| Accurate detection of m6A RNA modifications in native RNA sequences H Liu, O Begik, MC Lucas, JM Ramirez, CE Mason, D Wiener, S Schwartz, ... Nature communications 10 (1), 4079, 2019 | 431 | 2019 |
| Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 257 | 2017 |
| CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019 | 231 | 2019 |
| Quantitative profiling of pseudouridylation dynamics in native RNAs with nanopore sequencing O Begik, MC Lucas, LP Pryszcz, JM Ramirez, R Medina, I Milenkovic, ... Nature biotechnology 39 (10), 1278-1291, 2021 | 227 | 2021 |
| Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer J Chang, MC Lucas, LE Leonte, M Garcia-Montolio, LB Singh, AD Findlay, ... Oncotarget 8 (16), 26066, 2017 | 125 | 2017 |
| Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis M Samuel, P Fonseka, R Sanwlani, L Gangoda, SH Chee, ... Nature Communications 12 (1), 3950, 2021 | 115 | 2021 |
| Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ... Nature communications 13 (1), 4587, 2022 | 114 | 2022 |
| Recent advances in understanding the complexities of metastasis JL Chitty, EC Filipe, MC Lucas, D Herrmann, TR Cox, P Timpson F1000Research 7, 2018 | 101 | 2018 |
| Recent advances in understanding the complexities of metastasis JL Chitty, EC Filipe, MC Lucas, D Herrmann, TR Cox, P Timpson F1000Research 7, 2018 | 101 | 2018 |
| A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ... Cell reports 21 (1), 274-288, 2017 | 96 | 2017 |
| Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing MC Lucas, LP Pryszcz, R Medina, I Milenkovic, N Camacho, V Marchand, ... Nature Biotechnology 42 (1), 72-86, 2024 | 93 | 2024 |
| SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer NLE Harris, C Vennin, JRW Conway, KL Vine, M Pinese, MJ Cowley, ... Oncogene 36 (30), 4288-4298, 2017 | 91 | 2017 |
| MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib AIJ Young, AMK Law, L Castillo, S Chong, HD Cullen, M Koehler, ... Breast Cancer Research 18, 1-15, 2016 | 88 | 2016 |
| Integrative analyses of the RNA modification machinery reveal tissue-and cancer-specific signatures O Begik, MC Lucas, H Liu, JM Ramirez, JS Mattick, EM Novoa Genome biology 21, 1-24, 2020 | 74 | 2020 |
| Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease-and drug-dependent dynamic regulation of cell-cell junctions in live tissue Z Erami, D Herrmann, SC Warren, M Nobis, EJ McGhee, MC Lucas, ... Cell reports 14 (1), 152-167, 2016 | 71 | 2016 |
| Molecular barcoding of native RNAs using nanopore sequencing and deep learning MA Smith, T Ersavas, JM Ferguson, H Liu, MC Lucas, O Begik, L Bojarski, ... Genome research 30 (9), 1345-1353, 2020 | 67 | 2020 |
| Long-read sequencing in the era of epigenomics and epitranscriptomics MC Lucas, EM Novoa Nature Methods 20 (1), 25-29, 2023 | 52 | 2023 |
| Molecular mobility and activity in an intravital imaging setting–implications for cancer progression and targeting M Nobis, SC Warren, MC Lucas, KJ Murphy, D Herrmann, P Timpson Journal of Cell Science 131 (5), jcs206995, 2018 | 36 | 2018 |
| Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status KJ Murphy, DA Reed, C Vennin, JRW Conway, M Nobis, JX Yin, ... Science advances 7 (40), eabh0363, 2021 | 33 | 2021 |
| A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer JL Chitty, M Yam, L Perryman, AL Parker, JN Skhinas, YFI Setargew, ... Nature Cancer 4 (9), 1326-1344, 2023 | 31 | 2023 |
Eva Maria NovoaICREA Professor & Group LeaderVerified email at crg.eu
