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Brian Huntly
Brian Huntly
Unknown affiliation
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ...
Cancer cell 7 (4), 387-397, 2005
35982005
Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ...
New England Journal of Medicine 369 (25), 2391-2405, 2013
19392013
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
E Weisberg, PW Manley, W Breitenstein, J Brüggen, SW Cowan-Jacob, ...
Cancer cell 7 (2), 129-141, 2005
18402005
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
Z Tothova, R Kollipara, BJ Huntly, BH Lee, DH Castrillon, DE Cullen, ...
Cell 128 (2), 325-339, 2007
16712007
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ...
Nature 478 (7370), 529-533, 2011
15642011
Leukaemia stem cells and the evolution of cancer-stem-cell research
BJP Huntly, DG Gilliland
Nature Reviews Cancer 5 (4), 311-321, 2005
8322005
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
BJP Huntly, H Shigematsu, K Deguchi, BH Lee, S Mizuno, N Duclos, ...
Cancer cell 6 (6), 587-596, 2004
8222004
Cancer stem cell definitions and terminology: the devil is in the details
P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ...
Nature Reviews Cancer 12 (11), 767-775, 2012
7402012
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia
K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ...
Cell reports 17 (4), 1193-1205, 2016
5022016
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia
RL Levine, M Loriaux, BJP Huntly, ML Loh, M Beran, E Stoffregen, ...
Blood 106 (10), 3377-3379, 2005
4772005
BET inhibitor resistance emerges from leukaemia stem cells
CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ...
Nature 525 (7570), 538-542, 2015
4522015
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
4382016
Targeting epigenetic readers in cancer
MA Dawson, T Kouzarides, BJP Huntly
New England Journal of Medicine 367 (7), 647-657, 2012
4322012
Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance
D Grimwade, A Ivey, BJP Huntly
Blood, The Journal of the American Society of Hematology 127 (1), 29-41, 2016
4242016
Large deletions at the t (9; 22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia
PB Sinclair, EP Nacheva, M Leversha, N Telford, J Chang, A Reid, ...
Blood, The Journal of the American Society of Hematology 95 (3), 738-743, 2000
3822000
Population dynamics of normal human blood inferred from somatic mutations
H Lee-Six, NF Řbro, MS Shepherd, S Grossmann, K Dawson, M Belmonte, ...
Nature 561 (7724), 473-478, 2018
3792018
Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation
PJ Campbell, EJ Baxter, PA Beer, LM Scott, AJ Bench, BJP Huntly, ...
Blood 108 (10), 3548-3555, 2006
3682006
Reprogramming of T cells to natural killer–like cells upon Bcl11b deletion
P Li, S Burke, J Wang, X Chen, M Ortiz, SC Lee, D Lu, L Campos, ...
Science 329 (5987), 85-89, 2010
3362010
Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia
BJP Huntly, AG Reid, AJ Bench, LJ Campbell, N Telford, P Shepherd, ...
Blood, The Journal of the American Society of Hematology 98 (6), 1732-1738, 2001
2902001
Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1
A Vezzoli, N Bonadies, MD Allen, SMV Freund, CM Santiveri, BT Kvinlaug, ...
Nature structural & molecular biology 17 (5), 617-619, 2010
2332010
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