Jean-Louis Mergny
Jean-Louis Mergny
Ecole Polytechnique, Palaiseau, France
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Following G‐quartet formation by UV‐spectroscopy
JL Mergny, AT Phan, L Lacroix
FEBS letters 435 (1), 74-78, 1998
Analysis of thermal melting curves
JL Mergny, L Lacroix
Oligonucleotides 13 (6), 515-537, 2003
Targeting telomeres and telomerase
A De Cian, L Lacroix, C Douarre, N Temime-Smaali, C Trentesaux, ...
Biochimie 90 (1), 131-155, 2008
Natural and pharmacological regulation of telomerase
JL Mergny, JF Riou, P Mailliet, MP Teulade-Fichou, E Gilson
Nucleic Acids Research 30 (4), 839-865, 2002
Human telomeric DNA: G‐quadruplex, i‐motif and Watson–Crick double helix
AT Phan, JL Mergny
Nucleic acids research 30 (21), 4618-4625, 2002
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
JF Riou, L Guittat, P Mailliet, A Laoui, E Renou, O Petitgenet, ...
Proceedings of the National Academy of Sciences 99 (5), 2672-2677, 2002
G-quadruplex DNA: a target for drug design
JL Mergny, C Hélène
Nature medicine 4 (12), 1366-1367, 1998
DNA duplex–quadruplex exchange as the basis for a nanomolecular machine
P Alberti, JL Mergny
Proceedings of the National Academy of Sciences 100 (4), 1569-1573, 2003
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay
JL Mergny, L Lacroix, MP Teulade-Fichou, C Hounsou, L Guittat, ...
Proceedings of the National Academy of Sciences 98 (6), 3062-3067, 2001
Fluorescence-based melting assays for studying quadruplex ligands
A De Cian, L Guittat, M Kaiser, B Saccà, S Amrane, A Bourdoncle, ...
Methods 42 (2), 183-195, 2007
Thermal difference spectra: a specific signature for nucleic acid structures
JL Mergny, J Li, L Lacroix, S Amrane, JB Chaires
Nucleic acids research 33 (16), e138-e138, 2005
Triple helix-specific ligands
JL Mergny, G Duval-Valentin, CH Nguyen, L Perrouault, B Faucon, ...
Science 256 (5064), 1681-1684, 1992
Highly efficient G-quadruplex recognition by bisquinolinium compounds
A De Cian, E DeLemos, JL Mergny, MP Teulade-Fichou, D Monchaud
Journal of the American Chemical Society 129 (7), 1856-1857, 2007
How long is too long? Effects of loop size on G-quadruplex stability
A Guedin, J Gros, P Alberti, JL Mergny
Nucleic acids research 38 (21), 7858-7868, 2010
The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo
C Ribeyre, J Lopes, JB Boulé, A Piazza, A Guédin, VA Zakian, JL Mergny, ...
PLoS Genet 5 (5), e1000475, 2009
Kinetics of tetramolecular quadruplexes
JL Mergny, A De Cian, A Ghelab, B Sacca, L Lacroix
Nucleic acids research 33 (1), 81-94, 2005
Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into an i-motif
JL Leroy, M Gueron, JL Mergny, C Helene
Nucleic acids research 22 (9), 1600-1606, 1994
Fluorescence resonance energy transfer as a probe for G‐quartet formation by a telomeric repeat
JL Mergny, JC Maurizot
ChemBioChem 2 (2), 124-132, 2001
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action
A De Cian, G Cristofari, P Reichenbach, E De Lemos, D Monchaud, ...
Proceedings of the National Academy of Sciences 104 (44), 17347-17352, 2007
Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes
F Koeppel, JF Riou, A Laoui, P Mailliet, PB Arimondo, D Labit, ...
Nucleic Acids Research 29 (5), 1087-1096, 2001
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