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Tanja Gruber
Tanja Gruber
Geverifieerd e-mailadres voor stjude.org
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Germline mutations in predisposition genes in pediatric cancer
J Zhang, MF Walsh, G Wu, MN Edmonson, TA Gruber, J Easton, ...
New England Journal of Medicine 373 (24), 2336-2346, 2015
12192015
The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias
AK Andersson, J Ma, J Wang, X Chen, AL Gedman, J Dang, J Nakitandwe, ...
Nature genetics 47 (4), 330-337, 2015
4792015
Diverse and targetable kinase alterations drive histiocytic neoplasms
EL Diamond, BH Durham, J Haroche, Z Yao, J Ma, SA Parikh, Z Wang, ...
Cancer discovery 6 (2), 154-165, 2016
4462016
The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes
R Huether, L Dong, X Chen, G Wu, M Parker, L Wei, J Ma, MN Edmonson, ...
Nature communications 5 (1), 3630, 2014
4072014
The genomic landscape of juvenile myelomonocytic leukemia
E Stieglitz, AN Taylor-Weiner, TY Chang, LC Gelston, YD Wang, T Mazor, ...
Nature genetics 47 (11), 1326-1333, 2015
2752015
The genomic landscape of core-binding factor acute myeloid leukemias
ZJ Faber, X Chen, AL Gedman, K Boggs, J Cheng, J Ma, I Radtke, ...
Nature genetics 48 (12), 1551-1556, 2016
2592016
An Inv (16)(p13. 3q24. 3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia
TA Gruber, AL Gedman, J Zhang, CS Koss, S Marada, HQ Ta, SC Chen, ...
Cancer cell 22 (5), 683-697, 2012
2592012
Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study
CH Pui, D Pei, E Coustan-Smith, S Jeha, C Cheng, WP Bowman, ...
The lancet oncology 16 (4), 465-474, 2015
2292015
Improved CNS control of childhood acute lymphoblastic leukemia without cranial irradiation: St Jude Total Therapy Study 16
S Jeha, D Pei, J Choi, C Cheng, JT Sandlund, E Coustan-Smith, ...
Journal of Clinical Oncology 37 (35), 3377, 2019
1972019
Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes
JDE De Rooij, C Branstetter, J Ma, Y Li, MP Walsh, J Cheng, A Obulkasim, ...
Nature genetics 49 (3), 451-456, 2017
1892017
Clinical impact of minimal residual disease in children with different subtypes of acute lymphoblastic leukemia treated with response-adapted therapy
CH Pui, D Pei, SC Raimondi, E Coustan-Smith, S Jeha, C Cheng, ...
Leukemia 31 (2), 333-339, 2017
1722017
Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome
M Rusch, J Nakitandwe, S Shurtleff, S Newman, Z Zhang, MN Edmonson, ...
Nature communications 9 (1), 3962, 2018
1692018
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia
S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ...
The Journal of clinical investigation 130 (2), 981-997, 2020
1642020
A revised definition for cure of childhood acute lymphoblastic leukemia
CH Pui, D Pei, D Campana, C Cheng, JT Sandlund, WP Bowman, ...
Leukemia 28 (12), 2336-2343, 2014
1622014
Pre–B cell receptor–mediated cell cycle arrest in Philadelphia chromosome–positive acute lymphoblastic leukemia requires IKAROS function
D Trageser, I Iacobucci, R Nahar, C Duy, G von Levetzow, L Klemm, ...
Journal of Experimental Medicine 206 (8), 1739-1753, 2009
1512009
The biology of pediatric acute megakaryoblastic leukemia
TA Gruber, JR Downing
Blood, The Journal of the American Society of Hematology 126 (8), 943-949, 2015
1472015
Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease–directed therapy
S Jeha, J Choi, KG Roberts, D Pei, E Coustan-Smith, H Inaba, JE Rubnitz, ...
Blood cancer discovery 2 (4), 326-337, 2021
932021
St. Jude Children’s Research Hospital–Washington University pediatric cancer genome project. The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic …
AK Andersson, J Ma, J Wang, X Chen, AL Gedman, J Dang, J Nakitandwe, ...
Nat Genet 47 (4), 330-337, 2015
792015
A six-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia
AH Elsayed, R Rafiee, X Cao, S Raimondi, JR Downing, R Ribeiro, Y Fan, ...
Leukemia 34 (3), 735-745, 2020
652020
Prognostic impact of t (16; 21)(p11; q22) and t (16; 21)(q24; q22) in pediatric AML: a retrospective study by the I-BFM Study Group
S Noort, M Zimmermann, D Reinhardt, W Cuccuini, M Pigazzi, J Smith, ...
Blood, The Journal of the American Society of Hematology 132 (15), 1584-1592, 2018
602018
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Artikelen 1–20