| Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein DP Williams, K Parker, P Bacha, W Bishai, M Borowski, F Genbauffe, ... Protein Engineering, Design and Selection 1 (6), 493-498, 1987 | 337 | 1987 |
| Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae. J Boyd, MN Oza, JR Murphy Proceedings of the National Academy of Sciences 87 (15), 5968-5972, 1990 | 327 | 1990 |
| Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein. P Bacha, DP Williams, C Waters, JM Williams, JR Murphy, TB Strom The Journal of experimental medicine 167 (2), 612-622, 1988 | 275 | 1988 |
| Structure/function analysis of interleukin-2-toxin (DAB486-IL-2). Fragment B sequences required for the delivery of fragment A to the cytosol of target cells. DP Williams, CE Snider, TB Strom, JR Murphy Journal of Biological Chemistry 265 (20), 11885-11889, 1990 | 256 | 1990 |
| Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein. JR Murphy, W Bishai, M Borowski, A Miyanohara, J Boyd, S Nagle Proceedings of the National Academy of Sciences 83 (21), 8258-8262, 1986 | 229 | 1986 |
| Developmental and adult phenotyping directly from mutant embryonic stem cells SHL George, M Gertsenstein, K Vintersten, E Korets-Smith, J Murphy, ... Proceedings of the National Academy of Sciences 104 (11), 4455-4460, 2007 | 222 | 2007 |
| Structure of the metal-ion-activated diphtheria toxin repressor/ tox operator complex A White, X Ding, JC Vanderspek, JR Murphy, D Ringe Nature 394 (6692), 502-506, 1998 | 219 | 1998 |
| Iron, DtxR, and the regulation of diphtheria toxin expression X Tao, N Schiering, H Zeng, D Ringe, JR Murphy Molecular microbiology 14 (2), 191-197, 1994 | 196 | 1994 |
| Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process JR Murphy Toxins 3 (3), 294-308, 2011 | 194 | 2011 |
| Abnormal distribution of the helper-inducer and suppressor-inducer T-lymphocyte subsets in the rheumatoid joint C Pitzalis, G Kingsley, J Murphy, G Panayi Clinical immunology and immunopathology 45 (2), 252-258, 1987 | 188 | 1987 |
| Nucleotide Sequence and Expression of the Diphtheria tox228 Gene in Escherichia coli M Kaczorek, F Delpeyroux, N Chenciner, RE Streeck, JR Murphy, ... Science 221 (4613), 855-858, 1983 | 159 | 1983 |
| Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery E Lemichez, M Bomsel, G Devilliers, J van der Spek, JR Murphy, ... Molecular microbiology 23 (3), 445-457, 1997 | 154 | 1997 |
| Studies on the molecular epidemiology of diphtheria AM Pappenheimer Jr, JR Murphy The Lancet 322 (8356), 923-926, 1983 | 149 | 1983 |
| Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor YC Manabe, BJ Saviola, L Sun, JR Murphy, WR Bishai Proceedings of the National Academy of Sciences 96 (22), 12844-12848, 1999 | 135 | 1999 |
| Interleukin 2 receptor‐targeted cytotoxicity. Receptor binding requirements for entry of a diphtheria toxin‐related interleukin 2 fusion protein into cells CA Waters, PA Schimke, CE Snider, K Itoh, KA Smith, JC Nichols, ... European journal of immunology 20 (4), 785-791, 1990 | 134 | 1990 |
| Hybrid molecules having translocation region and cell-binding region JR Murphy US Patent 5,668,255, 1997 | 133 | 1997 |
| Structures of the apo-and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae. N Schiering, X Tao, H Zeng, JR Murphy, GA Petsko, D Ringe Proceedings of the National Academy of Sciences 92 (21), 9843-9850, 1995 | 126 | 1995 |
| Commercial DNA extraction kits impact observed microbial community composition in permafrost samples TA Vishnivetskaya, AC Layton, MCY Lau, A Chauhan, KR Cheng, ... FEMS microbiology ecology 87 (1), 217-230, 2014 | 120 | 2014 |
| Binding of the metalloregulatory protein DtxR to the diphtheria tox operator requires a divalent heavy metal ion and protects the palindromic sequence from DNase I digestion. X Tao, JR Murphy Journal of Biological Chemistry 267 (30), 21761-21764, 1992 | 118 | 1992 |
| Identification of the primary metal ion-activation sites of the diphtheria tox represser by X-ray crystallography and site-directed mutational analysis X Ding, H Zeng, N Schiering, D Ringe, JR Murphy Nature structural biology 3 (4), 382-387, 1996 | 113 | 1996 |
