Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2207 | 2019 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 903 | 2022 |
Frontotemporal dementia and its subtypes: a genome-wide association study R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ... The Lancet Neurology 13 (7), 686-699, 2014 | 381 | 2014 |
Multiple organ involvement by alpha‐synuclein pathology in Lewy body disorders E Gelpi, J Navarro‐Otano, E Tolosa, C Gaig, Y Compta, MJ Rey, MJ Martí, ... Movement Disorders 29 (8), 1010-1018, 2014 | 372 | 2014 |
A phase 2 trial of the GSK‐3 inhibitor tideglusib in progressive supranuclear palsy E Tolosa, I Litvan, GU Höglinger, D Burn, A Lees, MV Andrés, ... Movement Disorders 29 (4), 470-478, 2014 | 316 | 2014 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 288 | 2016 |
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP RJ Guerreiro, M Baquero, R Blesa, M Boada, JM Brás, MJ Bullido, ... Neurobiology of aging 31 (5), 725-731, 2010 | 251 | 2010 |
A longitudinal follow-up of 550 mild cognitive impairment patients: evidence for large conversion to dementia rates and detection of major risk factors involved A Espinosa, M Alegret, S Valero, G Vinyes-Junqué, I Hernández, ... Journal of Alzheimer's Disease 34 (3), 769-780, 2013 | 207 | 2013 |
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 180 | 2021 |
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease V Escott-Price, C Bellenguez, LS Wang, SH Choi, D Harold, L Jones, ... PloS one 9 (6), e94661, 2014 | 147 | 2014 |
Characterization of the repeat expansion size in C9orf72 in amyotrophic lateral sclerosis and frontotemporal dementia O Dols-Icardo, A García-Redondo, R Rojas-García, R Sánchez-Valle, ... Human molecular genetics 23 (3), 749-754, 2014 | 145 | 2014 |
Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19) J Rodríguez-Baño, J Pachón, J Carratala, P Ryan, I Jarrín, M Yllescas, ... Clinical Microbiology and Infection 27 (2), 244-252, 2021 | 137 | 2021 |
Genome‐wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: the GR@ ACE project S Moreno‐Grau, I De Rojas, I Hernández, I Quintela, L Montrreal, ... Alzheimer's & Dementia 15 (10), 1333-1347, 2019 | 136 | 2019 |
Assessing the role of the TREM2 p. R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia A Ruiz, O Dols-Icardo, MJ Bullido, P Pastor, E Rodríguez-Rodríguez, ... Neurobiology of aging 35 (2), 444. e1-444. e4, 2014 | 131 | 2014 |
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases R Ferrari, Y Wang, J Vandrovcova, S Guelfi, A Witeolar, CM Karch, ... Journal of Neurology, Neurosurgery & Psychiatry 88 (2), 152-164, 2017 | 125 | 2017 |
Amyloid-targeted therapeutics in Alzheimer's disease: use of human albumin in plasma exchange as a novel approach for Abeta mobilization. M Boada, P Ortiz, F Anaya, I Hernández, J Muñoz, L Núñez, J Olazarán, ... Drug news & perspectives 22 (6), 325-339, 2009 | 122 | 2009 |
Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration J Van Der Zee, T Van Langenhove, GG Kovacs, L Dillen, W Deschamps, ... Acta neuropathologica 128, 397-410, 2014 | 119 | 2014 |
The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease C Antúnez, M Boada, A González-Pérez, J Gayán, R Ramírez-Lorca, ... Genome medicine 3, 1-8, 2011 | 117 | 2011 |
Investigation of c9orf72 in 4 neurodegenerative disorders Z Xi, L Zinman, Y Grinberg, D Moreno, C Sato, JM Bilbao, M Ghani, ... Archives of neurology 69 (12), 1583-1590, 2012 | 113 | 2012 |
Follow-up of loci from the International Genomics of Alzheimer’s Disease Project identifies TRIP4 as a novel susceptibility gene A Ruiz, S Heilmann, T Becker, I Hernández, H Wagner, M Thelen, ... Translational psychiatry 4 (2), e358-e358, 2014 | 111 | 2014 |