Thomas Hurd
Thomas Hurd
University of Toronto, Department of Molecular Genetics
Verified email at - Homepage
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Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology
MF Ross, GF Kelso, FH Blaikie, AM James, HM Cocheme, A Filipovska, ...
Biochemistry (Moscow) 70, 222-230, 2005
Redox regulation of cell migration and adhesion
TR Hurd, M DeGennaro, R Lehmann
Trends in cell biology 22 (2), 107-115, 2012
Cysteine residues exposed on protein surfaces are the dominant intramitochondrial thiol and may protect against oxidative damage
R Requejo, TR Hurd, NJ Costa, MP Murphy
The FEBS journal 277 (6), 1465-1480, 2010
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury
TA Prime, FH Blaikie, C Evans, SM Nadtochiy, AM James, CC Dahm, ...
Proceedings of the National Academy of Sciences 106 (26), 10764-10769, 2009
Glutathionylation of mitochondrial proteins
TR Hurd, NJ Costa, CC Dahm, SM Beer, SE Brown, A Filipovska, ...
Antioxidants & redox signaling 7 (7-8), 999-1010, 2005
Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing …
TR Hurd, R Requejo, A Filipovska, S Brown, TA Prime, AJ Robinson, ...
Journal of Biological Chemistry 283 (36), 24801-24815, 2008
Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline
T Lieber, SP Jeedigunta, JM Palozzi, R Lehmann, TR Hurd
Nature 570 (7761), 380-384, 2019
Detection of reactive oxygen species-sensitive thiol proteins by redox difference gel electrophoresis: implications for mitochondrial redox signaling
TR Hurd, TA Prime, ME Harbour, KS Lilley, MP Murphy
Journal of Biological Chemistry 282 (30), 22040-22051, 2007
Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial …
ET Chouchani, TR Hurd, SM Nadtochiy, PS Brookes, IM Fearnley, ...
Biochemical Journal 430 (1), 49-59, 2010
ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation
FK Teixeira, CG Sanchez, TR Hurd, JRK Seifert, B Czech, JB Preall, ...
Nature cell biology 17 (5), 689-696, 2015
Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells
KE Kistler, T Trcek, TR Hurd, R Chen, FX Liang, J Sall, M Kato, ...
Elife 7, e37949, 2018
Disulphide formation on mitochondrial protein thiols
TR Hurd, A Filipovska, NJ Costa, CC Dahm, MP Murphy
Biochemical Society Transactions 33 (6), 1390-1393, 2005
Long Oskar controls mitochondrial inheritance in Drosophila melanogaster
TR Hurd, B Herrmann, J Sauerwald, J Sanny, M Grosch, R Lehmann
Developmental cell 39 (5), 560-571, 2016
Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species
TR Hurd, Y Collins, I Abakumova, ET Chouchani, B Baranowski, ...
Journal of Biological Chemistry 287 (42), 35153-35160, 2012
Peroxiredoxin stabilization of DE-cadherin promotes primordial germ cell adhesion
M DeGennaro, TR Hurd, DE Siekhaus, B Biteau, H Jasper, R Lehmann
Developmental cell 20 (2), 233-243, 2011
Mitochondrial DNA purifying selection in mammals and invertebrates
JM Palozzi, SP Jeedigunta, TR Hurd
Journal of molecular biology 430 (24), 4834-4848, 2018
Curly Encodes Dual Oxidase, Which Acts with Heme Peroxidase Curly Su to Shape the Adult Drosophila Wing
TR Hurd, FX Liang, R Lehmann
PLoS genetics 11 (11), e1005625, 2015
Measuring mitochondrial protein thiol redox state
R Requejo, ET Chouchani, TR Hurd, KE Menger, MB Hampton, ...
Methods in enzymology 474, 123-147, 2010
Biological systems relevant for redox signaling and control
TR Hurd, MP Murphy
Redox signaling and regulation in biology and medicine, 13-43, 2009
Measuring redox changes to mitochondrial protein thiols with redox difference gel electrophoresis (Redox‐Dige)
TR Hurd, AM James, KS Lilley, MP Murphy
Methods in enzymology 456, 343-361, 2009
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