Defective HIV-1 proviruses are expressed and can be recognized by cytotoxic T lymphocytes, which shape the proviral landscape RA Pollack, RB Jones, M Pertea, KM Bruner, AR Martin, AS Thomas, ... Cell host & microbe 21 (4), 494-506. e4, 2017 | 342 | 2017 |
Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells SH Huang, Y Ren, AS Thomas, D Chan, S Mueller, AR Ward, S Patel, ... The Journal of clinical investigation 128 (2), 876-889, 2018 | 188 | 2018 |
A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes RB Jones, S Mueller, R O’Connor, K Rimpel, DD Sloan, D Karel, ... PLoS pathogens 12 (4), e1005545, 2016 | 178 | 2016 |
BCL-2 antagonism sensitizes cytotoxic T cell–resistant HIV reservoirs to elimination ex vivo Y Ren, SH Huang, S Patel, WDC Alberto, D Magat, D Ahimovic, ... The Journal of Clinical Investigation 130 (5), 2542-2559, 2020 | 91 | 2020 |
Dual TLR2 and TLR7 agonists as HIV latency-reversing agents AB Macedo, CL Novis, CM De Assis, ES Sorensen, P Moszczynski, ... JCI insight 3 (19), 2018 | 77 | 2018 |
HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA) NN Kinloch, Y Ren, WD Conce Alberto, W Dong, P Khadka, SH Huang, ... Nature communications 12 (1), 1-10, 2021 | 71 | 2021 |
Evidence that CD32a does not mark the HIV-1 latent reservoir CE Osuna, SY Lim, JL Kublin, R Apps, E Chen, TM Mota, SH Huang, ... Nature 561 (7723), E20-E28, 2018 | 66 | 2018 |
Evidence that CD32a does not mark the HIV-1 latent reservoir CE Osuna, SY Lim, JL Kublin, R Apps, E Chen, TM Mota, SH Huang, ... Nature 561 (7723), E20-E28, 2018 | 64 | 2018 |
Evidence that CD32a does not mark the HIV-1 latent reservoir CE Osuna, SY Lim, JL Kublin, R Apps, E Chen, TM Mota, SH Huang, ... Nature 561 (7723), E20-E28, 2018 | 64 | 2018 |
T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy AS Thomas, KL Jones, RT Gandhi, DK McMahon, JC Cyktor, D Chan, ... PLoS pathogens 13 (9), e1006629, 2017 | 47 | 2017 |
T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy AS Thomas, KL Jones, RT Gandhi, DK McMahon, JC Cyktor, D Chan, ... PLoS pathogens 13 (9), e1006629, 2017 | 47 | 2017 |
HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy EM Stevenson, AR Ward, R Truong, AS Thomas, SH Huang, TR Dilling, ... JCI insight 6 (3), 2021 | 39 | 2021 |
Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs Y Ren, M Korom, R Truong, D Chan, SH Huang, CC Kovacs, E Benko, ... Journal of Virology, JVI. 00895-18, 2018 | 28 | 2018 |
Integrated Assessment of Viral Transcription, Antigen Presentation, and CD8+ T Cell Function Reveals Multiple Limitations of Class I-Selective Histone … TM Mota, CD McCann, A Danesh, SH Huang, DB Magat, Y Ren, L Leyre, ... Journal of virology 94 (9), e01845-19, 2020 | 21 | 2020 |
Have Cells Harboring the HIV Reservoir Been Immunoedited? SH Huang, C McCann, T Mota, RB Jones Frontiers in Immunology 10, 1842, 2019 | 16 | 2019 |
IFITM1 targets HIV-1 latently infected cells for antibody-dependent cytolysis RAS Raposo, M de Mulder Rougvie, D Paquin-Proulx, PM Brailey, ... JCI insight 2 (1), 2017 | 16 | 2017 |
The Intact Noninducible Latent HIV-1 Reservoir Is Established in an In Vitro Primary TCM Cell Model of Latency I Sarabia, SH Huang, AR Ward, RB Jones, A Bosque Journal of Virology 95 (7), e01297-20, 2021 | 13 | 2021 |
Increased expression of the integral membrane proteins EGFR and FGFR3 in anti‐apoptotic Chinese hamster ovary cell lines E Ohsfeldt, SH Huang, D Baycin‐Hizal, L Kristoffersen, TMT Le, E Li, ... Biotechnology and applied biochemistry 59 (3), 155-162, 2012 | 12 | 2012 |
Relationships between neutralization, binding, and ADCC of broadly neutralizing antibodies against reservoir HIV Y Ren, M Korom, AR Ward, R Truong, D Chan, SH Huang, CM Kovacs, ... Journal of Virology 95 (2), e01808-20, 2020 | 7 | 2020 |
CTL Clonotypes with Higher TCR Affinity Have Better Ability to Reduce the HIV Latent Reservoir NS Lima, H Takata, SH Huang, A Haregot, J Mitchell, S Blackmore, ... The Journal of Immunology 205 (3), 699-707, 2020 | 6 | 2020 |