NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction E Gaude, C Schmidt, PA Gammage, A Dugourd, T Blacker, SP Chew, ... Molecular cell 69 (4), 581-593. e7, 2018 | 214 | 2018 |
Fumarate hydratase in cancer: A multifaceted tumour suppressor C Schmidt, M Sciacovelli, C Frezza Seminars in cell & developmental biology 98, 15-25, 2020 | 114 | 2020 |
Metabolic drivers in hereditary cancer syndromes M Sciacovelli, C Schmidt, ER Maher, C Frezza Annual Review of Cancer Biology 4, 77-97, 2020 | 49 | 2020 |
Exosomes as secondary inductive signals involved in kidney organogenesis M Krause, A Rak-Raszewska, F Naillat, U Saarela, C Schmidt, ... Journal of extracellular vesicles 7 (1), 1422675, 2018 | 40 | 2018 |
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression M Sciacovelli, A Dugourd, LV Jimenez, M Yang, E Nikitopoulou, ... Nature communications 13 (1), 7830, 2022 | 10 | 2022 |
Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke A Mottahedin, HA Prag, A Dannhorn, R Mair, C Schmidt, M Yang, ... Redox Biology 59, 102600, 2023 | 9 | 2023 |
HIRA loss transforms FH-deficient cells L Valcarcel-Jimenez, C Rogerson, C Yong, C Schmidt, M Yang, ... Science advances 8 (42), eabq8297, 2022 | 5 | 2022 |
Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progression M Sciacovelli, A Dugourd, LV Jimenez, M Yang, E Nikitopoulou, ... BioRxiv, 2021.09. 17.460635, 2021 | 5 | 2021 |
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes C Moschandrea, V Kondylis, I Evangelakos, M Herholz, F Schneider, ... Nature 625 (7994), 385-392, 2024 | 4 | 2024 |
Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells R Harris, M Yang, C Schmidt, C Royet, S Singh, A Natarajan, M Morris, ... Journal of Cell Biology 221 (7), e202203095, 2022 | 4 | 2022 |
FOXA2 controls the anti-oxidant response in FH-deficient cells C Rogerson, M Sciacovelli, LA Maddalena, A Pouikli, ... Cell Reports 42 (7), 2023 | 2 | 2023 |
Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease RE Jones, AV Gruszczyk, C Schmidt, DJ Hammersley, L Mach, M Lee, ... Nature Cardiovascular Research 2 (8), 733-745, 2023 | 1 | 2023 |
SiRCle (Signature Regulatory Clustering) model integration reveals mechanisms of phenotype regulation in renal cancer A Mora, C Schmidt, B Balderson, C Frezza, M Bodén bioRxiv, 2022.07. 02.498058, 2022 | 1 | 2022 |
ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation OI Coleman, A Sorbie, S Bierwith, J Kövilein, M von Stern, N Köhler, ... bioRxiv, 2023.11. 03.565267, 2023 | | 2023 |
MetalinksDB: a flexible and contextualizable resource of metabolite-protein interactions EB Farr, D Dimitrov, D Turei, C Schmidt, S Lobentanzer, A Dugourd, ... bioRxiv, 2023.12. 30.573715, 2023 | | 2023 |
The generation of a human cell line to elucidate the role of Fumarate Hydratase loss in cancer C Schmidt | | 2021 |