Catherine Postic
Catherine Postic
Institut Cochin
Verified email at
Cited by
Cited by
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
MD Michael, RN Kulkarni, C Postic, SF Previs, GI Shulman, ...
Molecular cell 6 (1), 87-97, 2000
Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes
RN Kulkarni, JC Brüning, JN Winnay, C Postic, MA Magnuson, CR Kahn
Cell 96 (3), 329-339, 1999
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic β cell-specific gene knock-outs using Cre recombinase
C Postic, M Shiota, KD Niswender, TL Jetton, Y Chen, JM Moates, ...
Journal of Biological Chemistry 274 (1), 305-315, 1999
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice
C Postic, J Girard
The Journal of clinical investigation 118 (3), 829-838, 2008
Role of the liver in the control of carbohydrate and lipid homeostasis
C Postic, R Dentin, J Girard
Diabetes & metabolism 30 (5), 398-408, 2004
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression
R Dentin, JP Pégorier, F Benhamed, F Foufelle, P Ferré, V Fauveau, ...
Journal of Biological Chemistry 279 (19), 20314-20326, 2004
Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice
R Dentin, F Benhamed, I Hainault, V Fauveau, F Foufelle, JRB Dyck, ...
Diabetes 55 (8), 2159-2170, 2006
DNA excision in liver by an albumin‐Cre transgene occurs progressively with age
C Postic, MA Magnuson
genesis 26 (2), 149-150, 2000
Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid …
R Dentin, J Girard, C Postic
Biochimie 87 (1), 81-86, 2005
Brain glucagon-like peptide–1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
C Knauf, PD Cani, C Perrin, MA Iglesias, JF Maury, E Bernard, ...
The Journal of clinical investigation 115 (12), 3554-3563, 2005
Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation
R Dentin, F Benhamed, JP Pégorier, F Foufelle, B Viollet, S Vaulont, ...
The Journal of clinical investigation 115 (10), 2843-2854, 2005
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
A Montagner, A Polizzi, E Fouché, S Ducheix, Y Lippi, F Lasserre, ...
Gut 65 (7), 1202-1214, 2016
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
F Benhamed, PD Denechaud, M Lemoine, C Robichon, M Moldes, ...
The Journal of clinical investigation 122 (6), 2176-2194, 2012
The role of the lipogenic pathway in the development of hepatic steatosis
C Postic, J Girard
Diabetes & metabolism 34 (6), 643-648, 2008
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
J Bricambert, J Miranda, F Benhamed, J Girard, C Postic, R Dentin
The Journal of clinical investigation 120 (12), 4316-4331, 2010
ChREBP, a transcriptional regulator of glucose and lipid metabolism
C Postic, R Dentin, PD Denechaud, J Girard
Annu. Rev. Nutr. 27, 179-192, 2007
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
L Hoyles, JM Fernandez-Real, M Federici, M Serino, J Abbott, ...
Nature medicine 24 (7), 1070-1080, 2018
Hepatocyte-specific mutation establishes retinoid X receptor α as a heterodimeric integrator of multiple physiological processes in the liver
YJY Wan, D An, Y Cai, JJ Repa, T Hung-Po Chen, M Flores, C Postic, ...
Molecular and cellular biology 20 (12), 4436-4444, 2000
Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism
P She, M Shiota, KD Shelton, R Chalkley, C Postic, MA Magnuson
Molecular and cellular biology 20 (17), 6508-6517, 2000
ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver
PD Denechaud, P Bossard, JMA Lobaccaro, L Millatt, B Staels, J Girard, ...
The Journal of clinical investigation 118 (3), 956-964, 2008
The system can't perform the operation now. Try again later.
Articles 1–20