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Joshua D. Rabinowitz
Joshua D. Rabinowitz
Geverifieerd e-mailadres voor princeton.edu
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ...
Nature 462 (7274), 739-744, 2009
45712009
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate
PS Ward, J Patel, DR Wise, O Abdel-Wahab, BD Bennett, HA Coller, ...
Cancer cell 17 (3), 225-234, 2010
22702010
Autophagy and metabolism
JD Rabinowitz, E White
Science 330 (6009), 1344-1348, 2010
22082010
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
BD Bennett, EH Kimball, M Gao, R Osterhout, SJ Van Dien, ...
Nature chemical biology 5 (8), 593-599, 2009
19852009
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
C Commisso, SM Davidson, RG Soydaner-Azeloglu, SJ Parker, ...
Nature 497 (7451), 633-637, 2013
15862013
One-carbon metabolism in health and disease
GS Ducker, JD Rabinowitz
Cell metabolism 25 (1), 27-42, 2017
15752017
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
JY Guo, HY Chen, R Mathew, J Fan, AM Strohecker, G Karsli-Uzunbas, ...
Genes & development 25 (5), 460-470, 2011
14362011
Glucose feeds the TCA cycle via circulating lactate
S Hui, JM Ghergurovich, RJ Morscher, C Jang, X Teng, W Lu, LA Esparza, ...
Nature 551 (7678), 115-118, 2017
13022017
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
A Stincone, A Prigione, T Cramer, MMC Wamelink, K Campbell, ...
Biological Reviews 90 (3), 927-963, 2015
12242015
Quantitative flux analysis reveals folate-dependent NADPH production
J Fan, J Ye, JJ Kamphorst, T Shlomi, CB Thompson, JD Rabinowitz
Nature 510 (7504), 298-302, 2014
10402014
Mitochondria and cancer
WX Zong, JD Rabinowitz, E White
Molecular cell 61 (5), 667-676, 2016
10202016
Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein
JJ Kamphorst, M Nofal, C Commisso, SR Hackett, W Lu, E Grabocka, ...
Cancer research 75 (3), 544-553, 2015
7832015
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
MG Vander Heiden, JW Locasale, KD Swanson, H Sharfi, GJ Heffron, ...
Science 329 (5998), 1492-1499, 2010
7332010
Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry
SU Bajad, W Lu, EH Kimball, J Yuan, C Peterson, JD Rabinowitz
Journal of chromatography A 1125 (1), 76-88, 2006
7132006
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
J Munger, BD Bennett, A Parikh, XJ Feng, J McArdle, HA Rabitz, T Shenk, ...
Nature biotechnology 26 (10), 1179-1186, 2008
7072008
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
JJ Kamphorst, JR Cross, J Fan, E De Stanchina, R Mathew, EP White, ...
Proceedings of the National Academy of Sciences 110 (22), 8882-8887, 2013
6842013
Metabolomics and isotope tracing
C Jang, L Chen, JD Rabinowitz
Cell 173 (4), 822-837, 2018
6652018
Metabolomic analysis and visualization engine for LC− MS data
E Melamud, L Vastag, JD Rabinowitz
Analytical chemistry 82 (23), 9818-9826, 2010
6382010
Analytical strategies for LC–MS-based targeted metabolomics
W Lu, BD Bennett, JD Rabinowitz
Journal of chromatography B 871 (2), 236-242, 2008
6072008
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
6042015
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Artikelen 1–20