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Bart-Jan de Kreuk
Bart-Jan de Kreuk
Scientist ART, Genmab B.V. Utrecht, the Netherlands
Geverifieerd e-mailadres voor genmab.com
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Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement
D Ugurlar, SC Howes, BJ de Kreuk, RI Koning, RN de Jong, FJ Beurskens, ...
Science 359 (6377), 794-797, 2018
1542018
The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration
BJ de Kreuk, M Nethe, M Fernandez-Borja, EC Anthony, PJ Hensbergen, ...
Journal of cell science 124 (14), 2375-2388, 2011
1072011
Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations
MA Lopez-Ramirez, G Fonseca, HA Zeineddine, R Girard, T Moore, ...
Journal of Experimental Medicine 214 (11), 3331-3346, 2017
932017
Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody
S Gulati, FJ Beurskens, BJ de Kreuk, M Roza, B Zheng, RB DeOliveira, ...
PLoS Biology 17 (6), e3000323, 2019
682019
Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity
BJ de Kreuk, AR Gingras, JDR Knight, JJ Liu, AC Gingras, MH Ginsberg
Elife 5, e11394, 2016
532016
The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization
BJ de Kreuk, EC Anthony, D Geerts, PL Hordijk
Journal of Biological Chemistry 287 (52), 43438-43453, 2012
432012
The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions
YL Dorland, TS Malinova, AMD Van Stalborch, AG Grieve, ...
Nature communications 7 (1), 12210, 2016
412016
The human minor histocompatibility antigen1 is a RhoGAP
BJ de Kreuk, A Schaefer, EC Anthony, S Tol, M Fernandez-Borja, ...
PloS one 8 (9), e73962, 2013
412013
Control of Rho GTPase function by BAR-domains
BJ de Kreuk, PL Hordijk
Small GTPases 3 (1), 45-52, 2012
362012
Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell–cell contacts
M Nethe, BJ de Kreuk, DVF Tauriello, EC Anthony, B Snoek, T Stumpel, ...
Journal of cell science 125 (14), 3430-3442, 2012
312012
Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell–cell contacts
M Nethe, BJ de Kreuk, DVF Tauriello, EC Anthony, B Snoek, T Stumpel, ...
Journal of cell science 125 (14), 3430-3442, 2012
312012
Carbamylation reduces the capacity of IgG for hexamerization and complement activation
R Lubbers, SC Oostindie, DJ Dijkstra, PWHI Parren, MK Verheul, ...
Clinical & Experimental Immunology 200 (1), 1-11, 2020
112020
Antibody variant combinations and uses thereof
R De Jong, F Beurskens, S Oostindie, AF Labrijn, K Strumane, ...
US Patent App. 17/051,205, 2021
2021
Complement alone drives efficacy of a chimeric anti-gonococcal monoclonal antibody
F Beurskens, BJ de Kreuk, M Roza, B Zheng, R DeOliveira, ...
Molecular Immunology 114, 411-412, 2019
2019
Potentiation of efficacy of a candidate immunotherapeutic antibody to Neisseria gonorrhoeae by enhancing IgG Fc hexamer formation
S Gulati, FJ Beurskens, BJ de Kreuk, M Roza, B Zheng, RP Taylor, ...
Molecular Immunology 102, 157, 2018
2018
THE F-BAR PROTEIN PACSIN2 REGULATES GROWTH FACTOR RECEPTOR ACTIVATION AND SIGNALING
BJ de Kreuk, EC Anthony, D Geerts, PL Hordijk
Signaling behind bars: a role for bar domains, 106, 0
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Artikelen 1–16