Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement D Ugurlar, SC Howes, BJ de Kreuk, RI Koning, RN de Jong, FJ Beurskens, ... Science 359 (6377), 794-797, 2018 | 155 | 2018 |
The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration BJ de Kreuk, M Nethe, M Fernandez-Borja, EC Anthony, PJ Hensbergen, ... Journal of cell science 124 (14), 2375-2388, 2011 | 108 | 2011 |
Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations MA Lopez-Ramirez, G Fonseca, HA Zeineddine, R Girard, T Moore, ... Journal of Experimental Medicine 214 (11), 3331-3346, 2017 | 94 | 2017 |
Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody S Gulati, FJ Beurskens, BJ de Kreuk, M Roza, B Zheng, RB DeOliveira, ... PLoS Biology 17 (6), e3000323, 2019 | 69 | 2019 |
Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity BJ de Kreuk, AR Gingras, JDR Knight, JJ Liu, AC Gingras, MH Ginsberg Elife 5, e11394, 2016 | 53 | 2016 |
The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization BJ de Kreuk, EC Anthony, D Geerts, PL Hordijk Journal of Biological Chemistry 287 (52), 43438-43453, 2012 | 43 | 2012 |
The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions YL Dorland, TS Malinova, AMD Van Stalborch, AG Grieve, ... Nature communications 7 (1), 12210, 2016 | 42 | 2016 |
The human minor histocompatibility antigen1 is a RhoGAP BJ de Kreuk, A Schaefer, EC Anthony, S Tol, M Fernandez-Borja, ... PloS one 8 (9), e73962, 2013 | 42 | 2013 |
Control of Rho GTPase function by BAR-domains BJ de Kreuk, PL Hordijk Small GTPases 3 (1), 45-52, 2012 | 36 | 2012 |
Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell–cell contacts M Nethe, BJ de Kreuk, DVF Tauriello, EC Anthony, B Snoek, T Stumpel, ... Journal of cell science 125 (14), 3430-3442, 2012 | 31 | 2012 |
Carbamylation reduces the capacity of IgG for hexamerization and complement activation R Lubbers, SC Oostindie, DJ Dijkstra, PWHI Parren, MK Verheul, ... Clinical & Experimental Immunology 200 (1), 1-11, 2020 | 12 | 2020 |
Antibody variant combinations and uses thereof R De Jong, F Beurskens, S Oostindie, AF Labrijn, K Strumane, ... US Patent App. 17/051,205, 2021 | | 2021 |
Complement alone drives efficacy of a chimeric anti-gonococcal monoclonal antibody F Beurskens, BJ de Kreuk, M Roza, B Zheng, R DeOliveira, ... Molecular Immunology 114, 411-412, 2019 | | 2019 |
Potentiation of efficacy of a candidate immunotherapeutic antibody to Neisseria gonorrhoeae by enhancing IgG Fc hexamer formation S Gulati, FJ Beurskens, BJ de Kreuk, M Roza, B Zheng, RP Taylor, ... Molecular Immunology 102, 157, 2018 | | 2018 |
THE F-BAR PROTEIN PACSIN2 REGULATES GROWTH FACTOR RECEPTOR ACTIVATION AND SIGNALING BJ de Kreuk, EC Anthony, D Geerts, PL Hordijk Signaling behind bars: a role for bar domains, 106, 0 | | |