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Shayne D. Wierbowski
Shayne D. Wierbowski
Ph.D Candidate in Computational Biology, Cornell University
Verified email at cornell.edu - Homepage
Title
Cited by
Cited by
Year
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao, Y Luo, J Judd, ...
Nature biotechnology 41 (1), 128-139, 2023
842023
Transcription imparts architecture, function and logic to enhancer units
ND Tippens, J Liang, AKY Leung, SD Wierbowski, A Ozer, JG Booth, ...
Nature genetics 52 (10), 1067-1075, 2020
632020
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
R Pourhaghighi, PEA Ash, S Phanse, F Goebels, LZM Hu, S Chen, ...
Cell systems 10 (4), 333-350. e14, 2020
582020
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
R Fragoza, J Das, SD Wierbowski, J Liang, TN Tran, S Liang, JF Beltran, ...
Nature communications 10 (1), 4141, 2019
562019
Genetics of extreme human longevity to guide drug discovery for healthy ageing
ZD Zhang, S Milman, JR Lin, S Wierbowski, H Yu, N Barzilai, ...
Nature metabolism 2 (8), 663-672, 2020
462020
Cross‐docking benchmark for automated pose and ranking prediction of ligand binding
SD Wierbowski, BM Wingert, J Zheng, CJ Camacho
Protein Science 29 (1), 298-305, 2020
402020
Structure-based validation can drastically underestimate error rate in proteome-wide cross-linking mass spectrometry studies
K Yugandhar, TY Wang, SD Wierbowski, EE Shayhidin, H Yu
Nature methods 17 (10), 985-988, 2020
302020
A 3D structural SARS-CoV-2–human interactome to explore genetic and drug perturbations
SD Wierbowski, S Liang, Y Liu, Y Chen, S Gupta, NM Andre, SM Lipkin, ...
Nature methods 18 (12), 1477-1488, 2021
232021
Deep learning methods for 3D structural proteome and interactome modeling
D Lee, D Xiong, S Wierbowski, L Li, S Liang, H Yu
Current opinion in structural biology 73, 102329, 2022
192022
A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice
SD Wierbowski, TV Vo, P Falter-Braun, TO Jobe, LH Kruse, X Wei, J Liang, ...
Proceedings of the National Academy of Sciences 117 (21), 11836-11842, 2020
162020
Extracting complementary insights from molecular phenotypes for prioritization of disease-associated mutations
SD Wierbowski, R Fragoza, S Liang, H Yu
Current opinion in systems biology 11, 107-116, 2018
52018
A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19
Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao, Y Luo, J Judd, ...
Research Square, 2022
42022
A full-proteome, interaction-specific characterization of mutational hotspots across human cancers
S Chen, Y Liu, Y Zhang, SD Wierbowski, SM Lipkin, X Wei, H Yu
Genome Research 32 (1), 135-149, 2022
32022
A 3D structural interactome to explore the impact of evolutionary divergence, population variation, and small-molecule drugs on SARS-CoV-2-human protein-protein interactions
SD Wierbowski, S Liang, Y Chen, NM Andre, SM Lipkin, GR Whittaker, ...
bioRxiv, 2020.10. 13.308676, 2020
32020
Macromolecular Connectivity Landscape of Mammalian Brain
R Pourhaghighi, PEA Ash, S Phanse, F Goebels, E Malolepsza, K Tsafou, ...
12018
A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology
Y Zhang, AK Leung, T Qiu, L Li, J Zhang, S Wierbowski, J Booth, H Yu
bioRxiv, 2023.03. 06.531441, 2023
2023
DeepERA: deep learning enables comprehensive identification of drug-target interactions via embedding of heterogeneous data
L Li, SD Wierbowski, H Yu
bioRxiv, 2023.01. 27.525827, 2023
2023
Protein Interaction Network Based Approaches to Characterize Protein Function, Molecularly Profile Genetic Variants, and Investigate Mechanisms Linked to Viral-host Pathology …
SD Wierbowski
Cornell University, 2022
2022
Combining views for newly sequenced organisms
Y Zhang, SD Wierbowski, H Yu
Nature Machine Intelligence 3 (12), 1011-1012, 2021
2021
Considerations in Molecular Docking: Presenting DISCO, a DIrectory of Structures for CrossdOcking, as a Novel Docking Benchmark and Applying it to Refine the Molecular Docking …
SD Wierbowski
University of Scranton, 2016
2016
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