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Artur A. Indzhykulian
Artur A. Indzhykulian
Mass Eye and Ear, Harvard Medical School
Geverifieerd e-mailadres voor hms.harvard.edu - Homepage
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Primary cilia are not calcium-responsive mechanosensors
M Delling, AA Indzhykulian, X Liu, Y Li, T Xie, DP Corey, DE Clapham
Nature 531 (7596), 656-660, 2016
3792016
Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c
B Pan, C Askew, A Galvin, S Heman-Ackah, Y Asai, AA Indzhykulian, ...
Nature biotechnology 35 (3), 264-272, 2017
2792017
Alterations of the CIB2 calcium-and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48
S Riazuddin, IA Belyantseva, APJ Giese, K Lee, AA Indzhykulian, ...
Nature genetics 44 (11), 1265-1271, 2012
2552012
Rescue of hearing by gene delivery to inner-ear hair cells using exosome-associated AAV
B György, C Sage, AA Indzhykulian, DI Scheffer, AR Brisson, S Tan, X Wu, ...
Molecular Therapy 25 (2), 379-391, 2017
1992017
Gene transfer with AAV9-PHP. B rescues hearing in a mouse model of usher syndrome 3A and transduces hair cells in a non-human primate
B György, EJ Meijer, MV Ivanchenko, K Tenneson, F Emond, KS Hanlon, ...
Molecular Therapy-Methods & Clinical Development 13, 1-13, 2019
1362019
Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells
AA Indzhykulian, R Stepanyan, A Nelina, KJ Spinelli, ZM Ahmed, ...
PLoS biology 11 (6), e1001583, 2013
1222013
Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells
AC Velez-Ortega, MJ Freeman, AA Indzhykulian, JM Grossheim, ...
Elife 6, e24661, 2017
872017
Renewed proliferation in adult mouse cochlea and regeneration of hair cells
Y Shu, W Li, M Huang, YZ Quan, D Scheffer, C Tian, Y Tao, X Liu, ...
Nature communications 10 (1), 5530, 2019
822019
TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells
RS Stepanyan, AA Indzhykulian, AC Vélez-Ortega, ET Boger, PS Steyger, ...
Journal of the Association for Research in Otolaryngology 12, 729-740, 2011
812011
The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing
Q Fang, AA Indzhykulian, M Mustapha, GP Riordan, DF Dolan, ...
Elife 4, e08627, 2015
732015
Tryptophan‐rich basic protein (WRB) mediates insertion of the tail‐anchored protein otoferlin and is required for hair cell exocytosis and hearing
C Vogl, I Panou, G Yamanbaeva, C Wichmann, SJ Mangosing, F Vilardi, ...
The EMBO Journal 35 (23), 2536-2552, 2016
652016
XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia
DI Scheffer, DS Zhang, J Shen, A Indzhykulian, KD Karavitaki, YJ Xu, ...
Cell reports 10 (11), 1811-1818, 2015
402015
Hair-cell mechanotransduction persists in TRP channel knockout mice
X Wu, AA Indzhykulian, PD Niksch, RM Webber, M Garcia-Gonzalez, ...
PloS one 11 (5), e0155577, 2016
302016
PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing
X Wu, MV Ivanchenko, H Al Jandal, M Cicconet, AA Indzhykulian, ...
Nature Communications 10 (1), 3801, 2019
282019
Electron microscopy techniques for investigating structure and composition of hair-cell stereociliary bundles
MV Ivanchenko, AA Indzhykulian, DP Corey
Frontiers in Cell and Developmental Biology 9, 744248, 2021
152021
Norrie disease protein is essential for cochlear hair cell maturation
Y Hayashi, H Chiang, CJ Tian, AA Indzhykulian, ASB Edge
Proceedings of the National Academy of Sciences 118 (39), e2106369118, 2021
132021
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F
MV Ivanchenko, DM Hathaway, AJ Klein, B Pan, O Strelkova, ...
Nature Communications 14 (1), 2400, 2023
122023
Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish
M Holmgren, ME Ravicz, KE Hancock, O Strelkova, D Kallogjeri, ...
Elife 10, e69264, 2021
112021
Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell–like cells in adult mice
YZ Quan, W Wei, V Ergin, AP Rameshbabu, M Huang, C Tian, SV Saladi, ...
Proceedings of the National Academy of Sciences 120 (17), e2215253120, 2023
102023
Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F
CW Peters, KS Hanlon, MV Ivanchenko, E Zinn, EF Linarte, Y Li, JM Levy, ...
Molecular Therapy 31 (8), 2439-2453, 2023
72023
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