Renee Otten
Renee Otten
Postdoctoral fellow, Brandeis University
Verified email at
Cited by
Cited by
Long unfolded linkers facilitate membrane protein import through the nuclear pore complex
AC Meinema, JK Laba, RA Hapsari, R Otten, FAA Mulder, A Kralt, ...
Science 333 (6038), 90-93, 2011
Using ancient protein kinases to unravel a modern cancer drug’s mechanism
C Wilson, RV Agafonov, M Hoemberger, S Kutter, A Zorba, J Halpin, ...
Science 347 (6224), 882-886, 2015
Subpolar addition of new cell wall is directed by DivIVA in mycobacteria
X Meniche, R Otten, MS Siegrist, CE Baer, KC Murphy, CR Bertozzi, ...
Proceedings of the National Academy of Sciences 111 (31), E3243-E3251, 2014
Fluoride resistance and transport by riboswitch-controlled CLC antiporters
RB Stockbridge, HH Lim, R Otten, C Williams, T Shane, Z Weinberg, ...
Proceedings of the National Academy of Sciences 109 (38), 15289-15294, 2012
The energy landscape of adenylate kinase during catalysis
SJ Kerns, RV Agafonov, YJ Cho, F Pontiggia, R Otten, DV Pachov, ...
Nature Structural and Molecular Biology 22 (2), 124, 2015
Energetic dissection of Gleevec's selectivity toward human tyrosine kinases
RV Agafonov, C Wilson, R Otten, V Buosi, D Kern
Nature Structural and Molecular Biology 21 (10), 848, 2014
Comprehensive and cost-effective NMR spectroscopy of methyl groups in large proteins
R Otten, B Chu, KD Krewulak, HJ Vogel, FAA Mulder
Journal of the American Chemical Society 132 (9), 2952-2960, 2010
Probing Microsecond Time Scale Dynamics in Proteins by Methyl 1H Carr−Purcell−Meiboom−Gill Relaxation Dispersion NMR Measurements. Application to Activation of the Signaling …
R Otten, J Villali, D Kern, FAA Mulder
Journal of the American Chemical Society 132 (47), 17004-17014, 2010
Cavity as a source of conformational fluctuation and high-energy state: High-pressure NMR study of a cavity-enlarged mutant of T4Lysozyme
A Maeno, D Sindhikara, F Hirata, R Otten, FW Dahlquist, S Yokoyama, ...
Biophysical journal 108 (1), 133-145, 2015
Protein surface and core dynamics show concerted hydration‐dependent activation
K Wood, FX Gallat, R Otten, AJ Van Heel, M Lethier, L Van Eijck, M Moulin, ...
Angewandte Chemie International Edition 52 (2), 665-668, 2013
Conformational selection in a protein-protein interaction revealed by dynamic pathway analysis
KS Chakrabarti, RV Agafonov, F Pontiggia, R Otten, MK Higgins, ...
Cell reports 14 (1), 32-42, 2016
Conformational fluctuations affect protein alignment in dilute liquid crystal media
M Louhivuori, R Otten, K Lindorff-Larsen, A Annila
Journal of the American Chemical Society 128 (13), 4371-4376, 2006
Rescue of conformational dynamics in enzyme catalysis by directed evolution
R Otten, L Liu, LR Kenner, MW Clarkson, D Mavor, DS Tawfik, D Kern, ...
Nature Communications 9 (1), 1314, 2018
The solution structure, binding properties, and dynamics of the bacterial siderophore-binding protein FepB
BCH Chu, R Otten, KD Krewulak, FAA Mulder, HJ Vogel
Journal of Biological Chemistry 289 (42), 29219-29234, 2014
Cystathionine β-synthase (CBS) domains 1 and 2 fulfill different roles in ionic strength sensing of the ATP-binding cassette (ABC) transporter OpuA
A Karasawa, GB Erkens, RPA Berntsson, R Otten, GK Schuurman-Wolters, ...
Journal of Biological Chemistry 286 (43), 37280-37291, 2011
Optimized co-solute paramagnetic relaxation enhancement for the rapid NMR analysis of a highly fibrillogenic peptide
NA Oktaviani, MW Risør, YH Lee, RP Megens, DH de Jong, R Otten, ...
Journal of biomolecular NMR 62 (2), 129-142, 2015
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
RAP Pádua, Y Sun, I Marko, W Pitsawong, JB Stiller, R Otten, D Kern
Nature communications 9 (1), 4507, 2018
Comprehensive analysis of NMR data using advanced line shape fitting
M Niklasson, R Otten, A Ahlner, C Andresen, J Schlagnitweit, K Petzold, ...
Journal of biomolecular NMR 69 (2), 93-99, 2017
A minor conformation of a lanthanide tag on adenylate kinase characterized by paramagnetic relaxation dispersion NMR spectroscopy
MAS Hass, WM Liu, RV Agafonov, R Otten, LA Phung, JT Schilder, D Kern, ...
Journal of biomolecular NMR 61 (2), 123-136, 2015
Comprehensive determination of 3JHNHα for unfolded proteins using 13C′-resolved spin-echo difference spectroscopy
R Otten, K Wood, FAA Mulder
Journal of biomolecular NMR 45 (4), 343, 2009
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