| The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors I Jordens, M Fernandez-Borja, M Marsman, S Dusseljee, L Janssen, ... Current Biology 11 (21), 1680-1685, 2001 | 918 | 2001 |
| Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning N Rocha, C Kuijl, R Van Der Kant, L Janssen, D Houben, H Janssen, ... Journal of Cell Biology 185 (7), 1209-1225, 2009 | 738 | 2009 |
| Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150Glued, ORP1L, and the receptor βlll spectrin M Johansson, N Rocha, W Zwart, I Jordens, L Janssen, C Kuijl, ... The Journal of cell biology 176 (4), 459-471, 2007 | 570 | 2007 |
| Cross-presentation by intercellular peptide transfer through gap junctions J Neijssen, C Herberts, JW Drijfhout, E Reits, L Janssen, J Neefjes Nature 434 (7029), 83-88, 2005 | 556 | 2005 |
| Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin B Pang, X Qiao, L Janssen, A Velds, T Groothuis, R Kerkhoven, ... Nature communications 4 (1), 1908, 2013 | 432 | 2013 |
| Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1 C Kuijl, NDL Savage, M Marsman, AW Tuin, L Janssen, DA Egan, ... Nature 450 (7170), 725-730, 2007 | 368 | 2007 |
| A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation E Reits, J Neijssen, C Herberts, W Benckhuijsen, L Janssen, JW Drijfhout, ... Immunity 20 (4), 495-506, 2004 | 356 | 2004 |
| Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial–mesenchymal transition GCM Zondag, EE Evers, JP ten Klooster, L Janssen, RA van der Kammen, ... The Journal of cell biology 149 (4), 775-782, 2000 | 355 | 2000 |
| Tamoxifen resistance by a conformational arrest of the estrogen receptor α after PKA activation in breast cancer R Michalides, A Griekspoor, A Balkenende, D Verwoerd, L Janssen, ... Cancer cell 5 (6), 597-605, 2004 | 332 | 2004 |
| An ER-associated pathway defines endosomal architecture for controlled cargo transport MLM Jongsma, I Berlin, RHM Wijdeven, L Janssen, GMC Janssen, ... Cell 166 (1), 152-166, 2016 | 235 | 2016 |
| Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway RH Wijdeven, H Janssen, L Nahidiazar, L Janssen, K Jalink, I Berlin, ... Nature communications 7 (1), 11808, 2016 | 234 | 2016 |
| Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L R van der Kant, A Fish, L Janssen, H Janssen, S Krom, N Ho, ... Journal of cell science 126 (15), 3462-3474, 2013 | 202 | 2013 |
| RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1 M Fernandez-Borja, L Janssen, D Verwoerd, P Hordijk, J Neefjes Journal of cell science 118 (12), 2661-2670, 2005 | 196 | 2005 |
| A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation P Paul, T Van Den Hoorn, MLM Jongsma, MJ Bakker, R Hengeveld, ... Cell 145 (2), 268-283, 2011 | 169 | 2011 |
| Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape W Zwart, A Griekspoor, C Kuijl, M Marsman, J van Rheenen, H Janssen, ... Immunity 22 (2), 221-233, 2005 | 151 | 2005 |
| Characterization of the mammalian CORVET and HOPS complexes and their modular restructuring for endosome specificity R Van Der Kant, CTH Jonker, RH Wijdeven, J Bakker, L Janssen, ... Journal of Biological Chemistry 290 (51), 30280-30290, 2015 | 109 | 2015 |
| Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1 R van der Kant, I Zondervan, L Janssen, J Neefjes Journal of Lipid Research 54 (8), 2153-2165, 2013 | 109 | 2013 |
| Genome-wide identification and characterization of novel factors conferring resistance to topoisomerase II poisons in cancer RH Wijdeven, B Pang, SY van der Zanden, X Qiao, V Blomen, ... Cancer research 75 (19), 4176-4187, 2015 | 106 | 2015 |
| Dynein-mediated Vesicle Transport Controls Intracellular Salmonella Replication M Marsman, I Jordens, C Kuijl, L Janssen, J Neefjes Molecular biology of the cell 15 (6), 2954-2964, 2004 | 98 | 2004 |
| The first step of peptide selection in antigen presentation by MHC class I molecules MA Garstka, A Fish, PHN Celie, RP Joosten, GMC Janssen, I Berlin, ... Proceedings of the National Academy of Sciences 112 (5), 1505-1510, 2015 | 95 | 2015 |
