| Heart disease and stroke statistics 2005 update American Heart Association http://www. americanheart. org/statistics/, 2005 | 8549* | 2005 |
| Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128· 9 million … L Abarca-Gómez, ZA Abdeen, ZA Hamid, NM Abu-Rmeileh, ... The lancet 390 (10113), 2627-2642, 2017 | 7767 | 2017 |
| Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19· 2 million participants NCD Risk Factor Collaboration Lancet (London, England) 387 (10026), 1377, 2016 | 5561 | 2016 |
| Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis L Bellamy, JP Casas, AD Hingorani, D Williams The Lancet 373 (9677), 1773-1779, 2009 | 4105 | 2009 |
| Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4· 4 million participants B Zhou, Y Lu, K Hajifathalian, J Bentham, M Di Cesare, G Danaei, H Bixby, ... The lancet 387 (10027), 1513-1530, 2016 | 4103 | 2016 |
| Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis L Bellamy, JP Casas, AD Hingorani, DJ Williams Bmj 335 (7627), 974, 2007 | 3082 | 2007 |
| Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 (7359), 214-219, 2011 | 2954 | 2011 |
| Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19· 1 million participants B Zhou, J Bentham, M Di Cesare, H Bixby, G Danaei, MJ Cowan, ... The Lancet 389 (10064), 37-55, 2017 | 2677 | 2017 |
| Statins for the primary prevention of cardiovascular disease F Taylor, K Ward, THM Moore, M Burke, GD Smith, JP Casas, S Ebrahim Cochrane database of systematic reviews, 2011 | 2659 | 2011 |
| Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ... Nature 478 (7367), 103-109, 2011 | 2283 | 2011 |
| The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium The Lancet 379 (9822), 1214-1224, 2012 | 1055 | 2012 |
| Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ... Nature genetics 44 (12), 1341-1348, 2012 | 1050 | 2012 |
| Genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1 A Strange, F Capon, CCA Spencer, J Knight, ME Weale, MH Allen, ... Nature genetics 42 (11), 985, 2010 | 1017 | 2010 |
| Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis JP Casas, W Chua, S Loukogeorgakis, P Vallance, L Smeeth, ... The lancet 366 (9502), 2026-2033, 2005 | 978 | 2005 |
| Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility Australo-Anglo-American Spondyloarthritis Consortium (TASC), ... Nature genetics 43 (8), 761-767, 2011 | 955 | 2011 |
| Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 839 | 2019 |
| World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions S Kaptoge, L Pennells, D De Bacquer, MT Cooney, M Kavousi, G Stevens, ... The Lancet global health 7 (10), e1332-e1345, 2019 | 804 | 2019 |
| Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data MV Holmes, CE Dale, L Zuccolo, RJ Silverwood, Y Guo, Z Ye, ... Bmj 349, g4164, 2014 | 802 | 2014 |
| Mendelian randomization of blood lipids for coronary heart disease MV Holmes, FW Asselbergs, TM Palmer, F Drenos, MB Lanktree, ... European heart journal 36 (9), 539-550, 2015 | 758 | 2015 |
| Rising rural body-mass index is the main driver of the global obesity epidemic in adults Nature 569 (7755), 260-264, 2019 | 714 | 2019 |
