| Single-cell transcriptomic analysis of primary and metastatic tumor ecosystems in head and neck cancer SV Puram, I Tirosh, AS Parikh, AP Patel, K Yizhak, S Gillespie, C Rodman, ... Cell 171 (7), 1611-1624. e24, 2017 | 2018 | 2017 |
| B cells and tertiary lymphoid structures promote immunotherapy response BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ... Nature 577 (7791), 549-555, 2020 | 1869 | 2020 |
| Defining T cell states associated with response to checkpoint immunotherapy in melanoma M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ... Cell 175 (4), 998-1013. e20, 2018 | 1524 | 2018 |
| Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ... Nature 539 (7628), 309-313, 2016 | 1056 | 2016 |
| Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ... Science 355 (6332), eaai8478, 2017 | 895 | 2017 |
| Resistance to checkpoint blockade therapy through inactivation of antigen presentation M Sade-Feldman, YJ Jiao, JH Chen, MS Rooney, M Barzily-Rokni, ... Nature communications 8 (1), 1136, 2017 | 850 | 2017 |
| Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ... Science 360 (6386), 331-335, 2018 | 587 | 2018 |
| RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues K Yizhak, F Aguet, J Kim, JM Hess, K Kübler, J Grimsby, R Frazer, ... Science 364 (6444), eaaw0726, 2019 | 465 | 2019 |
| Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis S Rabinovich, L Adler, K Yizhak, A Sarver, A Silberman, S Agron, ... Nature 527 (7578), 379-383, 2015 | 347 | 2015 |
| Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model K Yizhak, T Benyamini, W Liebermeister, E Ruppin, T Shlomi Bioinformatics 26 (12), i255-i260, 2010 | 310 | 2010 |
| PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance V Verma, RK Shrimali, S Ahmad, W Dai, H Wang, S Lu, R Nandre, P Gaur, ... Nature immunology 20 (9), 1231-1243, 2019 | 276 | 2019 |
| Defining T cell states associated with response to checkpoint immunotherapy in melanoma M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ... Cell 176 (1), 404, 2019 | 220 | 2019 |
| Modeling cancer metabolism on a genome scale K Yizhak, B Chaneton, E Gottlieb, E Ruppin Molecular systems biology 11 (6), 817, 2015 | 185 | 2015 |
| A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration K Yizhak, SE Le Dévédec, VM Rogkoti, F Baenke, VC De Boer, C Frezza, ... Molecular systems biology 10 (8), 744, 2014 | 168 | 2014 |
| Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer K Yizhak, E Gaude, S Le Dévédec, YY Waldman, GY Stein, ... Elife 3, e03641, 2014 | 147 | 2014 |
| Model-based identification of drug targets that revert disrupted metabolism and its application to ageing K Yizhak, O Gabay, H Cohen, E Ruppin Nature communications 4, 2632, 2013 | 108 | 2013 |
| p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production I Goldstein, K Yizhak, S Madar, N Goldfinger, E Ruppin, V Rotter Cancer & metabolism 1, 1-6, 2013 | 87 | 2013 |
| Integrating transcriptomics with metabolic modeling predicts biomarkers and drug targets for Alzheimer's disease S Stempler, K Yizhak, E Ruppin PloS one 9 (8), e105383, 2014 | 67 | 2014 |
| Targeting TBK1 to overcome resistance to cancer immunotherapy Y Sun, O Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, ... Nature 615 (7950), 158-167, 2023 | 65 | 2023 |
| A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer N Auslander, K Yizhak, A Weinstock, A Budhu, W Tang, XW Wang, ... Scientific reports 6 (1), 29662, 2016 | 55 | 2016 |
Eytan RuppinChief, Cancer Data Science Lab (CDSL), NCI/NIHVerified email at nih.gov
