|Clinical update on head and neck cancer: molecular biology and ongoing challenges|
TSMT Elham Alsahafi, Katheryn Begg, Ivano Amelio, Nina Raulf, Philippe Lucarelli
Cell Death & Diseasevolume 10 (540 (2019)), 2019
|Downregulation of the TGFβ Pseudoreceptor BAMBI in Non–Small Cell Lung Cancer Enhances TGFβ Signaling and InvasionRole of BAMBI in Lung Cancer|
S Marwitz, S Depner, D Dvornikov, R Merkle, M Szczygieł, ...
Cancer research 76 (13), 3785-3801, 2016
|Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers|
N Raulf, P Lucarelli, S Thavaraj, S Brown, JM Vicencio, T Sauter, ...
European Journal of Cancer 102, 52-68, 2018
|Dynamics and feedback loops in the transforming growth factor β signaling pathway|
K Wegner, A Bachmann, JU Schad, P Lucarelli, S Sahle, P Nickel, ...
Biophysical chemistry 162, 22-34, 2012
|Resolving the combinatorial complexity of smad protein complex formation and its link to gene expression|
P Lucarelli, M Schilling, C Kreutz, A Vlasov, ME Boehm, N Iwamoto, ...
Cell systems 6 (1), 75-89. e11, 2018
|Cancer cells employ nuclear caspase-8 to overcome the p53-dependent G2/M checkpoint through cleavage of USP28|
I Müller, E Strozyk, S Schindler, S Beissert, HZ Oo, T Sauter, P Lucarelli, ...
Molecular cell 77 (5), 970-984. e7, 2020
|Context-specific flow through the MEK/ERK module produces cell-and ligand-specific patterns of ERK single and double phosphorylation|
N Iwamoto, LA D’Alessandro, S Depner, B Hahn, BA Kramer, P Lucarelli, ...
Science signaling 9 (413), ra13-ra13, 2016
|Machine learning-assisted neurotoxicity prediction in human midbrain organoids|
AS Monzel, K Hemmer, T Kaoma, LM Smits, S Bolognin, P Lucarelli, ...
Parkinsonism & Related Disorders 75, 105-109, 2020
|Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients|
SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ...
Parkinsonism & Related Disorders 67, 48-55, 2019
|Model based targeting of IL-6-induced inflammatory responses in cultured primary hepatocytes to improve application of the JAK inhibitor ruxolitinib|
S Sobotta, A Raue, X Huang, J Vanlier, A Jünger, S Bohl, U Albrecht, ...
Frontiers in physiology 8, 775, 2017
|FALCON: a toolbox for the fast contextualization of logical networks|
S De Landtsheer, P Trairatphisan, P Lucarelli, T Sauter
Bioinformatics 33 (21), 3431-3436, 2017
|Hypoxia routes tryptophan homeostasis towards increased tryptamine production|
SR Mohapatra, A Sadik, S Sharma, G Poschet, HM Gegner, TV Lanz, ...
Frontiers in immunology 12, 590532, 2021
|Stroma-induced phenotypic plasticity offers phenotype-specific targeting to improve melanoma treatment|
K Seip, K Jřrgensen, MV Haselager, M Albrecht, MH Haugen, ...
Cancer letters 439, 1-13, 2018
|Clinical update on head and neck cancer: molecular biology and ongoing challenges. Cell Death Dis. 2019; 10 (8): 540|
E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli, T Sauter, M Tavassoli
|ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1|
Ž Frangež, D Gérard, Z He, M Gavriil, Y Fernández-Marrero, ...
Frontiers in oncology, 3152, 2021
|Excemplify: a flexible template based solution, parsing and managing data in spreadsheets for experimentalists|
L Shi, L Jong, U Wittig, P Lucarelli, M Stepath, S Mueller, LA D‘Alessandro, ...
Journal of integrative bioinformatics 10 (2), 58-70, 2013
|Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma|
G Del Mistro, P Lucarelli, I Mueller, S De Landtsheer, A Zinoveva, M Hutt, ...
NPJ systems biology and applications 4 (1), 1-12, 2018
|Using regularization to infer cell line specificity in logical network models of signaling pathways|
S De Landtsheer, P Lucarelli, T Sauter
Frontiers in physiology 9, 550, 2018
|L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness|
RAC Machado, D Stojevski, S De Landtsheer, P Lucarelli, A Baron, ...
Cell Communication and Signaling 19 (1), 1-22, 2021
|Computational models of melanoma|
M Albrecht, P Lucarelli, D Kulms, T Sauter
Theoretical Biology and Medical Modelling 17 (1), 1-16, 2020