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Yan-Yi Chan
Yan-Yi Chan
Verified email at stanford.edu
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Year
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
A Czechowicz, R Palchaudhuri, A Scheck, YU Hu, J Hoggatt, B Saez, ...
Nature communications 10 (1), 617, 2019
1522019
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells
JL Gori, JM Butler, YY Chan, D Chandrasekaran, MG Poulos, M Ginsberg, ...
The Journal of clinical investigation 125 (3), 1243-1254, 2015
1262015
A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates
S Radtke, JE Adair, MA Giese, YY Chan, ZK Norgaard, M Enstrom, ...
Science translational medicine 9 (414), eaan1145, 2017
1042017
Purification of human CD34+ CD90+ HSCs reduces target cell population and improves lentiviral transduction for gene therapy
S Radtke, D Pande, M Cui, AM Perez, YY Chan, M Enstrom, S Schmuck, ...
Molecular Therapy-Methods & Clinical Development 18, 679-691, 2020
342020
MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells
S Radtke, YY Chan, TR Sippel, HP Kiem, A Rongvaux
Experimental hematology 70, 31-41. e1, 2019
222019
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures
KJ Igarashi, I Kucinski, YY Chan, TK Tan, HM Khoo, D Kealy, J Bhadury, ...
Blood Advances 7 (14), 3366-3377, 2023
72023
Selective hematopoietic stem cell ablation using CD117-antibody-drugconjugates enables safe and effective transplantation with immunity preservation. Nat. Commun. 10, 617
A Czechowicz, R Palchaudhuri, A Scheck, Y Hu, J Hoggatt, B Saez, ...
72019
Sort-purification of human CD34+CD90+ cells reduces target cell population and improves lentiviral transduction
S Radtke, D Pande, M Cui, AM Perez, YY Chan, M Enstrom, S Schmuck, ...
bioRxiv, 850479, 2019
42019
Non-genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia
YY Chan, PY Ho, L Swartzrock, M Rayburn, R Nofal, S Thongthip, ...
Transplantation and Cellular Therapy 29 (3), 164. e1-164. e9, 2023
22023
Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ+ T-Cell …
R Agarwal, A Bertaina, CF Soco, G Saini, N Kunte, L Hiroshima, YY Chan, ...
Blood 142, 229, 2023
12023
A novel highly conserved hematopoietic stem/progenitor cell population for stem cell transplantation and gene therapy
S Radtke, YY Chan, MA Giese, A Rongvaux, J Adair, HP Kiem
Blood 130, 3339, 2017
12017
Initial Results from Stanford Children’s Fanconi Anemia Clinical Trial Using JSP191 Antibody Conditioning and TCRαβ+ T-Cell/CD19+ B-Cell Depleted Grafts
R Agarwal, A Bertaina, R Nofal, G Saini, N Kunte, S Sen, YY Chan, ...
2023 Tandem Meetings| Transplantation & Cellular Therapy Meetings of ASTCT …, 2023
2023
Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia Mice through Antibody-Mediated Hematopoietic Stem Cell Transplantation
YY Chan, PY Ho, L Swartzrock, M Rayburn, R Nofal, S Thongthip, ...
Blood 140 (Supplement 1), 7342-7344, 2022
2022
Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102
R Nofal, YY Chan, S Sen, U Juarez Figueroa, H Willner, M Felber, ...
Blood 140 (Supplement 1), 7772-7773, 2022
2022
Hematopoiesis post anti-CD117 monoclonal antibody treatment in wild-type and Fanconi anemia settings
M Denis, L Swartzrock, H Willner, QR Bubb, E Haslett, YY Chan, A Chen, ...
Haematologica, 2020
2020
Fully Closed, Large-Scale, and Clinical Grade Cell Sorting of Hematopoietic Stem Cell (HSC)-Enriched CD90+ Cells for Transplantation and Gene Therapy
S Radtke, M Cui, AM Perez, YY Chan, S Schmuck, AJ Berger, T Eunson, ...
Blood 134, 3246, 2019
2019
Fully-Closed System Cell Sorting of CD90 (+) Results in More Efficient Hematopoietic Stem/Progenitor Cell Transduction
S Radtke, M Cui, YY Chan, AM Perez, A Berger, T Eunson, HP Kiem
MOLECULAR THERAPY 27 (4), 85-85, 2019
2019
A Novel Target for Hematopoietic Stem Cell (HSC) Gene Therapy and Editing
S Radtke, M Enstrom, YY Chan, AM Perez, MA Giese, JE Adair, HP Kiem
MOLECULAR THERAPY 26 (5), 16-17, 2018
2018
Early and Stable Engraftment of a Population of Highly-Enriched Long-Term Multi-Potent Hematopoietic Stem Cells
JE Adair, S Radtke, ZK Norgaard, KG Haworth, LE Schefter, MA Giese, ...
MOLECULAR THERAPY 25 (5), 339-339, 2017
2017
Identification and Characterization of a Distinct, Evolutionarily Conserved HSC Phenotype Associated with and Predicting Multi-Lineage Engraftment
S Radtke, MA Giese, YY Chan, ZK Norgaard, JE Adair, HP Kiem
Blood, The Journal of the American Society of Hematology 128 (22), 1153-1153, 2016
2016
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