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Jae Kyu Ryu
Jae Kyu Ryu
Scientific Program Leader, Gladstone Institutes; Assistant Adjunct Professor of Neurology, UCSF
Verified email at gladstone.ucsf.edu
Title
Cited by
Cited by
Year
Resolving postoperative neuroinflammation and cognitive decline
N Terrando, LI Eriksson, J Kyu Ryu, T Yang, C Monaco, M Feldmann, ...
Annals of neurology 70 (6), 986-995, 2011
6372011
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
D Davalos, J Kyu Ryu, M Merlini, KM Baeten, N Le Moan, MA Petersen, ...
Nature communications 3 (1), 1227, 2012
5702012
A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain
JK Ryu, JG McLarnon
Journal of cellular and molecular medicine 13 (9a), 2911-2925, 2009
4412009
Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-β after vascular damage
C Schachtrup, JK Ryu, MJ Helmrick, E Vagena, DK Galanakis, JL Degen, ...
Journal of Neuroscience 30 (17), 5843-5854, 2010
4152010
Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics
MA Petersen, JK Ryu, K Akassoglou
Nature Reviews Neuroscience 19 (5), 283-301, 2018
3562018
Fibrinogen induces microglia-mediated spine elimination and cognitive impairment in an Alzheimer’s disease model
M Merlini, VA Rafalski, PER Coronado, TM Gill, M Ellisman, ...
Neuron 101 (6), 1099-1108. e6, 2019
2972019
Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism
T Xu, KM Stewart, X Wang, K Liu, M Xie, JK Ryu, K Li, T Ma, H Wang, L Ni, ...
Nature 548 (7666), 228-233, 2017
2922017
Upregulated Expression of Purinergic P2X7 Receptor in Alzheimer Disease and Amyloid-β Peptide-Treated Microglia and in Peptide-Injected Rat Hippocampus
JG McLarnon, JK Ryu, DG Walker, HB Choi
Journal of Neuropathology & Experimental Neurology 65 (11), 1090-1097, 2006
2912006
Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase
HB Choi, GRJ Gordon, N Zhou, C Tai, RL Rungta, J Martinez, TA Milner, ...
Neuron 75 (6), 1094-1104, 2012
2712012
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation
JK Ryu, MA Petersen, SG Murray, KM Baeten, A Meyer-Franke, JP Chan, ...
Nature communications 6 (1), 8164, 2015
2632015
Fractalkine and fractalkine receptors in human neurons and glial cells
K Hatori, A Nagai, R Heisel, JK Ryu, SU Kim
Journal of neuroscience research 69 (3), 418-426, 2002
2592002
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease
JK Ryu, J Kim, SJ Cho, K Hatori, A Nagai, HB Choi, MC Lee, ...
Neurobiology of disease 16 (1), 68-77, 2004
2232004
Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain
HB Choi, JK Ryu, SU Kim, JG McLarnon
Journal of Neuroscience 27 (18), 4957-4968, 2007
2102007
Fibrinogen activates BMP signaling in oligodendrocyte progenitor cells and inhibits remyelination after vascular damage
MA Petersen, JK Ryu, KJ Chang, A Etxeberria, S Bardehle, AS Mendiola, ...
Neuron 96 (5), 1003-1012. e7, 2017
1702017
Minocycline inhibits neuronal death and glial activation induced by β‐amyloid peptide in rat hippocampus
JK Ryu, S Franciosi, P Sattayaprasert, SU Kim, JG McLarnon
Glia 48 (1), 85-90, 2004
1662004
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration
JK Ryu, VA Rafalski, A Meyer-Franke, RA Adams, SB Poda, ...
Nature immunology 19 (11), 1212-1223, 2018
1652018
SIRT1 deacetylates RORγt and enhances Th17 cell generation
HW Lim, SG Kang, JK Ryu, B Schilling, M Fei, IS Lee, A Kehasse, ...
Journal of Experimental Medicine 212 (5), 607-617, 2015
1652015
Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease
JK Ryu, JG McLarnon
Neuroreport 19 (17), 1715-1719, 2008
1462008
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation
AS Mendiola, JK Ryu, S Bardehle, A Meyer-Franke, KKH Ang, C Wilson, ...
Nature immunology 21 (5), 513-524, 2020
1442020
Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum
JK Ryu, HB Choi, JG McLarnon
Neurobiology of disease 20 (2), 550-561, 2005
1312005
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Articles 1–20