|Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis|
RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ...
Cancer cell 7 (4), 387-397, 2005
|Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2|
J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ...
New England Journal of Medicine 369 (25), 2391-2405, 2013
|Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl|
E Weisberg, PW Manley, W Breitenstein, J Brüggen, SW Cowan-Jacob, ...
Cancer cell 7 (2), 129-141, 2005
|FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress|
Z Tothova, R Kollipara, BJ Huntly, BH Lee, DH Castrillon, DE Cullen, ...
Cell 128 (2), 325-339, 2007
|Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia|
MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ...
Nature 478 (7370), 529-533, 2011
|Leukaemia stem cells and the evolution of cancer-stem-cell research|
BJP Huntly, DG Gilliland
Nature Reviews Cancer 5 (4), 311-321, 2005
|MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors|
BJP Huntly, H Shigematsu, K Deguchi, BH Lee, S Mizuno, N Duclos, ...
Cancer cell 6 (6), 587-596, 2004
|Cancer stem cell definitions and terminology: the devil is in the details|
P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ...
Nature Reviews Cancer 12 (11), 767-775, 2012
|A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia|
K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ...
Cell reports 17 (4), 1193-1205, 2016
|The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia|
RL Levine, M Loriaux, BJP Huntly, ML Loh, M Beran, E Stoffregen, ...
Blood 106 (10), 3377-3379, 2005
|BET inhibitor resistance emerges from leukaemia stem cells|
CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ...
Nature 525 (7570), 538-542, 2015
|Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition|
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
|Targeting epigenetic readers in cancer|
MA Dawson, T Kouzarides, BJP Huntly
New England Journal of Medicine 367 (7), 647-657, 2012
|Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance|
D Grimwade, A Ivey, BJP Huntly
Blood, The Journal of the American Society of Hematology 127 (1), 29-41, 2016
|Large deletions at the t (9; 22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia|
PB Sinclair, EP Nacheva, M Leversha, N Telford, J Chang, A Reid, ...
Blood, The Journal of the American Society of Hematology 95 (3), 738-743, 2000
|Population dynamics of normal human blood inferred from somatic mutations|
H Lee-Six, NF Řbro, MS Shepherd, S Grossmann, K Dawson, M Belmonte, ...
Nature 561 (7724), 473-478, 2018
|Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation|
PJ Campbell, EJ Baxter, PA Beer, LM Scott, AJ Bench, BJP Huntly, ...
Blood 108 (10), 3548-3555, 2006
|Reprogramming of T cells to natural killer–like cells upon Bcl11b deletion|
P Li, S Burke, J Wang, X Chen, M Ortiz, SC Lee, D Lu, L Campos, ...
Science 329 (5987), 85-89, 2010
|Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia|
BJP Huntly, AG Reid, AJ Bench, LJ Campbell, N Telford, P Shepherd, ...
Blood, The Journal of the American Society of Hematology 98 (6), 1732-1738, 2001
|Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1|
A Vezzoli, N Bonadies, MD Allen, SMV Freund, CM Santiveri, BT Kvinlaug, ...
Nature structural & molecular biology 17 (5), 617-619, 2010