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Thomas H Sharp
Thomas H Sharp
Associate Professor at Leiden University Medical Center
Verified email at lumc.nl - Homepage
Title
Cited by
Cited by
Year
Self-assembling cages from coiled-coil peptide modules
JM Fletcher, RL Harniman, FRH Barnes, AL Boyle, A Collins, J Mantell, ...
Science 340 (6132), 595-599, 2013
4582013
Modular design of self-assembling peptide-based nanotubes
NC Burgess, TH Sharp, F Thomas, CW Wood, AR Thomson, NR Zaccai, ...
Journal of the American Chemical Society 137 (33), 10554-10562, 2015
1392015
Mucosal reactive oxygen species decrease virulence by disrupting Campylobacter jejuni phosphotyrosine signaling
N Corcionivoschi, LAJ Alvarez, TH Sharp, M Strengert, A Alemka, ...
Cell host & microbe 12 (1), 47-59, 2012
1102012
Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement
D Ugurlar, SC Howes, BJ de Kreuk, RI Koning, RN de Jong, FJ Beurskens, ...
Science 359 (6377), 794-797, 2018
1082018
Squaring the Circle in Peptide Assembly: From Fibers to Discrete Nanostructures by de Novo Design
AL Boyle, EHC Bromley, GJ Bartlett, RB Sessions, TH Sharp, CL Williams, ...
Journal of the american chemical society 134 (37), 15457-15467, 2012
1002012
Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses
X Xue, J Wu, D Ricklin, F Forneris, P Di Crescenzio, CQ Schmidt, ...
Nature structural & molecular biology 24 (8), 643-651, 2017
782017
Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b
TH Sharp, AL Boyle, CA Diebolder, A Kros, AJ Koster, P Gros
Proceedings of the National Academy of Sciences 116 (24), 11900-11905, 2019
762019
Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins
MW Tuijtel, AJ Koster, S Jakobs, FGA Faas, TH Sharp
Scientific Reports 9 (1), 1-11, 2019
762019
Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design
TH Sharp, M Bruning, J Mantell, RB Sessions, AR Thomson, NR Zaccai, ...
Proceedings of the National Academy of Sciences 109 (33), 13266-13271, 2012
762012
Advances in cryo-electron tomography for biology and medicine
RI Koning, AJ Koster, TH Sharp
Annals of Anatomy-Anatomischer Anzeiger 217, 82-96, 2018
712018
Heterogeneous MAC initiator and pore structures in a lipid bilayer by phase-plate cryo-electron tomography
TH Sharp, AJ Koster, P Gros
Cell reports 15 (1), 1-8, 2016
652016
Intracellular membrane traffic at high resolution
JRT van Weering, E Brown, TH Sharp, J Mantell, PJ Cullen, P Verkade
Methods in cell biology 96, 619-648, 2010
492010
Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability
A Easter, TH Sharp, JP Valentin, CE Pollard
Journal of pharmacological and toxicological methods 56 (2), 223-233, 2007
492007
An engineered dimeric protein pore that spans adjacent lipid bilayers
S Mantri, K Tanuj Sapra, S Cheley, TH Sharp, H Bayley
Nature communications 4 (1), 1-10, 2013
462013
Targeted anion transporter delivery by coiled-coil driven membrane fusion
NL Mora, A Bahreman, H Valkenier, H Li, TH Sharp, DN Sheppard, ...
Chemical science 7 (3), 1768-1772, 2016
422016
Squaramide-based supramolecular materials for three-dimensional cell culture of human induced pluripotent stem cells and their derivatives
C Tong, T Liu, V Saez Talens, WEM Noteborn, TH Sharp, MMRM Hendrix, ...
Biomacromolecules 19 (4), 1091-1099, 2018
272018
Capturing Endocytic Segregation Events with HPF-CLEM
E Brown, J van Weering, T Sharp, J Mantell, P Verkade
Correlative Light and Electron MIcroscopy, 175, 2012
192012
Olfactomedin-1 has a V-shaped disulfide-linked tetrameric structure
MF Pronker, TGAA Bos, TH Sharp, DME Thies-Weesie, BJC Janssen
Journal of Biological Chemistry 290 (24), 15092-15101, 2015
152015
Imaging complement by phase-plate cryo-electron tomography from initiation to pore formation
TH Sharp, FGA Faas, AJ Koster, P Gros
Journal of Structural Biology 197 (2), 155-162, 2017
132017
Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision
MW Tuijtel, AA Mulder, CC Posthuma, B van der Hoeven, AJ Koster, ...
Scientific reports 7 (1), 1-12, 2017
122017
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