| Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities M Cnop, N Welsh, JC Jonas, A Jorns, S Lenzen, DL Eizirik Diabetes 54 (suppl_2), S97-S107, 2005 | 1946 | 2005 |
| The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells DL Eizirik, M Flodström, AE Karlsen, N Welsh Diabetologia 39, 875-890, 1996 | 430 | 1996 |
| Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme … N Welsh, DL Eizirik, K BENDTZEN, S SANDLER Endocrinology 129 (6), 3167-3173, 1991 | 410 | 1991 |
| Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. DL Eizirik, S Sandler, N Welsh, M Cetkovic-Cvrlje, A Nieman, DA Geller, ... The Journal of clinical investigation 93 (5), 1968-1974, 1994 | 388 | 1994 |
| Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. DL Eizirik, DG Pipeleers, Z Ling, N Welsh, C Hellerström, A Andersson Proceedings of the National Academy of Sciences 91 (20), 9253-9256, 1994 | 348 | 1994 |
| Sodium Palmitate Induces Partial Mitochondrial Uncoupling and Reactive Oxygen Species in Rat Pancreatic Islets in Vitro C Carlsson, LA Hakan Borg, N Welsh Endocrinology 140 (8), 3422-3428, 1999 | 309 | 1999 |
| Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent … N Welsh, B Margulis, LAH Borg, HJ Wiklund, J Saldeen, M Flodström, ... Molecular medicine 1, 806-820, 1995 | 261 | 1995 |
| Control of insulin mRNA stability in rat pancreatic islets: regulatory role of a 3′-untranslated region pyrimidine-rich sequence L Tillmar, C Carlsson, N Welsh Journal of Biological Chemistry 277 (2), 1099-1106, 2002 | 200 | 2002 |
| Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Δψm) in pancreatic RINm5F cells: prevention by Bcl-2 A Barbu, N Welsh, J Saldeen Molecular and cellular endocrinology 190 (1-2), 75-82, 2002 | 156 | 2002 |
| Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets? N Welsh, M Cnop, I Kharroubi, M Bugliani, R Lupi, P Marchetti, DL Eizirik Diabetes 54 (11), 3238-3244, 2005 | 155 | 2005 |
| Detailed transcriptome atlas of the pancreatic beta cell B Kutlu, D Burdick, D Baxter, J Rasschaert, D Flamez, DL Eizirik, N Welsh, ... BMC medical genomics 2, 1-11, 2009 | 153 | 2009 |
| Amelioration of diabetes by imatinib mesylate (Gleevec®): role of‐cell NF‐KB activation and anti‐apoptotic preconditioning R Hägerkvist, S Sandler, D Mokhtari, N Welsh The FASEB Journal 21 (2), 618-628, 2007 | 151 | 2007 |
| Developmental damage, increased lipid peroxidation, diminished cyclooxygenase-2 gene expression, and lowered prostaglandin E2 levels in rat embryos exposed to a diabetic … P Wentzel, N Welsh, UJ Eriksson Diabetes 48 (4), 813-820, 1999 | 150 | 1999 |
| Cytokines activate the nuclear factor κB (NF-κB) and induce nitric oxide production in human pancreatic islets M Flodströma, N Welsh, DL Eizirik FEBS letters 385 (1-2), 4-6, 1996 | 146 | 1996 |
| C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells F Allagnat, M Fukaya, TC Nogueira, D Delaroche, N Welsh, L Marselli, ... Cell Death & Differentiation 19 (11), 1836-1846, 2012 | 145 | 2012 |
| Interleukin-1β-induced Ceramide and Diacylglycerol Generation 5 Lead to Activation of the c-Jun NH2-terminal Kinase and the Transcription Factor ATF2 in the Insulin-producing … N Welsh Journal of biological chemistry 271 (14), 8307-8312, 1996 | 141 | 1996 |
| Biochemical and molecular actions of interleukin-1 on pancreatic β-cells S Sandler, DL Eizirik, C Svensson, E Strandell, M Welsh, N Welsh Autoimmunity 10 (3), 241-253, 1991 | 137 | 1991 |
| Interleukin-1β induces the expression of an isoform of nitric oxide synthase in insulin-producing cells, which is similar to that observed in activated macrophages DL Eizirik, E Cagliero, A Björklund, N Welsh FEBS letters 308 (3), 249-252, 1992 | 135 | 1992 |
| Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels. P Rorsman, P Arkhammar, K Bokvist, C Hellerström, T Nilsson, M Welsh, ... Proceedings of the National Academy of Sciences 86 (12), 4505-4509, 1989 | 127 | 1989 |
| Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis J Saldeen, JC Lee, N Welsh Biochemical pharmacology 61 (12), 1561-1569, 2001 | 125 | 2001 |
