| Inflammation and Alzheimer’s disease H Akiyama, S Barger, S Barnum, B Bradt, J Bauer, GM Cole, NR Cooper, ... Neurobiology of aging 21 (3), 383-421, 2000 | 5619 | 2000 |
| Neuroinflammation in Alzheimer's disease MT Heneka, MJ Carson, J El Khoury, GE Landreth, F Brosseron, ... The Lancet Neurology 14 (4), 388-405, 2015 | 5286 | 2015 |
| ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models PE Cramer, JR Cirrito, DW Wesson, CYD Lee, JC Karlo, AE Zinn, ... science 335 (6075), 1503-1506, 2012 | 1234 | 2012 |
| ApoE promotes the proteolytic degradation of Aβ Q Jiang, CYD Lee, S Mandrekar, B Wilkinson, P Cramer, N Zelcer, ... Neuron 58 (5), 681-693, 2008 | 1108 | 2008 |
| β-Amyloid stimulation of microglia and monocytes results in TNFα-dependent expression of inducible nitric oxide synthase and neuronal apoptosis CK Combs, JC Karlo, SC Kao, GE Landreth Journal of Neuroscience 21 (4), 1179-1188, 2001 | 915 | 2001 |
| Inflammatory mechanisms in Alzheimer's disease: inhibition of β-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARγ agonists CK Combs, DE Johnson, JC Karlo, SB Cannady, GE Landreth Journal of Neuroscience 20 (2), 558-567, 2000 | 807 | 2000 |
| Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitroanalysis of inflammation-induced secondary injury after CNS trauma MT Fitch, C Doller, CK Combs, GE Landreth, J Silver Journal of neuroscience 19 (19), 8182-8198, 1999 | 785 | 1999 |
| The role of microglia in amyloid clearance from the AD brain CYD Lee, GE Landreth Journal of neural transmission 117, 949-960, 2010 | 727 | 2010 |
| A cell surface receptor complex for fibrillar β-amyloid mediates microglial activation ME Bamberger, ME Harris, DR McDonald, J Husemann, GE Landreth Journal of Neuroscience 23 (7), 2665-2674, 2003 | 726 | 2003 |
| Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1–42 levels in APPV717I transgenic mice MT Heneka, M Sastre, L Dumitrescu-Ozimek, A Hanke, I Dewachter, ... Brain 128 (6), 1442-1453, 2005 | 719 | 2005 |
| TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models TR Jay, CM Miller, PJ Cheng, LC Graham, S Bemiller, ML Broihier, G Xu, ... Journal of Experimental Medicine 212 (3), 287-295, 2015 | 691 | 2015 |
| Anti-inflammatory drug therapy alters β-amyloid processing and deposition in an animal model of Alzheimer's disease Q Yan, J Zhang, H Liu, S Babu-Khan, R Vassar, AL Biere, M Citron, ... Journal of Neuroscience 23 (20), 7504-7509, 2003 | 658 | 2003 |
| CD14 and toll-like receptors 2 and 4 are required for fibrillar Aβ-stimulated microglial activation EG Reed-Geaghan, JC Savage, AG Hise, GE Landreth Journal of Neuroscience 29 (38), 11982-11992, 2009 | 628 | 2009 |
| A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells S Dillon, A Agrawal, T Van Dyke, G Landreth, L McCauley, A Koh, ... The Journal of Immunology 172 (8), 4733-4743, 2004 | 602 | 2004 |
| Inflammation, microglia, and Alzheimer's disease B Cameron, GE Landreth Neurobiology of disease 37 (3), 503-509, 2010 | 599 | 2010 |
| Antineoplastic effects of peroxisome proliferatoractivated receptor γ agonists C Grommes, GE Landreth, MT Heneka The lancet oncology 5 (7), 419-429, 2004 | 583 | 2004 |
| Microglial phagocytosis induced by fibrillar β-amyloid and IgGs are differentially regulated by proinflammatory cytokines J Koenigsknecht-Talboo, GE Landreth Journal of Neuroscience 25 (36), 8240-8249, 2005 | 578 | 2005 |
| Microglia and inflammation in Alzheimer's disease S Mandrekar-Colucci, GE Landreth CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010 | 523 | 2010 |
| Microglial phagocytosis of fibrillar β-amyloid through a β1 integrin-dependent mechanism J Koenigsknecht, G Landreth Journal of Neuroscience 24 (44), 9838-9846, 2004 | 520 | 2004 |
| Protective action of the peroxisome proliferator‐activated receptor‐γ agonist pioglitazone in a mouse model of Parkinson's disease T Breidert, J Callebert, MT Heneka, G Landreth, JM Launay, EC Hirsch Journal of neurochemistry 82 (3), 615-624, 2002 | 491 | 2002 |
