| Clinical pharmacology of 5-fluorouracil RB Diasio, BE Harris Clinical pharmacokinetics 16, 215-237, 1989 | 1182 | 1989 |
| Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase D Salonga, KD Danenberg, M Johnson, R Metzger, S Groshen, ... Clinical Cancer Research 6 (4), 1322-1327, 2000 | 1109 | 2000 |
| Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile GD Heggie, JP Sommadossi, DS Cross, WJ Huster, RB Diasio Cancer research 47 (8), 2203-2206, 1987 | 921 | 1987 |
| Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity. RB Diasio, TL Beavers, JT Carpenter The Journal of clinical investigation 81 (1), 47-51, 1988 | 583 | 1988 |
| Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels … BE Harris, R Song, S Soong, RB Diasio Cancer research 50 (1), 197-201, 1990 | 563 | 1990 |
| Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing: 2017 update U Amstutz, LM Henricks, SM Offer, J Barbarino, JHM Schellens, JJ Swen, ... Clinical Pharmacology & Therapeutics 103 (2), 210-216, 2018 | 517 | 2018 |
| Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks WE Dismukes, G Cloud, HA Gallis, TM Kerkering, G Medoff, PC Craven, ... New England Journal of Medicine 317 (6), 334-341, 1987 | 509 | 1987 |
| Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical … Z Lu, R Zhang, RB Diasio Cancer research 53 (22), 5433-5438, 1993 | 484 | 1993 |
| Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction MR Johnson, K Wang, JB Smith, MJ Heslin, RB Diasio Analytical biochemistry 278 (2), 175-184, 2000 | 421 | 2000 |
| A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general … AC Antoniou, X Wang, ZS Fredericksen, L McGuffog, R Tarrell, ... Nature genetics 42 (10), 885-892, 2010 | 406 | 2010 |
| Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing KE Caudle, CF Thorn, TE Klein, JJ Swen, HL McLeod, RB Diasio, ... Clinical Pharmacology & Therapeutics 94 (6), 640-645, 2013 | 396 | 2013 |
| Method of down-regulating gene expression S Agrawal, RB Diasio, R Zhang US Patent 5,591,721, 1997 | 366* | 1997 |
| A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer CA Haiman, GK Chen, CM Vachon, F Canzian, A Dunning, RC Millikan, ... Nature genetics 43 (12), 1210-1214, 2011 | 348 | 2011 |
| The continuum of care: a paradigm for the management of metastatic colorectal cancer RM Goldberg, ML Rothenberg, E Van Cutsem, AB Benson III, CD Blanke, ... The oncologist 12 (1), 38-50, 2007 | 317 | 2007 |
| Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil MR Johnson, A Hageboutros, K Wang, L High, JB Smith, RB Diasio Clinical Cancer Research 5 (8), 2006-2011, 1999 | 309 | 1999 |
| Histone deacetylase inhibitors: current status and overview of recent clinical trials X Ma, HH Ezzeldin, RB Diasio Drugs 69, 1911-1934, 2009 | 307 | 2009 |
| Severe 5‐fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome BE Harris, JT Carpenter, RB Diasio Cancer 68 (3), 499-501, 1991 | 302 | 1991 |
| Toxicity of amphotericin B plus flucytosine in 194 patients with cryptococcal meningitis AM Stamm, RB Diasio, WE Dismukes, S Shadomy, GA Cloud, CA Bowles, ... The American journal of medicine 83 (2), 236-242, 1987 | 290 | 1987 |
| Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA: amino acid N-acyltransferase. CN Falany, MR Johnson, S Barnes, RB Diasio Journal of Biological Chemistry 269 (30), 19375-19379, 1994 | 265 | 1994 |
| Severe neurotoxicity following 5-fluorouracil-based chemotherapy in a patient with dihydropyrimidine dehydrogenase deficiency. CH Takimoto, ZH Lu, R Zhang, MD Liang, LV Larson, LR Cantilena Jr, ... Clinical cancer research: an official journal of the American Association …, 1996 | 220 | 1996 |
