The Effect of Hyperglycaemia on In Vitro Cytokine Production and Macrophage Infection with Mycobacterium tuberculosis E Lachmandas, F Vrieling, LG Wilson, SA Joosten, MG Netea, ... PloS one 10 (2), e0117941, 2015 | 60 | 2015 |
Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages XAMH van Dierendonck, F Vrieling, L Smeehuijzen, L Deng, JP Boogaard, ... Proceedings of the National Academy of Sciences 119 (12), e2114739119, 2022 | 53 | 2022 |
Patients with concurrent tuberculosis and diabetes have a pro-atherogenic plasma lipid profile F Vrieling, K Ronacher, L Kleynhans, E Van Den Akker, G Walzl, ... EBioMedicine 32, 192-200, 2018 | 50 | 2018 |
Plasma metabolomics in tuberculosis patients with and without concurrent type 2 diabetes at diagnosis and during antibiotic treatment F Vrieling, B Alisjahbana, E Sahiratmadja, R van Crevel, AC Harms, ... Scientific reports 9 (1), 18669, 2019 | 47 | 2019 |
Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction F Vrieling, L Wilson, PCN Rensen, G Walzl, THM Ottenhoff, SA Joosten PLoS pathogens 15 (4), e1007724, 2019 | 45 | 2019 |
Functional Inhibition of Host Histone Deacetylases (HDACs) Enhances in vitro and in vivo Anti-mycobacterial Activity in Human Macrophages and in Zebrafish JD Moreira, BEV Koch, S van Veen, KV Walburg, F Vrieling, ... Frontiers in immunology 11, 36, 2020 | 42 | 2020 |
Analyzing the impact of Mycobacterium tuberculosis infection on primary human macrophages by combined exploratory and targeted metabolomics F Vrieling, S Kostidis, HP Spaink, MC Haks, OA Mayboroda, ... Scientific reports 10 (1), 7085, 2020 | 35 | 2020 |
BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice AD van Dam, S Bekkering, M Crasborn, L van Beek, SM van den Berg, ... Atherosclerosis 251, 6-14, 2016 | 25 | 2016 |
Obesity and dysregulated innate immune responses: impact of micronutrient deficiencies F Vrieling, R Stienstra Trends in Immunology 44 (3), 217-230, 2023 | 14 | 2023 |
The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory in vitro human intestinal model B van der Lugt, MCP Vos, MG Bromhaar, N Ijssennagger, F Vrieling, ... Heliyon 8 (2), 2022 | 12 | 2022 |
Macrophages take up VLDL-sized emulsion particles through caveolae-mediated endocytosis and excrete part of the internalized triglycerides as fatty acids L Deng, F Vrieling, R Stienstra, GJ Hooiveld, AL Feitsma, S Kersten PLoS Biology 20 (8), e3001516, 2022 | 10 | 2022 |
Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections MT Heemskerk, CJ Korbee, J Esselink, CC dos Santos, S van Veen, ... Scientific Reports, 2021 | 9 | 2021 |
An internet-based psychological intervention with a serious game to improve vitality, psychological and physical condition, and immune function in healthy male adults … L Schakel, DS Veldhuijzen, H van Middendorp, C Prins, AMHF Drittij, ... Journal of Medical Internet Research 22 (7), e14861, 2020 | 9 | 2020 |
Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate Improves Host Control of Salmonella enterica Serovar Typhimurium Infection in Human Macrophages CLR van Doorn, GK Schouten, S van Veen, KV Walburg, JJ Esselink, ... Frontiers in Immunology 12, 739938, 2021 | 7 | 2021 |
Metabolic heterogeneity of tissue-resident macrophages in homeostasis and during helminth infection GA Heieis, TA Patente, L Almeida, F Vrieling, T Tak, G Perona-Wright, ... Nature Communications 14 (1), 5627, 2023 | 6 | 2023 |
In-depth immunometabolic profiling by measuring single-cell protein translation inhibition via bioorthogonal noncanonical amino acid tagging (SCENITH-BONCAT) F Vrieling, HJP van der Zande, L Smeehuijzen, J van den Bossche, ... bioRxiv, 2023.08. 03.551800, 2023 | 2 | 2023 |
Glycolytic activity in human immune cells: inter-individual variation and functional implications during health and diabetes F Vrieling, XAMH van Dierendonck, M Jaeger, AWM Janssen, A Hijmans, ... Immunometabolism 4 (4), e00008, 2022 | 2 | 2022 |
Immunometabolic Signatures of Circulating Monocytes in Humans with Obesity and Insulin Resistance L Smeehuijzen, A Gijbels, JP Nugteren-Boogaard, F Vrieling, ... Diabetes, db230970, 2024 | | 2024 |
Milk fat globule membrane modulates inflammatory pathways in human monocytes: A crossover human intervention study L Deng, CCJR Michielsen, F Vrieling, GJEJ Hooiveld, R Stienstra, ... Clinical Nutrition 43 (1), 232-245, 2024 | | 2024 |
Are postprandial glucose responses sufficiently person-specific to use in personalized dietary advice? Design of the RepEAT study: a fully controlled dietary intervention to … M Daanje, E Siebelink, F Vrieling, M van den Belt, S van der Haar, ... Frontiers in Nutrition 10, 2023 | | 2023 |