| E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells J Theys, B Jutten, R Habets, K Paesmans, AJ Groot, P Lambin, ... Radiotherapy and oncology 99 (3), 392-397, 2011 | 265 | 2011 |
| Hypoxia as a target for combined modality treatments BG Wouters, SA Weppler, M Koritzinsky, W Landuyt, S Nuyts, J Theys, ... European Journal of Cancer 38 (2), 240-257, 2002 | 247 | 2002 |
| Drug resistance in non-small cell lung cancer: a potential for NOTCH targeting? V Sosa Iglesias, L Giuranno, LJ Dubois, J Theys, M Vooijs Frontiers in oncology 8, 267, 2018 | 168 | 2018 |
| Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo J Theys, O Pennington, L Dubois, G Anlezark, T Vaughan, A Mengesha, ... British journal of cancer 95 (9), 1212-1219, 2006 | 160 | 2006 |
| Lysine 63-polyubiquitination guards against translesion synthesis–induced mutations RK Chiu, J Brun, C Ramaekers, J Theys, L Weng, P Lambin, DA Gray, ... PLoS genetics 2 (7), e116, 2006 | 158 | 2006 |
| Radio-responsive recA promoter significantly increases TNFα production in recombinant clostridia after 2 Gy irradiation S Nuyts, L Van Mellaert, J Theys, W Landuyt, E Bosmans, J Anné, ... Gene therapy 8 (15), 1197-1201, 2001 | 138 | 2001 |
| Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum J Theys, W Landuyt, S Nuyts, L Van Mellaert, A Van Oosterom, P Lambin, ... Cancer Gene Therapy 8 (4), 294-297, 2001 | 136 | 2001 |
| Colonisation ofClostridiumin the body is restricted to hypoxic and necrotic areas of tumours P Lambin, J Theys, W Landuyt, P Rijken, A Van der Kogel, ... Anaerobe 4 (4), 183-188, 1998 | 114 | 1998 |
| Combining radiotherapy with immunotherapy: the past, the present and the future EJ Van Limbergen, DK De Ruysscher, V Olivo Pimentel, D Marcus, ... The British Journal of Radiology 90 (1076), 20170157, 2017 | 113 | 2017 |
| Development of a flexible and potent hypoxia-inducible promoter for tumor-targeted gene expression in attenuated salmonella A Mengesha, L Dubois, P Lambin, W Landuyt, RK Chiu, BG Wouters, ... Cancer biology & therapy 5 (9), 1120-1128, 2006 | 111 | 2006 |
| Secretory production of biologically active rat interleukin-2 by Clostridium acetobutylicum DSM792 as a tool for anti-tumor treatment S Barbé, L Van Mellaert, J Theys, N Geukens, E Lammertyn, P Lambin, ... FEMS microbiology letters 246 (1), 67-73, 2005 | 108 | 2005 |
| Tumor-specific gene delivery using genetically engineered bacteria J Theys, S Barbé, W Landuyt, S Nuyts, L Mellaert, B Wouters, J Anne, ... Current gene therapy 3 (3), 207-221, 2003 | 103 | 2003 |
| Hypoxia-activated prodrugs and (lack of) clinical progress: The need for hypoxia-based biomarker patient selection in phase III clinical trials L Spiegelberg, R Houben, R Niemans, D de Ruysscher, A Yaromina, ... Clinical and translational radiation oncology 15, 62-69, 2019 | 101 | 2019 |
| Modulation of cell death in the tumor microenvironment BG Wouters, M Koritzinsky, RK Chiu, J Theys, J Buijsen, P Lambin Seminars in radiation oncology 13 (1), 31-41, 2003 | 97 | 2003 |
| In vivo antitumor effect of vascular targeting combined with either ionizing radiation or anti-angiogenesis treatment W Landuyt, B Ahmed, S Nuyts, J Theys, MO de Beeck, A Rijnders, J Anné, ... International Journal of Radiation Oncology* Biology* Physics 49 (2), 443-450, 2001 | 96 | 2001 |
| Clostridium spores for tumor-specific drug delivery S Nuyts, L Van Mellaert, J Theys, W Landuyt, P Lambin, J Anné Anti-cancer drugs 13 (2), 115-125, 2002 | 91 | 2002 |
| NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma S Yahyanejad, H King, VS Iglesias, PV Granton, LMO Barbeau, ... Oncotarget 7 (27), 41251, 2016 | 89 | 2016 |
| Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins AJ Groot, R Habets, S Yahyanejad, CM Hodin, K Reiss, P Saftig, J Theys, ... Molecular and cellular biology 34 (15), 2822-2832, 2014 | 88 | 2014 |
| Radiation-induced bullous pemphigoid: a systematic review of an unusual radiation side effect VEM Mul, AJ van Geest, MCG Pijls-Johannesma, J Theys, ... Radiotherapy and Oncology 82 (1), 5-9, 2007 | 87 | 2007 |
| Stable Escherichia coli-Clostridium acetobutylicum Shuttle Vector for Secretion of Murine Tumor Necrosis Factor Alpha J Theys, S Nuyts, W Landuyt, L Van Mellaert, C Dillen, M Bohringer, ... Applied and environmental microbiology 65 (10), 4295-4300, 1999 | 87 | 1999 |
