Suivre
Juan F. Linares
Juan F. Linares
Instructor, Weill Cornell Medicine
Adresse e-mail validée de med.cornell.edu
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Antibiotics as intermicrobial signaling agents instead of weapons
JF Linares, I Gustafsson, F Baquero, JL Martinez
Proceedings of the National Academy of Sciences 103 (51), 19484-19489, 2006
8232006
The signaling adaptor p62 is an important NF-κB mediator in tumorigenesis
A Duran, JF Linares, AS Galvez, K Wikenheiser, JM Flores, MT Diaz-Meco, ...
Cancer cell 13 (4), 343-354, 2008
6412008
p62 is a key regulator of nutrient sensing in the mTORC1 pathway
A Duran, R Amanchy, JF Linares, J Joshi, S Abu-Baker, A Porollo, ...
Molecular cell 44 (1), 134-146, 2011
5372011
A global view of antibiotic resistance
JL Martinez, A Fajardo, L Garmendia, A Hernandez, JF Linares, ...
FEMS microbiology reviews 33 (1), 44-65, 2008
4232008
p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells
A Umemura, F He, K Taniguchi, H Nakagawa, S Yamachika, ...
Cancer cell 29 (6), 935-948, 2016
4192016
A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis
SR Alonso, L Tracey, P Ortiz, B Pérez-Gómez, J Palacios, M Pollán, ...
Cancer research 67 (7), 3450-3460, 2007
3772007
K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells
JF Linares, A Duran, T Yajima, M Pasparakis, J Moscat, MT Diaz-Meco
Molecular cell 51 (3), 283-296, 2013
2602013
Fitness of in vitro selected Pseudomonas aeruginosanalB and nfxB multidrug resistant mutants
P Sánchez, JF Linares, B Ruiz-Díez, E Campanario, A Navas, F Baquero, ...
Journal of Antimicrobial Chemotherapy 50 (5), 657-664, 2002
2432002
Overexpression of the Multidrug Efflux Pumps MexCD-OprJ and MexEF-OprN Is Associated with a Reduction of Type III Secretion in Pseudomonas aeruginosa
JF Linares, JA López, E Camafeita, JP Albar, F Rojo, JL Martínez
Journal of bacteriology 187 (4), 1384-1391, 2005
2162005
The global regulator Crc modulates metabolism, susceptibility to antibiotics and virulence in Pseudomonas aeruginosa
JF Linares, R Moreno, A Fajardo, L Martínez‐Solano, R Escalante, F Rojo, ...
Environmental microbiology 12 (12), 3196-3212, 2010
1732010
The Pseudomonas putida Crc Global Regulator Controls the Expression of Genes from Several Chromosomal Catabolic Pathways for Aromatic Compounds
G Morales, JF Linares, A Beloso, JP Albar, JL Martínez, F Rojo
Journal of bacteriology 186 (5), 1337-1344, 2004
1602004
Increased serine and one-carbon pathway metabolism by PKCλ/ι deficiency promotes neuroendocrine prostate cancer
M Reina-Campos, JF Linares, A Duran, T Cordes, A L'Hermitte, MG Badur, ...
Cancer Cell 35 (3), 385-400. e9, 2019
1572019
Overproduction of the multidrug efflux pump MexEF‐OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in …
J Olivares, C Alvarez‐Ortega, JF Linares, F Rojo, T Köhler, JL Martínez
Environmental microbiology 14 (8), 1968-1981, 2012
1242012
Amino acid activation of mTORC1 by a PB1-domain-driven kinase complex cascade
JF Linares, A Duran, M Reina-Campos, P Aza-Blanc, A Campos, J Moscat, ...
Cell reports 12 (8), 1339-1352, 2015
1152015
Protein kinase Cζ represses the interleukin-6 promoter and impairs tumorigenesis in vivo
AS Galvez, A Duran, JF Linares, P Pathrose, EA Castilla, S Abu-Baker, ...
Molecular and cellular biology 29 (1), 104-115, 2009
992009
Par‐4 inhibits Akt and suppresses Ras‐induced lung tumorigenesis
J Joshi, PJ Fernandez‐Marcos, A Galvez, R Amanchy, JF Linares, ...
The EMBO journal 27 (16), 2181-2193, 2008
992008
ATF4-induced metabolic reprograming is a synthetic vulnerability of the p62-deficient tumor stroma
JF Linares, T Cordes, A Duran, M Reina-Campos, T Valencia, CS Ahn, ...
Cell metabolism 26 (6), 817-829. e6, 2017
932017
Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation
JF Linares, R Amanchy, MT Diaz-Meco, J Moscat
Molecular and cellular biology 31 (1), 105-117, 2011
892011
PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression
Y Kudo, M Sugimoto, E Arias, H Kasashima, T Cordes, JF Linares, ...
Cancer cell 38 (2), 247-262. e11, 2020
862020
Repression of intestinal stem cell function and tumorigenesis through direct phosphorylation of β-catenin and Yap by PKCζ
V Llado, Y Nakanishi, A Duran, M Reina-Campos, PM Shelton, JF Linares, ...
Cell reports 10 (5), 740-754, 2015
822015
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