Karien Bloem
Karien Bloem
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Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells
JJ García-Vallejo, M Ambrosini, A Overbeek, WE van Riel, K Bloem, ...
Molecular immunology 53 (4), 387-397, 2013
Systematic comparison of drug-tolerant assays for anti-drug antibodies in a cohort of adalimumab-treated rheumatoid arthritis patients
K Bloem, A van Leeuwen, G Verbeek, MT Nurmohamed, GJ Wolbink, ...
Journal of immunological methods 418, 29-38, 2015
Defining the therapeutic range for adalimumab and predicting response in psoriasis: a multicenter prospective observational cohort study
N Wilkinson, T Tsakok, N Dand, K Bloem, M Duckworth, D Baudry, ...
Journal of Investigative Dermatology 139 (1), 115-123, 2019
Immunogenicity of therapeutic antibodies: monitoring antidrug antibodies in a clinical context
K Bloem, B Hernández-Breijo, A Martínez-Feito, T Rispens
Therapeutic drug monitoring 39 (4), 327-332, 2017
BODIPY-labeled DC-SIGN-targeting glycodendrons efficiently internalize and route to lysosomes in human dendritic cells
R Ribeiro-Viana, JJ Garcia-Vallejo, D Collado, E Perez-Inestrosa, ...
Biomacromolecules 13 (10), 3209-3219, 2012
DCIR interacts with ligands from both endogenous and pathogenic origin
K Bloem, IM Vuist, M van den Berk, EJ Klaver, I van Die, LMJ Knippels, ...
Immunology letters 158 (1-2), 33-41, 2014
Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain
K Bloem, IM Vuist, AJ van der Plas, LMJ Knippels, J Garssen, ...
PLoS One 8 (6), e66266, 2013
Identification and characterization of a complete carnitine biosynthesis pathway in Candida albicans
K Strijbis, CWT Van Roermund, GP Hardy, J Van den Burg, K Bloem, ...
The FASEB Journal 23 (8), 2349-2359, 2009
Capillary blood microsampling to determine serum biopharmaceutical concentration: Mitra® microsampler vs dried blood spot
K Bloem, T Schaap, R Boshuizen, EL Kneepkens, GJ Wolbink, A Vries, ...
Bioanalysis 10 (11), 815-823, 2018
Dynamics of circulating TNF during adalimumab treatment using a drug-tolerant TNF assay
LC Berkhout, MJ l’Ami, J Ruwaard, MH Hart, PO Heer, K Bloem, ...
Science Translational Medicine 11 (477), eaat3356, 2019
Association of serum ustekinumab levels with clinical response in psoriasis
T Tsakok, N Wilson, N Dand, FC Loeff, K Bloem, D Baudry, M Duckworth, ...
JAMA dermatology 155 (11), 1235-1243, 2019
The consequences of multiple simultaneous C-type lectin–ligand interactions: DCIR alters the endo-lysosomal routing of DC-SIGN
JJ García-Vallejo, K Bloem, LMJ Knippels, J Garssen, SJ van Vliet, ...
Frontiers in Immunology 6, 132847, 2015
Dried blood spots from finger prick facilitate therapeutic drug monitoring of adalimumab and anti‐adalimumab in patients with inflammatory diseases
EL Kneepkens, MF Pouw, GJ Wolbink, T Schaap, MT Nurmohamed, ...
British journal of clinical pharmacology 83 (11), 2474-2484, 2017
Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to …
K Bloem, JJ García-Vallejo, IM Vuist, BA Cobb, SJ van Vliet, Y Van Kooyk
Frontiers in immunology 4, 103, 2013
Dried blood samples can support monitoring of infliximab concentrations in patients with inflammatory bowel disease: a clinical validation
SE Berends, GRAM D'Haens, T Schaap, A de Vries, T Rispens, K Bloem, ...
British journal of clinical pharmacology 85 (7), 1544-1551, 2019
Toll-like receptor 4 triggering promotes cytosolic routing of DC-SIGN-targeted antigens for presentation on MHC class I
SK Horrevorts, S Duinkerken, K Bloem, P Secades, H Kalay, RJ Musters, ...
Frontiers in immunology 9, 1231, 2018
Predictive value of serum infliximab levels at induction phase in rheumatoid arthritis patients
T Jurado, C Plasencia-Rodríguez, A Martínez-Feito, V Navarro-Compán, ...
The Open Rheumatology Journal 11, 75, 2017
Monitoring of adalimumab concentrations at home in patients with inflammatory bowel disease using dried blood samples
SE Berends, K Bloem, A de Vries, T Schaap, T Rispens, AS Strik, ...
Therapeutic drug monitoring 42 (2), 289-294, 2020
Comprehensive evaluation of microneedle‐based intradermal adalimumab delivery vs. subcutaneous administration: results of a randomized controlled clinical trial
J Jacobse, W Ten Voorde, A Tandon, SG Romeijn, HW Grievink, ...
British journal of clinical pharmacology 87 (8), 3162-3176, 2021
Using real‐world data to guide ustekinumab dosing strategies for psoriasis: a prospective pharmacokinetic‐pharmacodynamic study
S Pan, T Tsakok, N Dand, DO Lonsdale, FC Loeff, K Bloem, A de Vries, ...
Clinical and Translational Science 13 (2), 400-409, 2020
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