Frank J Bruggeman
Frank J Bruggeman
Professor, VU University
Verified email at - Homepage
Cited by
Cited by
The nature of systems biology
FJ Bruggeman, HV Westerhoff
TRENDS in Microbiology 15 (1), 45-50, 2007
Cancer: a systems biology disease
JJ Hornberg, FJ Bruggeman, HV Westerhoff, J Lankelma
Biosystems 83 (2-3), 81-90, 2006
Untangling the wires: a strategy to trace functional interactions in signaling and gene networks
BN Kholodenko, A Kiyatkin, FJ Bruggeman, E Sontag, HV Westerhoff, ...
Proceedings of the National Academy of Sciences 99 (20), 12841-12846, 2002
Lost in transition: start-up of glycolysis yields subpopulations of nongrowing cells
JH van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, YJM Bollen, ...
Science 343 (6174), 1245114, 2014
Systems biology: philosophical foundations
F Boogerd, FJ Bruggeman, JHS Hofmeyr, HV Westerhoff
Elsevier, 2007
Control of MAPK signalling: from complexity to what really matters
JJ Hornberg, B Binder, FJ Bruggeman, B Schoeberl, R Heinrich, ...
Oncogene 24 (36), 5533-5542, 2005
Principles behind the multifarious control of signal transduction: ERK phosphorylation and kinase/phosphatase control
JJ Hornberg, FJ Bruggeman, B Binder, CR Geest, AJMB De Vaate, ...
The FEBS journal 272 (1), 244-258, 2005
Emergence and its place in nature: A case study of biochemical networks
FC Boogerd, FJ Bruggeman, RC Richardson, A Stephan, HV Westerhoff
Synthese 145, 131-164, 2005
How fast‐growing bacteria robustly tune their ribosome concentration to approximate growth‐rate maximization
E Bosdriesz, D Molenaar, B Teusink, FJ Bruggeman
The FEBS journal 282 (10), 2029-2044, 2015
Community flux balance analysis for microbial consortia at balanced growth
RA Khandelwal, BG Olivier, WFM Röling, B Teusink, FJ Bruggeman
PloS one 8 (5), e64567, 2013
Effects of sequestration on signal transduction cascades
N Blüthgen, FJ Bruggeman, S Legewie, H Herzel, HV Westerhoff, ...
The FEBS journal 273 (5), 895-906, 2006
Towards building the silicon cell: a modular approach
JL Snoep, F Bruggeman, BG Olivier, HV Westerhoff
Biosystems 83 (2-3), 207-216, 2006
Modular response analysis of cellular regulatory networks
FJ Bruggeman, HV Westerhoff, JB Hoek, BN Kholodenko
Journal of theoretical biology 218 (4), 507-520, 2002
Calcium sensing receptor signalling in physiology and cancer
SC Brennan, U Thiem, S Roth, A Aggarwal, IS Fetahu, S Tennakoon, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (7), 1732-1744, 2013
Elongation dynamics shape bursty transcription and translation
M Dobrzyński, FJ Bruggeman
Proceedings of the National Academy of Sciences 106 (8), 2583-2588, 2009
The volumes and transcript counts of single cells reveal concentration homeostasis and capture biological noise
H Kempe, A Schwabe, F Crémazy, PJ Verschure, FJ Bruggeman
Molecular biology of the cell 26 (4), 797-804, 2015
Systems biology towards life in silico: mathematics of the control of living cells
HV Westerhoff, A Kolodkin, R Conradie, SJ Wilkinson, FJ Bruggeman, ...
Journal of mathematical biology 58, 7-34, 2009
Optimal flux spaces of genome-scale stoichiometric models are determined by a few subnetworks
SM Kelk, BG Olivier, L Stougie, FJ Bruggeman
Scientific reports 2 (1), 1-7, 2012
Systems biology: the elements and principles of life
HV Westerhoff, C Winder, H Messiha, E Simeonidis, M Adamczyk, ...
FEBS letters 583 (24), 3882-3890, 2009
Noise management by molecular networks
FJ Bruggeman, N Blüthgen, HV Westerhoff
PLoS Computational Biology 5 (9), e1000506, 2009
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