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Teun Klein Gunnewiek
Teun Klein Gunnewiek
Phd researcher, RadboudUMC Nijmegen
Verified email at radboudumc.nl
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Cited by
Cited by
Year
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling
M Frega, K Linda, JM Keller, G Gümüş-Akay, B Mossink, JR van Rhijn, ...
Nature communications 10 (1), 4928, 2019
1292019
Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro
B Mossink, AHA Verboven, EJH van Hugte, TMK Gunnewiek, G Parodi, ...
Stem cell reports 16 (9), 2182-2196, 2021
812021
m. 3243A> G-induced mitochondrial dysfunction impairs human neuronal development and reduces neuronal network activity and synchronicity
TMK Gunnewiek, EJH Van Hugte, M Frega, GS Guardia, K Foreman, ...
Cell reports 31 (3), 2020
73*2020
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks
B Mossink, JR Van Rhijn, S Wang, K Linda, MR Vitale, JEM Zöller, ...
Molecular Psychiatry 27 (1), 1-18, 2022
672022
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders
K Linda, EI Lewerissa, AHA Verboven, M Gabriele, M Frega, ...
Autophagy 18 (2), 423-442, 2022
542022
MicroRNA-338 attenuates cortical neuronal outgrowth by modulating the expression of axon guidance genes
A Kos, T Klein-Gunnewiek, J Meinhardt, NFMO Loohuis, H van Bokhoven, ...
Molecular neurobiology 54, 3439-3452, 2017
282017
Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips
HHT Middelkamp, AHA Verboven, AG De Sá Vivas, C Schoenmaker, ...
Scientific reports 11 (1), 2281, 2021
232021
Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m. 3243A> G heteroplasmy in iPSC-derived neurons
TMK Gunnewiek, AHA Verboven, I Pelgrim, M Hogeweg, C Schoenmaker, ...
Stem Cell Reports 16 (9), 2197-2212, 2021
122021
Modulation of glucocorticoids by the serotonin transporter polymorphism: A narrative review
TMK Gunnewiek, JR Homberg, T Kozicz
Neuroscience & Biobehavioral Reviews 92, 338-349, 2018
112018
Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons
JR Van Rhijn, Y Shi, M Bormann, B Mossink, M Frega, H Recaioglu, ...
Neurobiology of disease 163, 105587, 2022
102022
Neuronal network dysfunction in a human model for Kleefstra syndrome mediated by enhanced NMDAR signaling
M Frega, K Linda, JM Keller, G Gümüş-Akay, B Mossink, JR van Rhijn, ...
bioRxiv, 585596, 2019
72019
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling. Nat. Commun. 10, 1–15
M Frega, K Linda, JM Keller, G Gümüsç-Akay, B Mossink, JR van Rhijn, ...
62019
KANSL1 deficiency causes neuronal dysfunction by oxidative stress-induced autophagy
K Linda, EII Lewerissa, AHA Verboven, M Gabriele, M Frega, ...
bioRxiv, 2020.08. 07.241257, 2020
32020
Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models
S Radenkovic, R Budhraja, T Klein-Gunnewiek, AT King, TN Bhatia, ...
Cell reports 43 (3), 2024
12024
Brain-on-a-chip-a neurophysiological model of MELAS disease and comorbid psychopathology
T Kozicz, T Klein-Gunnewiek, D Cassiman, T Nelson, R Rodenburg, ...
European Journal Of Human Genetics 27, 1161-1162, 2019
12019
Probing the electrophysiological properties of patient-derived neurons across neurodevelopmental disorders
B Latour, TK Gunnewiek, NN Kasri
Phenotyping of Human iPSC-derived Neurons, 229-242, 2023
2023
Deficient Protein Glycosylation and Compromised Functional Integrity of PMM2 Deficient Neurons and Brain Organoids
R Shah, R Budhraja, AT King, T Klein-Gunnewiek, S Radenkovic, ...
Glycobiology 32 (11), 991-991, 2022
2022
Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m. 3243A> G heteroplasmy in iPSC-derived neurons
AHA Verboven, TMK Gunnewiek, I Pelgrim, M Hogeweg, C Schoenmaker, ...
Transcriptomic and functional phenotyping of human neurons: towards, 169, 2022
2022
Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips
AHA Verboven, HHT Middelkamp, AGDS Vivas, C Schoenmaker, ...
Transcriptomic and functional phenotyping of human neurons: towards, 209, 2022
2022
Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro
AHA Verboven, B Mossink, EJH van Hugte, TMK Gunnewiek, G Parodi, ...
Transcriptomic and functional phenotyping of human neurons: towards, 41, 2022
2022
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