A deliberate approach to screening for initial crystallization conditions of biological macromolecules JR Luft, RJ Collins, NA Fehrman, AM Lauricella, CK Veatch, GT DeTitta Journal of structural biology 142 (1), 170-179, 2003 | 329 | 2003 |
Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis N Galitsky, V Cody, A Wojtczak, D Ghosh, JR Luft, W Pangborn, L English Acta Crystallographica Section D: Biological Crystallography 57 (8), 1101-1109, 2001 | 240 | 2001 |
Device for growing crystals GT Detitta, JR Luft US Patent 5,400,741, 1995 | 202 | 1995 |
Structures of human transthyretin complexed with thyroxine at 2.0 Ć resolution and 3', 5'-dinitro-N-acetyl-L-thyronine at 2.2 Ć resolution A Wojtczak, V Cody, JR Luft, W Pangborn Acta Crystallographica Section D: Biological Crystallography 52 (4), 758-765, 1996 | 194 | 1996 |
Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data WN Price Ii, Y Chen, SK Handelman, H Neely, P Manor, R Karlin, R Nair, ... Nature biotechnology 27 (1), 51-57, 2009 | 168 | 2009 |
A method to produce microseed stock for use in the crystallization of biological macromolecules JR Luft, GT DeTitta Acta Crystallographica Section D: Biological Crystallography 55 (5), 988-993, 1999 | 144 | 1999 |
Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22: kinetics, crystallography, and potential as selectable markers WS Lewis, V Cody, N Galitsky, JR Luft, W Pangborn, SK Chunduru, ... Journal of Biological Chemistry 270 (10), 5057-5064, 1995 | 135 | 1995 |
Macromolecular crystallization in a high throughput laboratory—the search phase JR Luft, J Wolfley, I Jurisica, J Glasgow, S Fortier, GT DeTitta Journal of Crystal Growth 232 (1-4), 591-595, 2001 | 125 | 2001 |
Mechanism of molecular recognition. Structural aspects of 3, 3'-diiodo-L-thyronine binding to human serum transthyretin. A Wojtczak, J Luft, V Cody Journal of Biological Chemistry 267 (1), 353-357, 1992 | 97 | 1992 |
Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal … V Cody, JR Luft, W Pangborn Acta Crystallographica D Biological Crystallography 61 (2), 147-55, 2005 | 93 | 2005 |
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies TL Arakaki, FS Buckner, JR Gillespie, NA Malmquist, MA Phillips, ... Molecular microbiology 68 (1), 37-50, 2008 | 81 | 2008 |
Ligand-Induced Conformational Changes in the Crystal Structures of Pneumocystis carinii Dihydrofolate Reductase Complexes with Folate and NADP+ , V Cody, N Galitsky, D Rak, JR Luft, W Pangborn, SF Queener Biochemistry 38 (14), 4303-4312, 1999 | 81 | 1999 |
Method for screening microcrystallizations for crystal formation BD Santarsiero, RC Stevens, PG Schultz, JM Jaklevic, DT Yegian, ... US Patent 6,630,006, 2003 | 80 | 2003 |
Automatic classification of sub-microlitre protein-crystallization trials in 1536-well plates CA Cumbaa, A Lauricella, N Fehrman, C Veatch, R Collins, JR Luft, ... Acta Crystallographica Section D: Biological Crystallography 59 (9), 1619-1627, 2003 | 77 | 2003 |
Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor … PW Gangjee A, Vidwans AP, Vasudevan A, Queener SF, Kisliuk RL, Cody V, Li R ... Journal of Medicinal Chemistry 41 (18), 3426-34, 1998 | 76 | 1998 |
Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 Ć resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two … A Wojtczak, V Cody, JR Luft, W Pangborn Acta Crystallographica Section D: Biological Crystallography 57 (8), 1061-1070, 2001 | 74 | 2001 |
Intelligent decision support for protein crystal growth I Jurisica, P Rogers, JI Glasgow, S Fortier, JR Luft, JR Wolfley, MA Bianca, ... IBM Systems Journal 40 (2), 394-409, 2001 | 74 | 2001 |
[7] Kinetic aspects of macromolecular crystallization JR Luft, GT Detitta Methods in enzymology 276, 110-131, 1997 | 74 | 1997 |
Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase J Bosch, MA Robien, C Mehlin, E Boni, A Riechers, FS Buckner, ... Journal of medicinal chemistry 49 (20), 5939-5946, 2006 | 72 | 2006 |
Crystallization screening: the influence of history on current practice JR Luft, J Newman, EH Snell Acta Crystallographica Section F 70 (7), 835-853, 2014 | 70 | 2014 |