| Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration R Ishimura, G Nagy, I Dotu, H Zhou, XL Yang, P Schimmel, S Senju, ... Science 345 (6195), 455-459, 2014 | 438 | 2014 |
| Inhibiting Ferroptosis through Disrupting the NCOA4–FTH1 Interaction: A New Mechanism of Action Y Fang, X Chen, Q Tan, H Zhou, J Xu, Q Gu ACS Central Science 7, 980-989, 2021 | 193 | 2021 |
| ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase H Zhou, L Sun, XL Yang, P Schimmel Nature 494 (7435), 121-124, 2013 | 173 | 2013 |
| CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase W He, G Bai, H Zhou, N Wei, NM White, J Lauer, H Liu, Y Shi, CD Dumitru, ... Nature 526 (7575), 710-714, 2015 | 156 | 2015 |
| The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs JD Herman, LR Pepper, JF Cortese, G Estiu, K Galinsky, V Zuzarte-Luis, ... Science Translational Medicine 7 (288), 288ra77-288ra77, 2015 | 100 | 2015 |
| AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis H Xu, Q Zhao, N Song, Z Yan, R Lin, S Wu, L Jiang, S Hong, J Xie, H Zhou, ... Nature communications 11 (1), 5807, 2020 | 81 | 2020 |
| DeepChemStable: Chemical Stability Prediction with an Attention-based Graph Convolution Network X Li, X Yan, Q Gu, H Zhou, D Wu, J Xu Journal of Chemical Information and Modeling 59, 1044-1049, 2019 | 67 | 2019 |
| Synthesis and evaluation of tetrahydroisoquinoline-benzimidazole hybrids as multifunctional agents for the treatment of Alzheimer's disease Y Fang, H Zhou, Q Gu, J Xu European Journal of Medicinal Chemistry 167, 133-145, 2019 | 55 | 2019 |
| Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid Y Song, H Zhou, MN Vo, Y Shi, MH Nawaz, O Vargas-Rodriguez, ... Nature Communications 8 (1), 2281, 2017 | 44 | 2017 |
| Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4: U69 Base Pair L Sun, AC Gomes, W He, H Zhou, X Wang, DW Pan, P Schimmel, T Pan, ... Journal of the American Chemical Society 138 (39), 12948-12955, 2016 | 42 | 2016 |
| Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21 H Zhou, Z Zha, Y Liu, H Zhang, J Zhu, S Hu, G Shen, L Cheng, L Niu, ... Journal of Biological Chemistry 286 (36), 31676-31683, 2011 | 40 | 2011 |
| Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris Y Ju, S Tong, Y Gao, W Zhao, Q Liu, Q Gu, J Xu, L Niu, M Teng, H Zhou Journal of Structural Biology 195 (3), 306-315, 2016 | 35 | 2016 |
| Discovery of a New Pterocarpan-Type Antineuroinflammatory Compound from Sophora tonkinensis through Suppression of the TLR4/NFκB/MAPK Signaling … W Xia, P Luo, P Hua, P Ding, C Li, J Xu, H Zhou, Q Gu ACS chemical neuroscience 10 (1), 295-303, 2018 | 34 | 2018 |
| Design, synthesis, and biological evaluation of compounds with a new scaffold as anti-neuroinflammatory agents for the treatment of Alzheimer's disease. Y Fang, W Xia, B Cheng, P Hua, H Zhou, Q Gu, J Xu European journal of medicinal chemistry 149, 129-138, 2018 | 30 | 2018 |
| TCMAnalyzer: A Chemo-and Bioinformatics Web Service for Analyzing Traditional Chinese Medicine Z Liu, J Du, X Yan, J Zhong, L Cui, J Lin, L Zeng, P Ding, P Chen, X Zhou, ... Journal of chemical information and modeling 58 (3), 550-555, 2018 | 29 | 2018 |
| cBinderDB: a covalent binding agent database J Du, X Yan, Z Liu, L Cui, P Ding, X Tan, X Li, H Zhou, Q Gu, J Xu Bioinformatics 33 (8), 1258-1260, 2017 | 27 | 2017 |
| Oridonin inhibits SARS‐CoV‐2 by targeting its 3C‐Like protease B Zhong, W Peng, S Du, B Chen, Y Feng, X Hu, Q Lai, S Liu, ZW Zhou, ... Small science 2 (6), 2100124, 2022 | 26 | 2022 |
| Systematic Studies on the Protocol and Criteria for Selecting a Covalent Docking Tool C Wen, X Yan, Q Gu, J Du, D Wu, Y Lu, H Zhou, J Xu Molecules 24 (11), 2183, 2019 | 26 | 2019 |
| Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors Z Chen, H Chen, Z Zhang, P Ding, X Yan, Y Li, S Zhang, Q Gu, H Zhou, ... European Journal of Medicinal Chemistry 206, 112793, 2020 | 21 | 2020 |
| Discovery of phloroglucinols from Hypericum japonicum as ferroptosis inhibitors X Peng, Q Tan, H Zhou, J Xu, Q Gu Fitoterapia 153, 104984, 2021 | 20 | 2021 |
Qiong GuSchool of Pharmaceutical Sciences, Sun Yat-Sen UniversityGeverifieerd e-mailadres voor mail.sysu.edu.cn
