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Michiel van Gent
Michiel van Gent
Postdoc, Erasmus Medical Center Rotterdam
Geverifieerd e-mailadres voor erasmusmc.nl
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TRIM proteins and their roles in antiviral host defenses
M van Gent, KMJ Sparrer, MU Gack
Annual review of virology 5, 385-405, 2018
2532018
ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity
GQ Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ...
Nature microbiology 6 (4), 467-478, 2021
2102021
Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity
JJ Chiang, KMJ Sparrer, M van Gent, C Lässig, T Huang, N Osterrieder, ...
Nature immunology 19 (1), 53-62, 2018
2102018
Topology and membrane anchoring of the coronavirus replication complex: not all hydrophobic domains of nsp3 and nsp6 are membrane spanning
M Oostra, MC Hagemeijer, M van Gent, CPJ Bekker, EG te Lintelo, ...
Journal of virology 82 (24), 12392-12405, 2008
1932008
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling
M van Gent, SGE Braem, A de Jong, N Delagic, JGC Peeters, IGJ Boer, ...
PLoS pathogens 10 (2), e1003960, 2014
1602014
Immune evasion by Epstein-Barr virus
ME Ressing, M van Gent, AM Gram, MJG Hooykaas, SJ Piersma, ...
Epstein Barr Virus Volume 2: One Herpes Virus: Many Diseases, 355-381, 2015
1522015
EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection
M van Gent, BD Griffin, EG Berkhoff, D van Leeuwen, IGJ Boer, M Buisson, ...
The Journal of Immunology 186 (3), 1694-1702, 2011
1132011
EBV microrna BART16 suppresses type I ifn signaling
MJG Hooykaas, M Van Gent, JA Soppe, E Kruse, IGJ Boer, D Van Leenen, ...
The Journal of Immunology 198 (10), 4062-4073, 2017
932017
Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin
AT Tromp, M Van Gent, P Abrial, A Martin, JP Jansen, CJC De Haas, ...
Nature microbiology 3 (6), 708-717, 2018
872018
A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase
KD Buchan, TK Prajsnar, NV Ogryzko, NWM De Jong, M Van Gent, ...
PLoS One 14 (4), e0215592, 2019
542019
Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity
F Full, M van Gent, KMJ Sparrer, C Chiang, MA Zurenski, M Scherer, ...
Nature microbiology 4 (1), 164-176, 2019
422019
Silencing the shutoff protein of Epstein–Barr virus in productively infected B cells points to (innate) targets for immune evasion
M Van Gent, AM Gram, IGJ Boer, RJ Geerdink, MFS Lindenbergh, ...
Journal of General Virology 96 (4), 858-865, 2015
362015
High-throughput RNA sequencing of paraformaldehyde-fixed single cells
HV Phan, M van Gent, N Drayman, A Basu, MU Gack, S Tay
Nature Communications 12 (1), 5636, 2021
302021
ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease
GQ Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ...
Biorxiv, 2020
192020
ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity. Nat Microbiol 6: 467–478
G Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ...
172021
The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I
X Liu, Y Ma, K Voss, M van Gent, YK Chan, MU Gack, M Gale Jr, B He
PLoS pathogens 17 (3), e1009446, 2021
162021
Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV
M van Gent, A Reich, SE Velu, MU Gack
PLoS Biology 19 (2), e3001097, 2021
122021
The US3 kinase of herpes simplex virus phosphorylates the RNA sensor RIG-I to suppress innate immunity
M van Gent, JJ Chiang, S Muppala, C Chiang, W Azab, L Kattenhorn, ...
Journal of Virology 96 (4), e01510-21, 2022
102022
GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141
L Naesens, S Muppala, D Acharya, J Nemegeer, D Bogaert, JH Lee, ...
Science immunology 7 (77), eabq4531, 2022
82022
Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity
AT Tromp, M Van Gent, JP Jansen, LM Scheepmaker, A Velthuizen, ...
Toxins 12 (2), 106, 2020
82020
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