| Organoid models of human and mouse ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ... Cell 160 (1), 324-338, 2015 | 1900 | 2015 |
| Lgr5+ ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro N Barker, M Huch, P Kujala, M van de Wetering, HJ Snippert, JH van Es, ... Cell stem cell 6 (1), 25-36, 2010 | 1728 | 2010 |
| In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration M Huch, C Dorrell, SF Boj, JH Van Es, VSW Li, M Van De Wetering, ... Nature 494 (7436), 247-250, 2013 | 1562 | 2013 |
| Long-term culture of genome-stable bipotent stem cells from adult human liver M Huch, H Gehart, R Van Boxtel, K Hamer, F Blokzijl, MMA Verstegen, ... Cell 160 (1), 299-312, 2015 | 1445 | 2015 |
| Human primary liver cancer–derived organoid cultures for disease modeling and drug screening L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarró, ... Nature medicine 23 (12), 1424-1435, 2017 | 1127 | 2017 |
| Tissue-specific mutation accumulation in human adult stem cells during life F Blokzijl, J De Ligt, M Jager, V Sasselli, S Roerink, N Sasaki, M Huch, ... Nature 538 (7624), 260-264, 2016 | 882 | 2016 |
| In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection S Bartfeld, T Bayram, M van de Wetering, M Huch, H Begthel, P Kujala, ... Gastroenterology 148 (1), 126-136. e6, 2015 | 763 | 2015 |
| Unlimited in vitro expansion of adult bi‐potent pancreas progenitors through the Lgr5/R‐spondin axis M Huch, P Bonfanti, SF Boj, T Sato, CJM Loomans, M Van De Wetering, ... The EMBO journal 32 (20), 2708-2721, 2013 | 705 | 2013 |
| Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation L Broutier, A Andersson-Rolf, CJ Hindley, SF Boj, H Clevers, BK Koo, ... Nature protocols 11 (9), 1724-1743, 2016 | 665 | 2016 |
| Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium DE Stange, BK Koo, M Huch, G Sibbel, O Basak, A Lyubimova, P Kujala, ... Cell 155 (2), 357-368, 2013 | 528 | 2013 |
| Modeling mouse and human development using organoid cultures M Huch, BK Koo Development 142 (18), 3113-3125, 2015 | 521 | 2015 |
| The hope and the hype of organoid research M Huch, JA Knoblich, MP Lutolf, A Martinez-Arias Development 144 (6), 938-941, 2017 | 384 | 2017 |
| Genome sequencing of normal cells reveals developmental lineages and mutational processes S Behjati, M Huch, R Van Boxtel, W Karthaus, DC Wedge, AU Tamuri, ... Nature 513 (7518), 422-425, 2014 | 370 | 2014 |
| Controlled gene expression in primary Lgr5 organoid cultures BK Koo, DE Stange, T Sato, W Karthaus, HF Farin, M Huch, JH Van Es, ... Nature methods 9 (1), 81-83, 2012 | 360 | 2012 |
| Disease modelling in human organoids MA Lancaster, M Huch Disease models & mechanisms 12 (7), dmm039347, 2019 | 300 | 2019 |
| Liver organoids: from basic research to therapeutic applications N Prior, P Inacio, M Huch Gut 68 (12), 2228-2237, 2019 | 280 | 2019 |
| Lgr5+ ve stem/progenitor cells contribute to nephron formation during kidney development N Barker, MB Rookmaaker, P Kujala, A Ng, M Leushacke, H Snippert, ... Cell reports 2 (3), 540-552, 2012 | 252 | 2012 |
| Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand SF Boj, JH van Es, M Huch, VSW Li, A José, P Hatzis, M Mokry, ... Cell 151 (7), 1595-1607, 2012 | 247 | 2012 |
| Organoids Z Zhao, X Chen, AM Dowbaj, A Sljukic, K Bratlie, L Lin, ELS Fong, ... Nature Reviews Methods Primers 2 (1), 94, 2022 | 220 | 2022 |
| The balancing act of the liver: tissue regeneration versus fibrosis L Cordero-Espinoza, M Huch The Journal of clinical investigation 128 (1), 85-96, 2018 | 201 | 2018 |
