| Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling M Frega, K Linda, JM Keller, G Gümüş-Akay, B Mossink, JR van Rhijn, ... Nature communications 10 (1), 4928, 2019 | 125 | 2019 |
| Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro B Mossink, AHA Verboven, EJH van Hugte, TMK Gunnewiek, G Parodi, ... Stem cell reports 16 (9), 2182-2196, 2021 | 72 | 2021 |
| m. 3243A> G-induced mitochondrial dysfunction impairs human neuronal development and reduces neuronal network activity and synchronicity TMK Gunnewiek, EJH Van Hugte, M Frega, GS Guardia, K Foreman, ... Cell reports 31 (3), 2020 | 70* | 2020 |
| Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks B Mossink, JR Van Rhijn, S Wang, K Linda, MR Vitale, JEM Zöller, ... Molecular Psychiatry 27 (1), 1-18, 2022 | 61 | 2022 |
| Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders K Linda, EI Lewerissa, AHA Verboven, M Gabriele, M Frega, ... Autophagy 18 (2), 423-442, 2022 | 54 | 2022 |
| MicroRNA-338 attenuates cortical neuronal outgrowth by modulating the expression of axon guidance genes A Kos, T Klein-Gunnewiek, J Meinhardt, NFMO Loohuis, H van Bokhoven, ... Molecular neurobiology 54, 3439-3452, 2017 | 27 | 2017 |
| Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips HHT Middelkamp, AHA Verboven, AG De Sá Vivas, C Schoenmaker, ... Scientific reports 11 (1), 2281, 2021 | 20 | 2021 |
| Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m. 3243A> G heteroplasmy in iPSC-derived neurons TMK Gunnewiek, AHA Verboven, I Pelgrim, M Hogeweg, C Schoenmaker, ... Stem Cell Reports 16 (9), 2197-2212, 2021 | 11 | 2021 |
| Modulation of glucocorticoids by the serotonin transporter polymorphism: A narrative review TMK Gunnewiek, JR Homberg, T Kozicz Neuroscience & Biobehavioral Reviews 92, 338-349, 2018 | 10 | 2018 |
| Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons JR Van Rhijn, Y Shi, M Bormann, B Mossink, M Frega, H Recaioglu, ... Neurobiology of disease 163, 105587, 2022 | 9 | 2022 |
| Neuronal network dysfunction in a human model for Kleefstra syndrome mediated by enhanced NMDAR signaling M Frega, K Linda, JM Keller, G Gümüş-Akay, B Mossink, JR van Rhijn, ... bioRxiv, 585596, 2019 | 7 | 2019 |
| Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling. Nat. Commun. 10, 1–15 M Frega, K Linda, JM Keller, G Gümüsç-Akay, B Mossink, JR van Rhijn, ... | 6 | 2019 |
| KANSL1 deficiency causes neuronal dysfunction by oxidative stress-induced autophagy K Linda, EII Lewerissa, AHA Verboven, M Gabriele, M Frega, ... bioRxiv, 2020.08. 07.241257, 2020 | 3 | 2020 |
| Brain-on-a-chip-a neurophysiological model of MELAS disease and comorbid psychopathology T Kozicz, T Klein-Gunnewiek, D Cassiman, T Nelson, R Rodenburg, ... European Journal Of Human Genetics 27, 1161-1162, 2019 | 1 | 2019 |
| Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models S Radenkovic, R Budhraja, T Klein-Gunnewiek, AT King, TN Bhatia, ... Cell Reports 43 (3), 2024 | | 2024 |
| Probing the electrophysiological properties of patient-derived neurons across neurodevelopmental disorders B Latour, TK Gunnewiek, NN Kasri Phenotyping of Human iPSC-derived Neurons, 229-242, 2023 | | 2023 |
| Deficient Protein Glycosylation and Compromised Functional Integrity of PMM2 Deficient Neurons and Brain Organoids R Shah, R Budhraja, AT King, T Klein-Gunnewiek, S Radenkovic, ... Glycobiology 32 (11), 991-991, 2022 | | 2022 |
| Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m. 3243A> G heteroplasmy in iPSC-derived neurons AHA Verboven, TMK Gunnewiek, I Pelgrim, M Hogeweg, C Schoenmaker, ... Transcriptomic and functional phenotyping of human neurons: towards, 169, 2022 | | 2022 |
| Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips AHA Verboven, HHT Middelkamp, AGDS Vivas, C Schoenmaker, ... Transcriptomic and functional phenotyping of human neurons: towards, 209, 2022 | | 2022 |
| Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro AHA Verboven, B Mossink, EJH van Hugte, TMK Gunnewiek, G Parodi, ... Transcriptomic and functional phenotyping of human neurons: towards, 41, 2022 | | 2022 |
