Mutations in outer dynein arm heavy chain DNAH9 cause motile cilia defects and situs inversus MR Fassad, A Shoemark, M Legendre, RA Hirst, F Koll, P Le Borgne, ... The American Journal of Human Genetics 103 (6), 984-994, 2018 | 105 | 2018 |
| ciliaFA: a research tool for automated, high-throughput measurement of ciliary beat frequency using freely available software CM Smith, J Djakow, RC Free, P Djakow, R Lonnen, G Williams, ... Cilia 1, 1-7, 2012 | 102 | 2012 |
| Pseudomonas aeruginosa-catecholamine inotrope interactions: a contributory factor in the development of ventilator-associated pneumonia? PP Freestone, RA Hirst, SM Sandrini, F Sharaff, H Fry, S Hyman, ... Chest 142 (5), 1200-1210, 2012 | 101 | 2012 |
Christopher O'CallaghanProfessor of Respiratory & Paediatric Medicine, UCL Great Ormond Street Institute of Child HealthVerified email at ucl.ac.uk
