Differentiation of induced pluripotent stem cells into functional oligodendrocytes M Czepiel, V Balasubramaniyan, W Schaafsma, M Stancic, H Mikkers, ... Glia 59 (6), 882-892, 2011 | 155 | 2011 |
Towards sustained silencing of HER2/neu in cancer by epigenetic editing F Falahi, C Huisman, HG Kazemier, P van der Vlies, K Kok, GAP Hospers, ... Molecular Cancer Research 11 (9), 1029-1039, 2013 | 99 | 2013 |
Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by artificial transcription factors C Huisman, GBA Wisman, HG Kazemier, MATM van Vugt, ... Molecular oncology 7 (3), 669-679, 2013 | 86 | 2013 |
Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators C Huisman, H Cho, O Brock, SJ Lim, SM Youn, Y Park, S Kim, SK Lee, ... Nature communications 10 (1), 3696, 2019 | 54 | 2019 |
Upregulation of endogenous ICAM‐1 reduces ovarian cancer cell growth in the absence of immune cells ML de Groote, HG Kazemier, C Huisman, BTF van der Gun, MM Faas, ... International Journal of Cancer 134 (2), 280-290, 2014 | 45 | 2014 |
Re-expression of selected epigenetically silenced candidate tumor suppressor genes in cervical cancer by TET2-directed demethylation C Huisman, MGP Van Der Wijst, M Schokker, P Blancafort, MM Terpstra, ... Molecular Therapy 24 (3), 536-547, 2016 | 44 | 2016 |
Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer KG Burfeind, X Zhu, MA Norgard, PR Levasseur, C Huisman, AC Buenafe, ... Elife 9, e54095, 2020 | 41 | 2020 |
Prolonged re-expression of the hypermethylated gene EPB41L3 using artificial transcription factors and epigenetic drugs C Huisman, MGP van der Wijst, F Falahi, J Overkamp, G Karsten, ... Epigenetics 10 (5), 384-396, 2015 | 35 | 2015 |
Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer BTF Van Der Gun, C Huisman, S Stolzenburg, HG Kazemier, MHJ Ruiters, ... British journal of cancer 108 (4), 881-886, 2013 | 34 | 2013 |
Targeting Nrf2 in healthy and malignant ovarian epithelial cells: Protection versus promotion MGP van der Wijst, C Huisman, A Mposhi, G Roelfes, MG Rots Molecular oncology 9 (7), 1259-1273, 2015 | 28 | 2015 |
Chronic cerebral lipocalin 2 exposure elicits hippocampal neuronal dysfunction and cognitive impairment B Olson, X Zhu, MA Norgard, P Diba, PR Levasseur, AC Buenafe, ... Brain, behavior, and immunity 97, 102-118, 2021 | 26 | 2021 |
Microglia in the hypothalamus respond to tumor‐derived factors and are protective against cachexia during pancreatic cancer KG Burfeind, X Zhu, MA Norgard, PR Levasseur, C Huisman, ... Glia 68 (7), 1479-1494, 2020 | 21 | 2020 |
The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus C Huisman, YA Kim, S Jeon, B Shin, J Choi, SJ Lim, SM Youn, Y Park, ... Nature Communications 12 (1), 256, 2021 | 17 | 2021 |
Critical changes in hypothalamic gene networks in response to pancreatic cancer as found by single-cell RNA sequencing C Huisman, MA Norgard, PR Levasseur, SM Krasnow, MGP van der Wijst, ... Molecular metabolism 58, 101441, 2022 | 8 | 2022 |
KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and Is Resilient to TGFβ1 Activation RAF Gjaltema, D Goubert, C Huisman, C Pilar García Tobilla, M Koncz, ... International Journal of Molecular Sciences 21 (10), 3634, 2020 | 7 | 2020 |
Reducing lysil hydroxylase 2 expression in a fibrotic environment by introducing repressive epigenetic marks in the PLOD2 promoter RAF Gjaltema, C Huisman, MG Rots, RA Bank JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 6, 98-98, 2012 | 3 | 2012 |
Bradykinin: a microglia attractant in vivo? C Huisman, P Kok, L Schmaal, P Verhoog Journal of Neuroscience 28 (14), 3531-3532, 2008 | 3 | 2008 |
Re-expression of epigenetically silenced ICAM-1 elucidates its cell-biological role in ovarian cancer cells ML de Groote, HG Kazemier, C Huisman, BTF van der Gun, MM Faas, ... Epigenetic reprogramming of endogenous genes for permanent modulation of …, 2015 | 2 | 2015 |
Gene Regulatory Programs in the Development of Hypothalamic Arcuate Nucleus Neurons JW Lee, C Huisman, S Lee Developmental Neuroendocrinology, 83-103, 2020 | | 2020 |
KRAB-induced heterochromatin is more effective than targeted DNA methylation in achieving efficient and mitotically stable gene repression RAF Gjaltema, C Huisman, CPG Tobilla, PG Jellema, U Brouwer, ... Modifications of collagen and chromatin in ECM-related disease, 191, 2016 | | 2016 |