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| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum SJ Marciniak, CY Yun, S Oyadomari, I Novoa, Y Zhang, R Jungreis, ... Genes & development 18 (24), 3066-3077, 2004 | 1774 | 2004 |
| Endoplasmic reticulum stress signaling in disease SJ Marciniak, D Ron Physiological reviews 86 (4), 1133-1149, 2006 | 1003 | 2006 |
| Targeted gene correction of α 1-antitrypsin deficiency in induced pluripotent stem cells K Yusa, ST Rashid, H Strick-Marchand, I Varela, PQ Liu, DE Paschon, ... Nature 478 (7369), 391-394, 2011 | 703 | 2011 |
| Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells ST Rashid, S Corbineau, N Hannan, SJ Marciniak, E Miranda, ... The Journal of clinical investigation 120 (9), 3127-3136, 2010 | 623 | 2010 |
| Paneth cells as a site of origin for intestinal inflammation TE Adolph, MF Tomczak, L Niederreiter, HJ Ko, J Böck, E Martinez-Naves, ... Nature 503 (7475), 272-276, 2013 | 546 | 2013 |
| Cytoprotection by pre‐emptive conditional phosphorylation of translation initiation factor 2 PD Lu, C Jousse, SJ Marciniak, Y Zhang, I Novoa, D Scheuner, ... The EMBO journal 23 (1), 169-179, 2004 | 391 | 2004 |
| Endoplasmic reticulum dysfunction in neurological disease BD Roussel, AJ Kruppa, E Miranda, DC Crowther, DA Lomas, ... The Lancet Neurology 12 (1), 105-118, 2013 | 388 | 2013 |
| Endoplasmic reticulum stress in malignancy HJ Clarke, JE Chambers, E Liniker, SJ Marciniak Cancer cell 25 (5), 563-573, 2014 | 330 | 2014 |
| The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ... Nature 510 (7504), 268-272, 2014 | 265 | 2014 |
| Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation L Long, X Yang, M Southwood, J Lu, SJ Marciniak, BJ Dunmore, ... Circulation research 112 (8), 1159-1170, 2013 | 213 | 2013 |
| Iron promotes the toxicity of amyloid β peptide by impeding its ordered aggregation B Liu, A Moloney, S Meehan, K Morris, SE Thomas, LC Serpell, R Hider, ... Journal of Biological Chemistry 286 (6), 4248-4256, 2011 | 186 | 2011 |
| Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK SJ Marciniak, L Garcia-Bonilla, J Hu, HP Harding, D Ron The Journal of cell biology 172 (2), 201-209, 2006 | 149 | 2006 |
| A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1‐antitrypsin deficiency E Miranda, J Pérez, UI Ekeowa, N Hadzic, N Kalsheker, B Gooptu, ... Hepatology 52 (3), 1078-1088, 2010 | 127 | 2010 |
| Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins H Kroeger, E Miranda, I MacLeod, J Pérez, DC Crowther, SJ Marciniak, ... Journal of Biological Chemistry 284 (34), 22793-22802, 2009 | 123 | 2009 |
| Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease EL Thomas, AE Brynes, G Hamilton, N Patel, A Spong, RD Goldin, G Frost, ... World journal of gastroenterology: WJG 12 (36), 5813, 2006 | 123 | 2006 |
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| Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1‐antitrypsin deficiency A Ordóñez, EL Snapp, L Tan, E Miranda, SJ Marciniak, DA Lomas Hepatology 57 (5), 2049-2060, 2013 | 100 | 2013 |
| Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression HP Harding, Y Zhang, S Khersonsky, S Marciniak, D Scheuner, ... Cell metabolism 2 (6), 361-371, 2005 | 87 | 2005 |
| Neuroserpin polymers activate NF-κB by a calcium signaling pathway that is independent of the unfolded protein response MJ Davies, E Miranda, BD Roussel, RJ Kaufman, SJ Marciniak, ... Journal of Biological Chemistry 284 (27), 18202-18209, 2009 | 78 | 2009 |
Joseph Edward ChambersUniversity of CambridgeVerified email at cam.ac.uk
