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Failure of human rhombic lip differentiation underlies medulloblastoma formation LD Hendrikse, P Haldipur, O Saulnier, J Millman, AH Sjoboen, ... Nature 609 (7929), 1021-1028, 2022 | 71 | 2022 |
TCF12 is mutated in anaplastic oligodendroglioma K Labreche, I Simeonova, A Kamoun, V Gleize, D Chubb, E Letouzé, ... Nature communications 6, 2015 | 50 | 2015 |
ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin I Tanaka, A Chakraborty, O Saulnier, C Benoit-Pilven, S Vacher, D Labiod, ... Nucleic acids research 48 (5), 2676-2693, 2020 | 34 | 2020 |
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate J Zagozewski, GM Shahriary, LC Morrison, O Saulnier, M Stromecki, ... Nature Communications 11 (1), 3627, 2020 | 25 | 2020 |
Targeting microglial metabolic rewiring synergizes with immune-checkpoint blockade therapy for glioblastoma Z Ye, X Ai, K Yang, Z Yang, F Fei, X Liao, Z Qiu, RC Gimple, H Yuan, ... Cancer discovery 13 (4), 974-1001, 2023 | 16 | 2023 |
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions J Vibert, O Saulnier, C Collin, F Petit, KJE Borgman, J Vigneau, M Gautier, ... Molecular Cell 82 (13), 2458-2471. e9, 2022 | 16 | 2022 |
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion O Saulnier, K Guedri-Idjouadiene, MM Aynaud, A Chakraborty, J Bruyr, ... Nucleic Acids Research 49 (9), 5038-5056, 2021 | 13 | 2021 |
A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis H Zou, B Poore, EE Brown, J Qian, B Xie, E Asimakidou, V Razskazovskiy, ... Nature cell biology 25 (3), 493-507, 2023 | 9 | 2023 |
Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression J Zagozewski, S Borlase, BJ Guppy, L Coudière-Morrison, GM Shahriary, ... Communications Biology 5 (1), 697, 2022 | 9 | 2022 |
The LIN28B–let‐7–PBK pathway is essential for group 3 medulloblastoma tumor growth and survival SW Shahab, CM Roggeveen, J Sun, H Kunhiraman, LF McSwain, ... Molecular Oncology 17 (9), 1784-1802, 2023 | 5 | 2023 |
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism L Zhao, Z Qiu, Z Yang, L Xu, TM Pearce, Q Wu, K Yang, FL Li, O Saulnier, ... Nature Cancer, 1-20, 2024 | 4 | 2024 |
Abstract NG06: Tracing the developmental origins of group 3 medulloblastoma O Saulnier Cancer Research 84 (7_Supplement), NG06-NG06, 2024 | | 2024 |
A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and MYC that promotes group 3 medulloblastoma K Katsushima, K Joshi, M Yuan, B Romero, M Batish, S Stapleton, G Jallo, ... Cell Reports 43 (3), 2024 | | 2024 |
miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4 M Yuan, I Mahmud, K Katsushima, K Joshi, O Saulnier, R Pokhrel, B Lee, ... Acta Neuropathologica Communications 11 (1), 203, 2023 | | 2023 |
Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma V Daggubati, A Vykunta, A Choudhury, Z Qadeer, K Mirchia, O Saulnier, ... Research Square, 2023 | | 2023 |
MDB-21. THE OTX2-REGULATED ALTERNATIVE SPLICING LANDSCAPE CONTROLS DIFFERENTIATION AND RECONSTITUTES THE DEVELOPMENTAL ORIGINS OF GROUP 3 MEDULLOBLASTOMA O Saulnier, J Zagozewski, L Liang, LD Hendrikse, V Gordon, KA Aldinger, ... Neuro-Oncology 25 (Suppl 1), i66, 2023 | | 2023 |